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DFTX Overview

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$
0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
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ET
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Intellectia

Loading chart...

High
18.990
Open
18.950
VWAP
18.68
Vol
791.96K
Mkt Cap
1.90B
Low
18.360
Amount
14.80M
EV/EBITDA(TTM)
--
Total Shares
99.70M
EV
1.53B
EV/OCF(TTM)
--
P/S(TTM)
--
Definium Therapeutics, Inc., formerly Mind Medicine (MindMed) Inc., is engaged in developing therapeutics intended to solve the underlying causes of psychiatric and neurological disorders and offer patients long-term remission rather than transient symptom reduction. The Company plans to advance DT1201 ODT toward FDA submissions in the two largest psychiatric markets, generalized anxiety disorder (GAD) and major depressive disorder (MDD). Its late-stage pipeline includes four Phase 3 trials, two each for GAD and MDD, anchored by its lead candidate, DT120 ODT, which has received an FDA Breakthrough Therapy Designation for GAD. In parallel, the Company is engaged in advancing its commercial strategy and operational readiness to support a care model and prepare for the launch of DT120 ODT, if approved and marketed. It also continues to advance its early-stage pipeline, having dosed the first patient in a Phase 2a study of DT4023 in adults with autism spectrum disorder (ASD).
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Events Timeline

(ET)
2026-02-26
16:20:00
Definium Therapeutics Cash Reserves Increase to $411.6 Million
select
2026-02-26
10:20:00
AtaiBeckley Reports Phase 2 Results for EMP-01 in Social Anxiety Disorder
select

News

Newsfilter
8.5
03-09Newsfilter
Helus Pharma Advances New Drug for Anxiety Treatment
  • Clinical Trial Progress: Helus Pharma's Phase 2 signal detection study for HLP004 showed that among 36 patients, those receiving 20 mg achieved a mean HAM-A score reduction of 10.4 points (p<0.0001) at six weeks, indicating significant efficacy and potential for new treatment options for anxiety patients.
  • Strong Market Demand: The global economy loses over $1 trillion annually due to depression and anxiety, with approximately 30% of patients suffering from treatment-resistant depression, driving the need for novel rapid-acting therapies, which Helus Pharma aims to address.
  • Sufficient Financial Support: As of December 31, 2025, Helus Pharma reported $195.1 million in cash, providing ample resources to support the ongoing advancement of its multi-asset clinical pipeline, ensuring the company maintains a competitive edge in a challenging market.
  • Strengthened Leadership: Helus Pharma recently appointed former Pfizer Chief Medical Officer Freda Lewis-Hall to its Board of Directors and as Chair of the Scientific Advisory Committee, leveraging her extensive industry experience to further enhance the company's scientific development and market strategy.
PRnewswire
8.5
03-09PRnewswire
Helus Pharma Advances Mental Health Treatments with Promising Phase 2 Results
  • Clinical Trial Progress: Helus Pharma's Phase 2 signal detection study for HLP004 showed that patients receiving the 20 mg dose achieved a mean HAM-A score reduction of 10.4 points (p<0.0001) at six weeks, indicating significant efficacy and potential as an adjunctive treatment for generalized anxiety disorder.
  • Strong Market Demand: The global economy loses over $1 trillion annually due to depression and anxiety, with approximately 30% of major depressive disorder patients being treatment-resistant, driving urgent demand for novel therapeutic mechanisms that Helus Pharma aims to address.
  • Sufficient Financial Support: As of December 31, 2025, Helus Pharma reported $195.1 million in cash, ensuring continued advancement across its multi-asset clinical pipeline and safeguarding its research activities in the mental health sector from financial constraints.
  • Enhanced Leadership: The appointment of Dr. Freda Lewis-Hall to Helus Pharma's Board and as Chair of the Scientific Advisory Committee, leveraging her extensive experience at Pfizer, is expected to provide crucial guidance for the company's scientific development and market strategy.
NASDAQ.COM
2.0
02-27NASDAQ.COM
Definium (DFTX) Q4 2025 Earnings Call Transcript
Newsfilter
8.5
02-27Newsfilter
Helus Pharma Advances Mental Health Drug Development
  • Clinical Trial Progress: Helus Pharma's SPL026 showed significant efficacy in a randomized Phase 2 trial for major depressive disorder, with a mean MADRS score reduction of 7.35 in the 21.5 mg dose group among 34 participants, indicating its potential in the mental health sector.
  • New Drug Development: The company is advancing HLP003 through Phase 3 trials, which has received FDA Breakthrough Therapy Designation, with preliminary data showing a 100% response rate and 71% remission rate at 12 months, highlighting its importance in treating major depressive disorder.
  • Financial Support: As of December 31, 2025, Helus Pharma reported $195.1 million in cash reserves, providing strong financial backing for the continued advancement of its multi-asset clinical pipeline, ensuring sustainability for future R&D efforts.
  • Market Outlook: As regulatory approvals for mental health drugs draw closer, Helus Pharma and its peers are reshaping the market perception of psychedelic drugs, which is expected to create significant commercial opportunities and enhance market share for the company.
PRnewswire
8.5
02-27PRnewswire
Helus Pharma Advances Psychedelic Drug Clinical Trials
  • Clinical Trial Progress: Helus Pharma's SPL026 achieved a mean MADRS difference of -7.35 (p=0.023) in a randomized Phase 2 trial involving 34 participants with major depressive disorder, indicating significant efficacy and potential in the mental health sector.
  • Drug Development Strategy: Helus Pharma's HLP003 has received FDA Breakthrough Therapy Designation and is advancing through two pivotal Phase 3 studies, with topline data expected in Q4 2026, showcasing the company's ongoing innovation and competitiveness in depression treatment.
  • Financial Support: As of December 31, 2025, Helus Pharma reported $195.1 million in cash, ensuring continued advancement across its multi-asset clinical pipeline, demonstrating a strong financial foundation for R&D efforts.
  • Industry Recognition: A consensus statement from the U.S. National Network of Depression Centers indicates that academia is preparing to integrate psychedelics into routine clinical practice, reflecting the growing acceptance of Helus Pharma and its peers in the mental health treatment landscape.
seekingalpha
9.5
02-27seekingalpha
Definium Therapeutics Q4 2025 Earnings Call Insights
  • R&D Expense Increase: Research and development expenses reached $117.7 million for 2025, up from $65.3 million in 2024, representing a significant investment in clinical development despite a net loss of $183.8 million, indicating financial pressure from high expenditures.
  • Improved Cash Position: As of December 31, 2025, the company reported cash, cash equivalents, and investments totaling $411.6 million, a substantial increase from $273.7 million in 2024, which is expected to fund operations into 2028, enhancing flexibility for future R&D and market access initiatives.
  • Clinical Trial Progress: Management anticipates three Phase III readouts in 2026, with the first expected in late Q2, which will not only facilitate the company's transition to commercialization but also potentially offer new hope for treating psychiatric disorders.
  • Leadership Expansion: The appointment of Matthew Wiley as Chief Commercial Officer marks a significant step in the company's commercialization strategy, aiming to deliver a high-touch service experience that strengthens partnerships with clinical trial sites and enhances market access and brand recognition.
Wall Street analysts forecast DFTX stock price to rise
9 Analyst Rating
Wall Street analysts forecast DFTX stock price to rise
9 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
20.00
Averages
35.89
High
61.00
Current: 0.000
sliders
Low
20.00
Averages
35.89
High
61.00
Maxim
Michael Okunewitch
Buy
maintain
$18 -> $40
AI Analysis
2026-03-04
Reason
Maxim
Michael Okunewitch
Price Target
$18 -> $40
AI Analysis
2026-03-04
maintain
Buy
Reason
Maxim analyst Michael Okunewitch raised the firm's price target on Definium Therapeutics to $40 from $18 and keeps a Buy rating on the shares after its Q4 results. The company's cash on the balance sheet should provide sufficient funding into 2028, through a busy 2026 with three Phase 3 pivotal readouts for DT120, the analyst tells investors in a research note. As the readout in MDD - major depressive disorder - approaches, the firm is factoring in revenues for MDD in 2029, Maxim added.
Wolfe Research
Outperform
initiated
$25
2026-02-23
Reason
Wolfe Research
Price Target
$25
2026-02-23
initiated
Outperform
Reason
Wolfe Research initiated coverage of Definium Therapeutics with an Outperform rating and $25 price target. The firm launched coverage of the neuroscience biotech sector with a "portfolio of high conviction names across multiple therapeutic areas." Wolfe names Definium its top pick for psychedelics, which is one of its favorite central nervous system areas. It sees the stock moving up in 2026.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for DFTX
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Valuation Metrics

The current forward P/E ratio for Definium Therapeutics Inc (DFTX.O) is --, compared to its 5-year average forward P/E of --. For a more detailed relative valuation and DCF analysis to assess Definium Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PE
Current PE
NaN
Overvalued PE
Undervalued PE

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average EV/EBITDA
Current EV/EBITDA
NaN
Overvalued EV/EBITDA
Undervalued EV/EBITDA

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
Current PS
NaN
Overvalued PS
Undervalued PS

Financials

AI Analysis
Annual
Quarterly

Whales Holding DFTX

D
Driehaus Capital Management LLC
Holding
DFTX
+8.18%
3M Return
C
Commodore Capital LP
Holding
DFTX
+6.85%
3M Return
A
Avoro Capital Advisors LLC
Holding
DFTX
-2.32%
3M Return
D
Deep Track Capital, LP
Holding
DFTX
-5.04%
3M Return

Trading Trends

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Frequently Asked Questions

What is Definium Therapeutics Inc (DFTX) stock price today?

The current price of DFTX is 18.7 USD — it has decreased -1.84

What is Definium Therapeutics Inc (DFTX)'s business?

Definium Therapeutics, Inc., formerly Mind Medicine (MindMed) Inc., is engaged in developing therapeutics intended to solve the underlying causes of psychiatric and neurological disorders and offer patients long-term remission rather than transient symptom reduction. The Company plans to advance DT1201 ODT toward FDA submissions in the two largest psychiatric markets, generalized anxiety disorder (GAD) and major depressive disorder (MDD). Its late-stage pipeline includes four Phase 3 trials, two each for GAD and MDD, anchored by its lead candidate, DT120 ODT, which has received an FDA Breakthrough Therapy Designation for GAD. In parallel, the Company is engaged in advancing its commercial strategy and operational readiness to support a care model and prepare for the launch of DT120 ODT, if approved and marketed. It also continues to advance its early-stage pipeline, having dosed the first patient in a Phase 2a study of DT4023 in adults with autism spectrum disorder (ASD).

What is the price predicton of DFTX Stock?

Wall Street analysts forecast DFTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for DFTX is35.89 USD with a low forecast of 20.00 USD and a high forecast of 61.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Definium Therapeutics Inc (DFTX)'s revenue for the last quarter?

Definium Therapeutics Inc revenue for the last quarter amounts to -47.58M USD, increased 46.57

What is Definium Therapeutics Inc (DFTX)'s earnings per share (EPS) for the last quarter?

Definium Therapeutics Inc. EPS for the last quarter amounts to -42975000.00 USD, decreased

How many employees does Definium Therapeutics Inc (DFTX). have?

Definium Therapeutics Inc (DFTX) has 105 emplpoyees as of March 11 2026.

What is Definium Therapeutics Inc (DFTX) market cap?

Today DFTX has the market capitalization of 1.90B USD.