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CGTX Overview

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ET
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Intellectia

Loading chart...

High
1.180
Open
1.090
VWAP
1.13
Vol
839.49K
Mkt Cap
98.87M
Low
1.080
Amount
945.85K
EV/EBITDA(TTM)
--
Total Shares
88.27M
EV
56.00M
EV/OCF(TTM)
--
P/S(TTM)
--
Cognition Therapeutics, Inc. is a clinical-stage biopharmaceutical company engaged in the discovery and development of small molecule therapeutics targeting age-related degenerative disorders of the central nervous system and retina. The Company is investigating its lead candidate, zervimesine (CT1812), in clinical programs in dementia with Lewy bodies (DLB) and Alzheimer’s disease. Its CT1812 and pipeline of sigma-2 modulators can regulate pathways that are impaired in these diseases for the treatment of degenerative diseases. Its lead product candidate, CT1812, is an orally delivered, small molecule designed to protect neuronal synapses by preventing the binding of oligomers of pathogenic proteins. Its pipeline candidates were discovered using proprietary biology and chemistry platforms designed to identify novel drug targets and disease-modifying therapies that address dysregulated pathways. It is developing other product candidates in the area of synucleinopathies.
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Events Timeline

(ET)
2026-03-02
07:40:00
Cognition Therapeutics Advances Zervimesine Development
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2026-01-27 (ET)
2026-01-27
07:40:00
Cognition Therapeutics Holds Meeting with FDA to Discuss Zervimesine
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2026-01-06 (ET)
2026-01-06
07:40:00
Cognition Therapeutics Publishes Zervimesine Study Results
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2025-12-18 (ET)
2025-12-18
16:20:00
Cognition Therapeutics Files $300M Mixed Securities Shelf
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2025-12-01 (ET)
2025-12-01
07:40:00
Cognition Therapeutics Plans Registrational Program for Zervimesine in Alzheimer's Disease
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2025-11-13 (ET)
2025-11-13
07:38:20
Cognition Therapeutics finishes enrolling participants for Phase 2 trial of Zervimesine
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2025-11-06 (ET)
2025-11-06
07:38:33
Cognition Therapeutics Announces Q3 Earnings Per Share of 6 Cents, Below Consensus Estimate of 9 Cents
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News

Newsfilter
8.5
03-02Newsfilter
Cognition Advances Zervimesine Development for DLB Psychosis Treatment
  • FDA Meeting Outcome: Following the FDA meeting on January 21, 2026, Cognition Therapeutics has decided to pursue a registrational path for zervimesine to treat dementia with Lewy bodies (DLB) psychosis, which affects up to 75% of patients, potentially improving their quality of life and addressing a significant market gap.
  • SHIMMER Study Results: In the SHIMMER study, 130 adults with mild-to-moderate DLB received zervimesine, resulting in an 86% improvement in neuropsychiatric symptoms, indicating the drug's potential to enhance daily functioning and possibly transform the treatment landscape for DLB.
  • Clinical Trial Design: The next phase of the study will randomize participants to receive either 100mg of zervimesine or a placebo, focusing on measuring symptoms like hallucinations and delusions, which is expected to provide robust data for FDA discussions and expedite the drug's market entry.
  • Market Demand: With no approved medications for DLB psychosis and traditional antipsychotics potentially worsening motor function, the development of zervimesine not only meets a critical need but also presents a significant market opportunity for Cognition.
Newsfilter
8.5
02-05Newsfilter
Cognition Extends Expanded Access Program for DLB
  • Extended Access Program Duration: Cognition Therapeutics has announced an extension of the treatment duration for its Expanded Access Program (EAP) for dementia with Lewy bodies (DLB) from the original twelve months to several additional months, aimed at gathering more long-term safety data to enhance the reliability of clinical research.
  • Positive Patient Feedback: Since its launch in June 2025, the program has enrolled 32 participants, who have provided favorable feedback regarding their treatment experience, indicating strong recognition from patients and their caregivers, which may facilitate future patient recruitment.
  • Local Physician Involvement: By empowering local physicians to conduct routine health monitoring and allowing local laboratory testing, Cognition has effectively reduced travel burdens for patients, a strategy that not only enhances patient convenience but may also improve adherence and satisfaction levels among participants.
  • FDA Meeting Progress: Cognition held a meeting with the FDA on January 21, 2026, to discuss findings from the SHIMMER study and clinically meaningful endpoints for future research, with meeting minutes expected in February, which will provide crucial guidance for subsequent studies.
NASDAQ.COM
9.0
2025-12-17NASDAQ.COM
Post-Market Winners: A Calm Trading Day Highlighted by a Notable Biotech Rise
  • DBV Technologies Surge: DBV Technologies S.A. experienced a dramatic 61.29% increase in after-hours trading after announcing successful results from its Phase 3 study of the VIASKIN Peanut patch for peanut-allergic children, reigniting investor interest.

  • Modular Medical Offering: Modular Medical, Inc. saw a modest gain of 3.53% amid ongoing investor analysis of its recent public offering announcement, which includes over 12 million shares priced at an effective cost of $0.38 per share.

  • Other Small Gains: Several other companies, including Co-Diagnostics, Elutia Inc., and Treace Medical Concepts, posted small increases in after-hours trading, attributed to light-volume activity rather than specific news.

  • Amylyx Pharmaceuticals Update: Amylyx Pharmaceuticals advanced 4.83% following its recent presentation of early Phase 1 trial data for AMX0114, which showed promising safety and tolerability, with further enrollment expected soon.

NASDAQ.COM
2.0
2025-11-26NASDAQ.COM
Biotech and Healthcare Stocks Top After-Hours Gainers: ICU, CGTX, MESO, VRCA, AHCO
  • Biotech Gains in After-Hours Trading: Several small- and mid-cap biotech and healthcare companies saw significant gains in after-hours trading, driven by corporate updates and financing developments.

  • SeaStar Medical's Leadership Change: SeaStar Medical's stock rose nearly 10% after the appointment of Michael Messinger as Chief Financial Officer, boosting investor confidence despite no new news.

  • Cognition Therapeutics' Speculative Buying: Cognition Therapeutics rebounded almost 11% in after-hours trading, likely due to speculative buying interest, following a decline during regular trading hours.

  • Mesoblast's Revenue Projection: Mesoblast's shares increased after management projected over $30 million in gross revenue for the December quarter, indicating strong demand for its cell therapy product, Ryoncil.

Benzinga
6.0
2025-11-19Benzinga
HC Wainwright & Co. Affirms Buy Rating for Cognition Therapeutics, Keeps $3 Price Target Intact
  • Real-time Intelligence: Benzinga Pro offers the fastest news alerts for traders to stay updated on market movements.

  • Exclusive Content: Subscribers gain access to unique stories and insights generated by Benzinga reporters.

  • Community of Traders: Over 10,000 serious traders are part of the Benzinga Pro community, enhancing their trading strategies.

  • Market Winning Tools: The platform provides essential tools and information to help traders succeed in the stock market.

Newsfilter
9.0
2025-11-13Newsfilter
Cognition Therapeutics Finishes Participant Enrollment for Phase 2 Trial of Zervimesine (CT1812) in Early Alzheimer's Disease
  • Cognition Therapeutics' START Study Enrollment: Cognition Therapeutics has successfully enrolled 540 participants in its Phase 2 START Study, which evaluates the safety and efficacy of zervimesine (CT1812) for treating mild cognitive impairment and early Alzheimer's disease, with results expected after 18 months of treatment.

  • Collaboration and Support: The study is supported by an $81 million grant from the National Institute of Aging and conducted in partnership with the Alzheimer's Clinical Trials Consortium, highlighting the collaborative effort in Alzheimer's research.

  • Zervimesine's Unique Mechanism: Zervimesine is an investigational oral drug that targets neurodegenerative diseases by potentially interrupting the toxic effects of harmful proteins in the brain, offering a new treatment avenue for patients who do not respond to existing therapies.

  • Future Implications for Alzheimer's Treatment: The study aims to explore zervimesine's role in combination therapy for patients already receiving approved monoclonal antibody treatments, potentially expanding treatment options for a broader range of Alzheimer's patients.

Wall Street analysts forecast CGTX stock price to rise
2 Analyst Rating
Wall Street analysts forecast CGTX stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
3.00
Averages
3.00
High
3.00
Current: 0.000
sliders
Low
3.00
Averages
3.00
High
3.00
B. Riley
B. Riley
Buy
maintain
$2 -> $3
AI Analysis
2025-11-21
Reason
B. Riley
B. Riley
Price Target
$2 -> $3
AI Analysis
2025-11-21
maintain
Buy
Reason
B. Riley raised the firm's price target on Cognition Therapeutics to $3 from $2 and keeps a Buy rating on the shares. Cognition's Phase 2 START trial for early Alzheimer's has fully enrolled 540 patients, reinforcing momentum from prior positive Phase 2b results and rising investigator interest in oral zervimesine, the analyst tells investors in a research note. With an 18-month primary endpoint and allowance for combination therapy, the trial design offers meaningful de-risking ahead of a mid-to-late 2027 readout, the firm adds.
H.C. Wainwright
Raghuram Selvaraju
Buy
downgrade
$5 -> $3
2025-05-27
Reason
H.C. Wainwright
Raghuram Selvaraju
Price Target
$5 -> $3
2025-05-27
downgrade
Buy
Reason
H.C. Wainwright analyst Raghuram Selvaraju lowered the firm's price target on Cognition Therapeutics to $3 from $5 and keeps a Buy rating on the shares. The firm cites the anticipated equity dilution later this year to extend the company's operational runway for the target cut. Zervimesine appears applicable across multiple fronts, the analyst tells investors in a research note.
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Valuation Metrics

The current forward P/E ratio for Cognition Therapeutics Inc (CGTX.O) is -5.64, compared to its 5-year average forward P/E of -2.74. For a more detailed relative valuation and DCF analysis to assess Cognition Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.74
Current PE
-5.64
Overvalued PE
-0.27
Undervalued PE
-5.22

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

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CGTX
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Frequently Asked Questions

What is Cognition Therapeutics Inc (CGTX) stock price today?

The current price of CGTX is 1.12 USD — it has increased 3.7

What is Cognition Therapeutics Inc (CGTX)'s business?

Cognition Therapeutics, Inc. is a clinical-stage biopharmaceutical company engaged in the discovery and development of small molecule therapeutics targeting age-related degenerative disorders of the central nervous system and retina. The Company is investigating its lead candidate, zervimesine (CT1812), in clinical programs in dementia with Lewy bodies (DLB) and Alzheimer’s disease. Its CT1812 and pipeline of sigma-2 modulators can regulate pathways that are impaired in these diseases for the treatment of degenerative diseases. Its lead product candidate, CT1812, is an orally delivered, small molecule designed to protect neuronal synapses by preventing the binding of oligomers of pathogenic proteins. Its pipeline candidates were discovered using proprietary biology and chemistry platforms designed to identify novel drug targets and disease-modifying therapies that address dysregulated pathways. It is developing other product candidates in the area of synucleinopathies.

What is the price predicton of CGTX Stock?

Wall Street analysts forecast CGTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CGTX is3.00 USD with a low forecast of 3.00 USD and a high forecast of 3.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Cognition Therapeutics Inc (CGTX)'s revenue for the last quarter?

Cognition Therapeutics Inc revenue for the last quarter amounts to -6.38M USD, decreased -55.92

What is Cognition Therapeutics Inc (CGTX)'s earnings per share (EPS) for the last quarter?

Cognition Therapeutics Inc. EPS for the last quarter amounts to USD, decreased -100.00

How many employees does Cognition Therapeutics Inc (CGTX). have?

Cognition Therapeutics Inc (CGTX) has 25 emplpoyees as of March 11 2026.

What is Cognition Therapeutics Inc (CGTX) market cap?

Today CGTX has the market capitalization of 98.87M USD.