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CGTX Overview

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ET
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ET
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Intellectia

Loading chart...

High
0.765
Open
0.759
VWAP
0.64
Vol
4.86M
Mkt Cap
53.13M
Low
0.550
Amount
3.10M
EV/EBITDA(TTM)
--
Total Shares
89.35M
EV
28.43M
EV/OCF(TTM)
--
P/S(TTM)
--
Cognition Therapeutics, Inc. is a clinical-stage biopharmaceutical company engaged in the discovery and development of small molecule therapeutics targeting age-related degenerative disorders of the central nervous system and retina. The Company is investigating its lead candidate, zervimesine (CT1812), in clinical programs in dementia with Lewy bodies (DLB) and Alzheimer’s disease. Its CT1812 and pipeline of sigma-2 modulators can regulate pathways that are impaired in these diseases for the treatment of degenerative diseases. Its lead product candidate, CT1812, is an orally delivered, small molecule designed to protect neuronal synapses by preventing the binding of oligomers of pathogenic proteins. Its pipeline candidates were discovered using proprietary biology and chemistry platforms designed to identify novel drug targets and disease-modifying therapies that address dysregulated pathways. It is developing other product candidates in the area of synucleinopathies.
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Events Timeline

(ET)
2026-03-17
07:50:00
Cognition Therapeutics Study Shows Zervimesine Slows DLB Progression
select
2026-03-02 (ET)
2026-03-02
07:40:00
Cognition Therapeutics Advances Zervimesine Development
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2026-01-27 (ET)
2026-01-27
07:40:00
Cognition Therapeutics Holds Meeting with FDA to Discuss Zervimesine
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2026-01-06 (ET)
2026-01-06
07:40:00
Cognition Therapeutics Publishes Zervimesine Study Results
select
2025-12-18 (ET)
2025-12-18
16:20:00
Cognition Therapeutics Files $300M Mixed Securities Shelf
select
2025-12-01 (ET)
2025-12-01
07:40:00
Cognition Therapeutics Plans Registrational Program for Zervimesine in Alzheimer's Disease
select
2025-11-13 (ET)
2025-11-13
07:38:20
Cognition Therapeutics finishes enrolling participants for Phase 2 trial of Zervimesine
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News

seekingalpha
9.5
03-26seekingalpha
Cognition Therapeutics Reports Better-Than-Expected FY GAAP EPS
  • Earnings Highlights: Cognition Therapeutics reported a FY GAAP EPS of -$0.32, beating expectations by $0.07, indicating improvements in financial management and increased market confidence.
  • Cash Position: As of December 31, 2025, the company had approximately $37.0 million in cash, cash equivalents, and restricted cash, demonstrating robust liquidity that supports future operations and investments.
  • Grant Funding Status: The remaining obligated grant funds from the National Institute of Aging total $35.7 million, providing crucial financial support for the company's R&D and enhancing its competitive position in the biopharmaceutical sector.
  • Funding Outlook: Cognition Therapeutics estimates that its current cash reserves are sufficient to fund operations and capital expenditures through the second quarter of 2027, indicating strong financial stability and growth potential over the next two years.
Newsfilter
9.0
03-26Newsfilter
Cognition Therapeutics Advances Zervimesine Clinical Development for DLB Psychosis
  • Clinical Development Plan: Cognition Therapeutics plans to meet with the FDA Division of Psychiatry in mid-2026 to align on the registrational plan for zervimesine in treating DLB psychosis, addressing a significant unmet need in this patient population and highlighting its market potential.
  • Trial Progress: The company has completed enrollment of 545 patients in the early Alzheimer's disease ‘START’ trial, with topline results expected in 2027, which will provide critical data for advancing zervimesine in Alzheimer's disease and potentially enhance its market acceptance.
  • Improved Financial Position: As of December 31, 2025, the company reported approximately $37 million in cash and cash equivalents, a significant increase from 2024, indicating effective cash management that supports operations through the second quarter of 2027.
  • Decrease in R&D Expenses: Research and development expenses for 2025 were $37.2 million, down from $41.7 million in 2024, primarily due to the completion of the SHINE and SHIMMER clinical trials, reflecting optimization in resource allocation.
moomoo
9.0
03-26moomoo
COGNITION THERAPEUTICS INC: FDA PSYCHIATRY DIVISION MEETING ANTICIPATED BY MID-2026
  • Cognition Therapeutics Meeting: Cognition Therapeutics is scheduled to meet with the FDA's Division of Psychiatry to discuss their developments and findings.

  • Timeline for Expectations: The meeting is anticipated to take place by mid-2026, indicating a timeline for potential advancements in their therapeutic approaches.

moomoo
9.5
03-26moomoo
Cognition Therapeutics Reports FY Operating Loss of USD 47.799 Million
  • Cognition Therapeutics Financial Update: The company reported an income of $47.799 million from its operations.
  • Operational Insights: The financial results indicate a significant revenue generation from the company's therapeutic initiatives.
Newsfilter
8.5
03-02Newsfilter
Cognition Advances Zervimesine Development for DLB Psychosis Treatment
  • FDA Meeting Outcome: Following the FDA meeting on January 21, 2026, Cognition Therapeutics has decided to pursue a registrational path for zervimesine to treat dementia with Lewy bodies (DLB) psychosis, which affects up to 75% of patients, potentially improving their quality of life and addressing a significant market gap.
  • SHIMMER Study Results: In the SHIMMER study, 130 adults with mild-to-moderate DLB received zervimesine, resulting in an 86% improvement in neuropsychiatric symptoms, indicating the drug's potential to enhance daily functioning and possibly transform the treatment landscape for DLB.
  • Clinical Trial Design: The next phase of the study will randomize participants to receive either 100mg of zervimesine or a placebo, focusing on measuring symptoms like hallucinations and delusions, which is expected to provide robust data for FDA discussions and expedite the drug's market entry.
  • Market Demand: With no approved medications for DLB psychosis and traditional antipsychotics potentially worsening motor function, the development of zervimesine not only meets a critical need but also presents a significant market opportunity for Cognition.
Newsfilter
8.5
02-05Newsfilter
Cognition Extends Expanded Access Program for DLB
  • Extended Access Program Duration: Cognition Therapeutics has announced an extension of the treatment duration for its Expanded Access Program (EAP) for dementia with Lewy bodies (DLB) from the original twelve months to several additional months, aimed at gathering more long-term safety data to enhance the reliability of clinical research.
  • Positive Patient Feedback: Since its launch in June 2025, the program has enrolled 32 participants, who have provided favorable feedback regarding their treatment experience, indicating strong recognition from patients and their caregivers, which may facilitate future patient recruitment.
  • Local Physician Involvement: By empowering local physicians to conduct routine health monitoring and allowing local laboratory testing, Cognition has effectively reduced travel burdens for patients, a strategy that not only enhances patient convenience but may also improve adherence and satisfaction levels among participants.
  • FDA Meeting Progress: Cognition held a meeting with the FDA on January 21, 2026, to discuss findings from the SHIMMER study and clinically meaningful endpoints for future research, with meeting minutes expected in February, which will provide crucial guidance for subsequent studies.
Wall Street analysts forecast CGTX stock price to rise
2 Analyst Rating
Wall Street analysts forecast CGTX stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
3.00
Averages
3.00
High
3.00
Current: 0.000
sliders
Low
3.00
Averages
3.00
High
3.00
B. Riley
B. Riley
Buy
maintain
$2 -> $3
AI Analysis
2025-11-21
Reason
B. Riley
B. Riley
Price Target
$2 -> $3
AI Analysis
2025-11-21
maintain
Buy
Reason
B. Riley raised the firm's price target on Cognition Therapeutics to $3 from $2 and keeps a Buy rating on the shares. Cognition's Phase 2 START trial for early Alzheimer's has fully enrolled 540 patients, reinforcing momentum from prior positive Phase 2b results and rising investigator interest in oral zervimesine, the analyst tells investors in a research note. With an 18-month primary endpoint and allowance for combination therapy, the trial design offers meaningful de-risking ahead of a mid-to-late 2027 readout, the firm adds.
H.C. Wainwright
Raghuram Selvaraju
Buy
downgrade
$5 -> $3
2025-05-27
Reason
H.C. Wainwright
Raghuram Selvaraju
Price Target
$5 -> $3
2025-05-27
downgrade
Buy
Reason
H.C. Wainwright analyst Raghuram Selvaraju lowered the firm's price target on Cognition Therapeutics to $3 from $5 and keeps a Buy rating on the shares. The firm cites the anticipated equity dilution later this year to extend the company's operational runway for the target cut. Zervimesine appears applicable across multiple fronts, the analyst tells investors in a research note.
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Valuation Metrics

The current forward P/E ratio for Cognition Therapeutics Inc (CGTX.O) is -5.64, compared to its 5-year average forward P/E of -2.74. For a more detailed relative valuation and DCF analysis to assess Cognition Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.74
Current PE
-5.64
Overvalued PE
-0.27
Undervalued PE
-5.22

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

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Frequently Asked Questions

What is Cognition Therapeutics Inc (CGTX) stock price today?

The current price of CGTX is 0.5946 USD — it has decreased -18.49

What is Cognition Therapeutics Inc (CGTX)'s business?

Cognition Therapeutics, Inc. is a clinical-stage biopharmaceutical company engaged in the discovery and development of small molecule therapeutics targeting age-related degenerative disorders of the central nervous system and retina. The Company is investigating its lead candidate, zervimesine (CT1812), in clinical programs in dementia with Lewy bodies (DLB) and Alzheimer’s disease. Its CT1812 and pipeline of sigma-2 modulators can regulate pathways that are impaired in these diseases for the treatment of degenerative diseases. Its lead product candidate, CT1812, is an orally delivered, small molecule designed to protect neuronal synapses by preventing the binding of oligomers of pathogenic proteins. Its pipeline candidates were discovered using proprietary biology and chemistry platforms designed to identify novel drug targets and disease-modifying therapies that address dysregulated pathways. It is developing other product candidates in the area of synucleinopathies.

What is the price predicton of CGTX Stock?

Wall Street analysts forecast CGTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CGTX is3.00 USD with a low forecast of 3.00 USD and a high forecast of 3.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Cognition Therapeutics Inc (CGTX)'s revenue for the last quarter?

Cognition Therapeutics Inc revenue for the last quarter amounts to -13.67M USD, increased 27.49

What is Cognition Therapeutics Inc (CGTX)'s earnings per share (EPS) for the last quarter?

Cognition Therapeutics Inc. EPS for the last quarter amounts to USD, decreased -100.00

How many employees does Cognition Therapeutics Inc (CGTX). have?

Cognition Therapeutics Inc (CGTX) has 14 emplpoyees as of March 31 2026.

What is Cognition Therapeutics Inc (CGTX) market cap?

Today CGTX has the market capitalization of 53.13M USD.