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BCAX Overview

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ET
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ET
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Intellectia

Loading chart...

High
21.990
Open
21.630
VWAP
21.69
Vol
348.67K
Mkt Cap
1.43B
Low
21.325
Amount
7.56M
EV/EBITDA(TTM)
--
Total Shares
65.70M
EV
889.31M
EV/OCF(TTM)
--
P/S(TTM)
--
Bicara Therapeutics Inc. is a clinical-stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Its lead program, ficerafusp alfa, is a bifunctional antibody that combines two clinically validated targets, an epidermal growth factor receptor (EGFR), directed monoclonal antibody with a domain that binds to human transforming growth factor beta (TGF-b). Through this dual-targeting mechanism, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer cell-intrinsic EGFR survival and proliferation and the immunosuppressive TGF-b signaling within the tumor microenvironment. Ficerafusp alfa is initially being developed in head and neck squamous cell carcinoma, where there remains a significant unmet need. Its platform is designed to facilitate the development of bifunctional therapies that precisely target the tumor and deliver a tumor-modulating payload to the tumor site.
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Events Timeline

(ET)
2026-05-11
08:20:00
Bicara Therapeutics Advances ficerafusp alfa for HPV-Negative Head and Neck Cancer
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2026-03-30 (ET)
2026-03-30
09:10:00
Stock Futures Modestly Higher as Oil Prices Surge Above $100
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News

Newsfilter
9.0
05-21Newsfilter
Bicara Therapeutics Reports New Data Showing Ficerafusp Alfa Significantly Improves Survival Rates
  • Significant Survival Improvement: At a three-year follow-up, the combination of 1500mg ficerafusp alfa with pembrolizumab demonstrated an overall survival rate of 31%, nearly doubling the rate observed with standard treatment, highlighting the therapy's potential in 1L R/M HPV-negative head and neck squamous cell carcinoma.
  • Durable Responses and Tolerability: Across all dose cohorts, the combination therapy achieved an 80% deep response rate with a generally well-tolerated safety profile and no new safety signals, indicating its feasibility for clinical application.
  • Clinical Data Validation: The complete response rates were 13%, 25%, and 30% for the 750mg, 1500mg, and 2000mg cohorts respectively, demonstrating a significant increase in efficacy with higher doses, further solidifying ficerafusp alfa's best-in-class status.
  • Future Research Plans: Bicara plans to initiate a new study in Q3 2026 to evaluate a 12-week loading dose followed by a 2250mg every-three-weeks maintenance regimen, showcasing the company's ongoing investment and confidence in the therapy's long-term effectiveness.
Fool
8.5
05-16Fool
Omega Fund Increases Stake in Bicara Therapeutics
  • Share Acquisition: Omega Fund disclosed a purchase of 187,500 shares of Bicara Therapeutics in an SEC filing dated May 15, 2026, with an estimated transaction value of $3.23 million, indicating strong confidence in the company's prospects.
  • Asset Allocation Shift: This acquisition raised Bicara's position to 29.16% of Omega Fund's reported assets, reflecting a highly concentrated investment strategy in the biotech sector that may influence future investment decisions.
  • Financial Overview: As of March 2026, Bicara reported $539.8 million in cash and marketable securities, sufficient to fund operations into the first half of 2029, despite a widening quarterly net loss of $56.2 million due to increased R&D spending.
  • Clinical Progress: Bicara is advancing its experimental therapy ficerafusp alfa for head and neck cancer, with management expecting substantial enrollment in the pivotal Phase 2/3 FORTIFI-HN01 study by year-end, showcasing its potential in oncology treatment.
Newsfilter
5.0
05-13Newsfilter
Bicara Therapeutics Appoints New CCO and Grants Stock Options
  • Executive Appointment: Bicara Therapeutics appointed Christopher Sarchi as Chief Commercial Officer effective May 8, 2026, granting him 282,240 stock options at an exercise price of $22.58 per share, reflecting the company's confidence in his potential to drive future performance.
  • Stock Option Structure: Sarchi's stock options will vest one-fourth on the first anniversary of his start date, with the remaining shares vesting in 12 equal quarterly installments, designed to incentivize his long-term commitment and alignment with the company's commercial objectives.
  • Independent Board Approval: The stock option grant was approved by Bicara's compensation committee, which consists solely of independent directors, ensuring transparency and compliance with Nasdaq Listing Rule 5635(c)(4), thereby reinforcing corporate governance standards.
  • Therapeutic Platform Development: Bicara is focused on developing bifunctional therapies, particularly its lead program ficerafusp alfa, which aims to enhance anti-tumor activity by simultaneously targeting EGFR and TGF-β, addressing significant unmet needs in solid tumors like head and neck squamous cell carcinoma.
NASDAQ.COM
2.0
05-11NASDAQ.COM
Bicara (BCAX) Q1 2026 Earnings Transcript
Newsfilter
9.5
05-11Newsfilter
Bicara Therapeutics Reports Q1 2026 Financial Results and Updates
  • Clinical Trial Progress: Bicara Therapeutics continues to advance the FORTIFI-HN01 pivotal trial in Q1 2026, expecting substantial enrollment by year-end to enable an interim analysis in mid-2027, paving the way for potential accelerated approval.
  • New Dosing Regimen Study: The company plans to initiate a randomized clinical study in Q3 2026 to evaluate a loading dose and every-three-week maintenance regimen of ficerafusp alfa in combination with pembrolizumab, aiming to further differentiate the therapy and expand options for patients and providers.
  • Executive Changes: Bill Schelman has been appointed Chief Medical Officer, succeeding David Raben, who transitions to a Senior Executive Advisor role, while Chris Sarchi is appointed Chief Commercial Officer, indicating the company's commitment to evolving into a commercial-stage entity.
  • Financial Performance: As of March 31, 2026, Bicara reported cash and cash equivalents of $539.8 million, a significant increase from $414.8 million at the end of 2025, while the net loss for Q1 2026 was $56.2 million, up from $36.8 million in the same period last year, reflecting ongoing investments in R&D.
Fool
5.0
05-04Fool
Bicara Therapeutics CMO Executes Stock Sale
  • Insider Stock Sale: David Raben, CMO of Bicara Therapeutics, sold 5,500 shares on April 27, 2026, for approximately $126,000, indicating active insider participation in the market.
  • Holding Change Analysis: The transaction reduced Raben's direct ownership by 9.05%, yet he retains 55,286 shares and 41,913 options, reflecting ongoing confidence in the company's future prospects.
  • Market Performance: As of April 27, 2026, Bicara's stock closed at $22.48, with a market cap of $1.4 billion; despite a reported net loss of $137.95 million in 2025, the stock has risen nearly 30% year-to-date, showcasing investor optimism for future growth.
  • Upcoming Earnings Report: Bicara is set to release its Q1 2026 financial results on May 11, with investors keenly awaiting insights into the company's ongoing development in the biopharmaceutical sector.
Wall Street analysts forecast BCAX stock price to rise
11 Analyst Rating
Wall Street analysts forecast BCAX stock price to rise
9 Buy
2 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
11.00
Averages
30.80
High
48.00
Current: 0.000
sliders
Low
11.00
Averages
30.80
High
48.00
Morgan Stanley
NULL -> Overweight
maintain
$36 -> $37
AI Analysis
2026-05-12
Reason
Morgan Stanley
Price Target
$36 -> $37
AI Analysis
2026-05-12
maintain
NULL -> Overweight
Reason
Morgan Stanley raised the firm's price target on Bicara Therapeutics to $37 from $36 and keeps an Overweight rating on the shares. The first quarter was focused on continued execution in FORTIFI-HN01, upcoming long-term Phase 1b data at ASCO, and further defining the development and commercial strategy for ficerafusp alfa, the analyst tells investors.
Goldman Sachs
Neutral
maintain
$16 -> $18
2026-05-12
Reason
Goldman Sachs
Price Target
$16 -> $18
2026-05-12
maintain
Neutral
Reason
Goldman Sachs raised the firm's price target on Bicara Therapeutics to $18 from $16 and keeps a Neutral rating on the shares. The firm updated its model following the Q1 earnings report.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for BCAX
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Valuation Metrics

The current forward P/E ratio for Bicara Therapeutics Inc (BCAX.O) is 0.00, compared to its 5-year average forward P/E of -7.50. For a more detailed relative valuation and DCF analysis to assess Bicara Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-7.50
Current PE
0.00
Overvalued PE
-3.95
Undervalued PE
-11.05

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.21
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.45
Undervalued EV/EBITDA
-6.86

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
Annual
Quarterly

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Whales Holding BCAX

A
Artal Group S.A.
Holding
BCAX
+11.24%
3M Return
T
TPG Capital, L.P.
Holding
BCAX
+11.07%
3M Return
V
Vestal Point Capital, LP
Holding
BCAX
+8.81%
3M Return
D
Deep Track Capital, LP
Holding
BCAX
+6.13%
3M Return
R
RA Capital Management, L.P.
Holding
BCAX
-3.23%
3M Return

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Frequently Asked Questions

What is Bicara Therapeutics Inc (BCAX) stock price today?

The current price of BCAX is 21.75 USD — it has increased 0

What is Bicara Therapeutics Inc (BCAX)'s business?

Bicara Therapeutics Inc. is a clinical-stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Its lead program, ficerafusp alfa, is a bifunctional antibody that combines two clinically validated targets, an epidermal growth factor receptor (EGFR), directed monoclonal antibody with a domain that binds to human transforming growth factor beta (TGF-b). Through this dual-targeting mechanism, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer cell-intrinsic EGFR survival and proliferation and the immunosuppressive TGF-b signaling within the tumor microenvironment. Ficerafusp alfa is initially being developed in head and neck squamous cell carcinoma, where there remains a significant unmet need. Its platform is designed to facilitate the development of bifunctional therapies that precisely target the tumor and deliver a tumor-modulating payload to the tumor site.

What is the price predicton of BCAX Stock?

Wall Street analysts forecast BCAX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for BCAX is30.80 USD with a low forecast of 11.00 USD and a high forecast of 48.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Bicara Therapeutics Inc (BCAX)'s revenue for the last quarter?

Bicara Therapeutics Inc revenue for the last quarter amounts to -60.24M USD, increased 44.16

What is Bicara Therapeutics Inc (BCAX)'s earnings per share (EPS) for the last quarter?

Bicara Therapeutics Inc. EPS for the last quarter amounts to -37568000.00 USD, increased 33.67

How many employees does Bicara Therapeutics Inc (BCAX). have?

Bicara Therapeutics Inc (BCAX) has 103 emplpoyees as of June 01 2026.

What is Bicara Therapeutics Inc (BCAX) market cap?

Today BCAX has the market capitalization of 1.43B USD.