CYCC Overview

Acquisition Announcement: Bio Green Med Solution, Inc. has completed the acquisition of Fitters Sdn. Bhd., a Malaysian company specializing in fire safety equipment, making it a wholly-owned subsidiary. This transaction was approved by stockholders on September 4, 2025.

Business Diversification: The acquisition allows Bio Green Med to diversify its portfolio by adding fire protection products and services to its existing pharmaceutical operations, with a focus on creating long-term value for shareholders.

Palantir Technologies Financial Results: Palantir's shares rose 5.3% after reporting second-quarter revenue of $1.004 billion, exceeding analyst expectations, and raising its full-year guidance.

Stock Movements in Pre-Market Trading: Several stocks saw significant pre-market trading movements, including Arteris, Inc. (+56.4%) and STAAR Surgical Company (+45.2%), while Inspire Medical Systems (-25%) and Ichor Holdings, Ltd. (-24.3%) experienced notable declines.

Stock Surge: Cyclacel Pharmaceuticals Inc. (CYCC) saw a 34.56% increase in its stock price during after-hours trading, reaching $13.20, following the announcement of promising preclinical data for biliary tract cancer treatment.

Research Findings: The study indicated that biliary tract cancer cells are sensitive to plogosertib, a PLK1 inhibitor, and suggested BUBR1 as a potential biomarker for assessing treatment effectiveness, highlighting a new strategy for BTC therapy.

Biliary Tract Cancer Research: Cyclacel Pharmaceuticals announced a preclinical study showing that plogosertib, a PLK1 inhibitor, effectively induces apoptosis in biliary tract cancer (BTC) cells, particularly those with high BUBR1 expression, suggesting its potential as a treatment strategy.

Clinical Development of Plogosertib: The company is advancing plogosertib through clinical trials, demonstrating good tolerance and preliminary efficacy in various cancers, highlighting the urgent need for effective therapies for aggressive BTC.

Block, Inc. Stock Surge: Shares of Block, Inc. rose 9.6% to $79.81 in pre-market trading as the company prepares to debut in the S&P 500, replacing Hess Corp. on July 23.

Pre-Market Trading Highlights: Other notable stock movements included GlucoTrack, Inc. surging 82%, Dynamix Corporation rising 55.4%, while Expion360 Inc. and Telomir Pharmaceuticals saw declines of 15.2% and 13.6%, respectively.

U.S. Stock Market Performance: U.S. stocks showed mixed results with the Dow rising slightly by 0.08% while the Nasdaq fell by 0.1%. Bank of America reported better-than-expected earnings, and healthcare shares increased by 1.2%, whereas energy stocks declined by 0.8%.

Global Market Overview: European shares were mixed, with the STOXX 600 down 0.2% and Spain's IBEX 35 up 0.3%. Asian markets also closed mixed, with Japan's Nikkei and Hong Kong's Hang Seng both falling slightly, while India's BSE Sensex gained 0.08%.