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CNTA.O Overview

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$
0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

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High
39.620
Open
39.600
VWAP
39.59
Vol
533.37K
Mkt Cap
6.13B
Low
39.560
Amount
21.12M
EV/EBITDA(TTM)
--
Total Shares
154.73M
EV
5.96B
EV/OCF(TTM)
--
P/S(TTM)
--
Centessa Pharmaceuticals plc is a clinical-stage pharmaceutical company. The Company is developing a new class of potential therapies within its orexin receptor 2 (OX2R) agonist program for the treatment of excessive daytime sleepiness (EDS), impaired attention, cognitive deficits, fatigue and other symptoms across neurological, neurodegenerative and neuropsychiatric disorders. It also has an early-stage immuno-oncology program focused on its LockBody technology platform. Its OX2R agonist pipeline includes ORX750, its advanced OX2R agonist development candidate, and ORX142, ORX489 and OX2R agonists in preclinical development. Its ORX750, an investigational, orally administered, highly potent and selective OX2R agonist, is in a Phase IIa study of participants with narcolepsy type 1 (NT1), NT2 and idiopathic hypersomnia (IH). ORX142 is the second OX2R agonist development candidate being advanced for the treatment of neurological and neurodegenerative disorders and other symptoms.
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Events Timeline

(ET)
2026-04-01
07:40:00
LifeSci Capital Downgrades Centessa to Market Perform After Eli Lilly Acquisition
select
2026-03-31 (ET)
2026-03-31
16:30:00
Dow Jones Index Rises 2.49% to 46,341.51
select
2026-03-31
13:20:00
Alkermes Shares Rise 15% Following M&A Activity
select

News

PRnewswire
7.0
05-12PRnewswire
Investor Rights Law Firm Investigates Multiple Companies
  • Legal Investigation: Halper Sadeh LLC is investigating Centessa Pharmaceuticals plc, Whitestone REIT, and Green Dot Corporation for potential violations of federal securities laws and breaches of fiduciary duties, which may expose shareholders to financial losses.
  • Centessa Transaction Details: Centessa Pharmaceuticals is being sold to Eli Lilly for $38.00 per share in cash, plus a non-transferrable right worth up to $9.00, which could impact shareholder interests and future earnings.
  • Whitestone REIT Sale: Whitestone REIT is being sold to Ares Management Corporation for $19.00 per share, and Halper Sadeh LLC may seek to increase the transaction price to ensure fair compensation for shareholders.
  • Green Dot Transaction Structure: Green Dot Corporation's sale price includes $8.11 in cash and 0.2215 shares of a new publicly traded bank holding company for each share, with Halper Sadeh LLC representing shareholders to negotiate better terms and transparency.
Fool
8.5
04-28Fool
Eli Lilly's Dominance in Weight Loss Market
  • Weight Loss Market Growth: Eli Lilly's anti-obesity drug Zepbound is experiencing rapid sales growth, which is expected to solidify the company's leadership in the fast-expanding weight loss market, especially with the recent launch of Foundayo that further broadens its addressable market.
  • Diverse Product Portfolio: Beyond Zepbound, Eli Lilly boasts other drugs like Verzenio and Taltz, which generated $5.7 billion and $3.6 billion in sales last year, respectively, showcasing the company's strong growth potential in oncology and immunology, effectively mitigating competitive pressures.
  • Strategic Acquisition Plans: Eli Lilly recently acquired Kelonia Therapeutics for $3.25 billion, enhancing its gene therapy platform expected to improve cancer treatment, while also expanding its neuroscience pipeline through the acquisition of Centessa Pharmaceuticals and deepening its oncology pipeline with Scorpion Therapeutics.
  • Competitive Market Advantage: Compared to rival Novo Nordisk, Eli Lilly has a clear advantage in product diversity, allowing it to maintain its lead in the weight loss market, and despite facing competition from new drugs, it continues to drive long-term revenue growth.
NASDAQ.COM
8.5
04-28NASDAQ.COM
Eli Lilly's Leadership in the Weight Loss Market
  • Weight Loss Market Growth: Eli Lilly's anti-obesity drug Zepbound is experiencing rapid sales growth, underscoring the company's leadership in the weight loss market, which is expected to drive overall revenue growth and enhance competitive positioning.
  • Diverse Product Line: Eli Lilly achieved $5.7 billion in sales for its cancer treatment Verzenio, an 8% year-over-year increase, while immunosuppressant Taltz reached $3.6 billion, demonstrating its strong capabilities across multiple therapeutic areas that help mitigate market competition.
  • Strategic Acquisition: Eli Lilly's acquisition of Kelonia Therapeutics for $3.25 billion grants access to an innovative gene therapy platform, expected to improve cancer treatment outcomes and further strengthen its competitive edge in genetic medicine.
  • Future Growth Potential: Analysts expect Eli Lilly's new drugs Ebglyss, Jaypirca, and Kisunla to generate over $1 billion in annual sales, showcasing the company's ongoing innovation and growth potential across various fields.
stocktwits
8.5
04-27stocktwits
Eli Lilly Acquires Ajax Therapeutics for $2.3 Billion
  • Acquisition Activity: Eli Lilly accelerates its acquisition strategy in 2026 with the buyout of Ajax Therapeutics valued at up to $2.3 billion, including milestone payments, further solidifying its position in blood cancer treatments.
  • Drug Development: Ajax's lead drug, AJ1-11095, is a next-generation JAK2 inhibitor currently in Phase 1 trials for patients with Myelofibrosis, aiming to expand treatment options for patients with rare blood cancers.
  • Strategic Positioning: This marks Lilly's sixth acquisition this year, including a $6.3 billion deal for Centessa Pharmaceuticals focused on sleep disorders, demonstrating its commitment to deepening its oncology pipeline.
  • Market Sentiment: Despite nearly a 20% decline in LLY shares in 2026, retail sentiment on Stocktwits remains bullish, indicating confidence in the company's acquisition strategy and its potential to enhance future growth.
PRnewswire
7.0
04-20PRnewswire
Investor Rights Law Firm Investigates Multiple Companies
  • Investigation Focus: Halper Sadeh LLC is investigating Centessa Pharmaceuticals plc, KORE Group Holdings, Inc., and Clearwater Analytics Holdings, Inc. for potential violations of federal securities laws and breaches of fiduciary duties to shareholders.
  • Transaction Details: Centessa Pharmaceuticals is being sold to Eli Lilly for $38.00 per share in cash plus a non-transferrable right worth up to $9.00, KORE Group is selling to Searchlight Capital Partners and Abry Partners for $9.25 per share, while Clearwater Analytics is being sold to Permira and Warburg Pincus for $24.55 per share.
  • Shareholder Rights: Halper Sadeh LLC encourages shareholders to contact them to discuss their rights and options at no cost, aiming to secure increased consideration and additional disclosures for shareholders involved in these transactions.
  • Legal Support: The firm represents investors globally, focusing on securities fraud and corporate misconduct, having successfully recovered millions for defrauded investors, which underscores their expertise in protecting investor rights.
CNBC
8.5
04-20CNBC
Honeywell Sells Business to Reshape Portfolio Amid Market Uncertainty
  • Honeywell Business Sale: Honeywell sells its Productivity Solutions and Services (PSS) business to Brady Corporation for $1.4 billion in cash, a strategic move to divest cyclical, slower-growing, lower-margin operations, thereby enhancing the overall quality of its portfolio.
  • Market Reaction Stable: Despite a 5% rise in oil prices due to uncertainty over commercial shipping traffic in the Strait of Hormuz, the market's decline was less severe than feared, as Treasury yields remained relatively unchanged, indicating a stable investor sentiment.
  • Eli Lilly Acquisition Moves: Eli Lilly acquires clinical-stage biotech firm Kelonia Therapeutics for $3.25 billion in cash, aiming to bolster its cancer treatment pipeline, with the deal potentially worth up to $7 billion, showcasing the company's aggressive expansion strategy in oncology.
  • Active IPO Market: In spite of uncertainties from the Iran conflict, Jersey Mike's confidentially files for an IPO with a valuation of approximately $8 billion, reflecting ongoing interest in new public offerings and further driving growth in investment banking activities.
Wall Street analysts forecast CNTA.O stock price to rise
13 Analyst Rating
Wall Street analysts forecast CNTA.O stock price to rise
13 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
27.00
Averages
38.75
High
62.00
Current: 0.000
sliders
Low
27.00
Averages
38.75
High
62.00
Wells Fargo
Overweight
to
Equal Weight
downgrade
$42
AI Analysis
2026-04-20
Reason
Wells Fargo
Price Target
$42
AI Analysis
2026-04-20
downgrade
Overweight
to
Equal Weight
Reason
Wells Fargo downgraded Centessa (CNTA) to Equal Weight from Overweight with a $42 price target after after Eli Lilly (LLY) announced an agreement to acquire the company for $38 per share in cash plus a non-transferable contingent value right worth up to $9 per share.
Truist
Danielle Brill
Buy
to
Hold
downgrade
$38
2026-04-12
Reason
Truist
Danielle Brill
Price Target
$38
2026-04-12
downgrade
Buy
to
Hold
Reason
Truist analyst Danielle Brill downgraded Centessa (CNTA) to Hold from Buy with a $38 price target after Eli Lilly (LLY) announced an agreement to acquire the company for $38 per share in cash plus a non-transferable contingent value right worth up to $9 per share.
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Valuation Metrics

The current forward P/E ratio for Centessa Pharmaceuticals PLC (CNTA.O) is 0.00, compared to its 5-year average forward P/E of -6.23. For a more detailed relative valuation and DCF analysis to assess Centessa Pharmaceuticals PLC's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-6.23
Current PE
0.00
Overvalued PE
-2.37
Undervalued PE
-10.08

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-5.02
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-0.10
Undervalued EV/EBITDA
-9.93

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
254.55
Current PS
337.00
Overvalued PS
1285.55
Undervalued PS
-776.44

Financials

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Frequently Asked Questions

What is Centessa Pharmaceuticals PLC (CNTA.O) stock price today?

The current price of CNTA.O is 39.59 USD — it has decreased -0.03

What is Centessa Pharmaceuticals PLC (CNTA.O)'s business?

Centessa Pharmaceuticals plc is a clinical-stage pharmaceutical company. The Company is developing a new class of potential therapies within its orexin receptor 2 (OX2R) agonist program for the treatment of excessive daytime sleepiness (EDS), impaired attention, cognitive deficits, fatigue and other symptoms across neurological, neurodegenerative and neuropsychiatric disorders. It also has an early-stage immuno-oncology program focused on its LockBody technology platform. Its OX2R agonist pipeline includes ORX750, its advanced OX2R agonist development candidate, and ORX142, ORX489 and OX2R agonists in preclinical development. Its ORX750, an investigational, orally administered, highly potent and selective OX2R agonist, is in a Phase IIa study of participants with narcolepsy type 1 (NT1), NT2 and idiopathic hypersomnia (IH). ORX142 is the second OX2R agonist development candidate being advanced for the treatment of neurological and neurodegenerative disorders and other symptoms.

What is the price predicton of CNTA.O Stock?

Wall Street analysts forecast CNTA.O stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CNTA.O is38.75 USD with a low forecast of 27.00 USD and a high forecast of 62.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Centessa Pharmaceuticals PLC (CNTA.O)'s revenue for the last quarter?

Centessa Pharmaceuticals PLC revenue for the last quarter amounts to 0.00 USD, decreased -100.00

What is Centessa Pharmaceuticals PLC (CNTA.O)'s earnings per share (EPS) for the last quarter?

Centessa Pharmaceuticals PLC. EPS for the last quarter amounts to -0.52 USD, increased 160.00

How many employees does Centessa Pharmaceuticals PLC (CNTA.O). have?

Centessa Pharmaceuticals PLC (CNTA.O) has 118 emplpoyees as of May 17 2026.

What is Centessa Pharmaceuticals PLC (CNTA.O) market cap?

Today CNTA.O has the market capitalization of 6.13B USD.