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ET
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Intellectia

Loading chart...

High
20.240
Open
19.940
VWAP
19.95
Vol
390.01K
Mkt Cap
1.10B
Low
19.710
Amount
7.78M
EV/EBITDA(TTM)
--
Total Shares
54.78M
EV
977.50M
EV/OCF(TTM)
--
P/S(TTM)
--
Bicara Therapeutics Inc. is a clinical-stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Its lead program, ficerafusp alfa, is a bifunctional antibody that combines two clinically validated targets, an epidermal growth factor receptor (EGFR), directed monoclonal antibody with a domain that binds to human transforming growth factor beta (TGF-b). Through this dual-targeting mechanism, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer cell-intrinsic EGFR survival and proliferation and the immunosuppressive TGF-b signaling within the tumor microenvironment. Ficerafusp alfa is initially being developed in head and neck squamous cell carcinoma, where there remains a significant unmet need. Its platform is designed to facilitate the development of bifunctional therapies that precisely target the tumor and deliver a tumor-modulating payload to the tumor site.
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Events Timeline

(ET)
2026-03-04
08:40:00
Bicara Therapeutics Grants 115,000 Stock Options to New Employee
select
2026-02-24 (ET)
2026-02-24
16:20:00
Bicara Plans Common Stock Offering with Morgan Stanley as Joint Book-Running Manager
select
2026-02-05 (ET)
2026-02-05
08:40:00
Bicara Therapeutics Awards Inducement Stock Options to New Employees
select
2026-01-12 (ET)
2026-01-12
08:30:00
Bicara Therapeutics 2026 Corporate Outlook and Strategy
select
2025-12-07 (ET)
2025-12-07
13:10:00
Bicara Therapeutics Reports 57% Response Rate for 750mg Ficerafusp Alfa
select

News

Newsfilter
5.0
03-04Newsfilter
Bicara Therapeutics Grants Stock Options to New Employee
  • Stock Option Incentive: Bicara Therapeutics awarded a new employee 115,000 non-qualified stock options on March 2, 2026, with an exercise price of $17.59 per share, reflecting the company's commitment to attracting talent to strengthen its team for advancing clinical-stage bifunctional therapies.
  • Vesting Schedule: The stock options vest one-fourth on the employee's first anniversary and the remaining in 12 quarterly installments, ensuring continued service and enhancing employee commitment and stability within the company.
  • Independent Approval: The stock option grant was approved by Bicara's compensation committee, composed solely of independent directors, in accordance with Nasdaq Listing Rule 5635(c)(4), demonstrating transparency and compliance in corporate governance.
  • Commitment to Innovation: Bicara is focused on developing bifunctional antibodies like ficerafusp alfa for solid tumors such as head and neck squamous cell carcinoma, aiming to overcome barriers in the tumor microenvironment and address significant unmet medical needs, showcasing the company's innovative potential in the biopharmaceutical sector.
seekingalpha
8.5
02-25seekingalpha
Bicara Therapeutics Announces Public Offering Details
  • Offering Size: Bicara Therapeutics has priced a public offering of 7.175 million shares at $16 each, expecting to raise approximately $150 million before fees and expenses, indicating strong market demand and the company's financing capability.
  • Pre-Funded Warrants: The company is offering pre-funded warrants to purchase 2.2 million shares at $15.9999 each to select investors, enhancing investor flexibility and potentially attracting more capital inflow.
  • Underwriter Option: Bicara has granted underwriters a 30-day option to purchase up to 1,406,250 additional shares, a strategy that not only provides further financing opportunities but may also increase capital inflow if market demand is strong.
  • Market Reaction: Following the public offering announcement, BCAX shares rose 2.7% in premarket trading to $16.69, reflecting investor optimism about the company's prospects and potentially driving future stock performance.
Newsfilter
8.5
02-25Newsfilter
Bicara Therapeutics Prices Public Offering at $16.00 per Share
  • Offering Size: Bicara Therapeutics announced a public offering of 7,175,000 shares at $16.00 per share, expecting gross proceeds of approximately $150 million, indicating strong market demand for its biopharmaceutical products.
  • Pre-Funded Warrants: The company is also offering 2,200,000 pre-funded warrants at $15.9999 each, aimed at attracting more investors and further strengthening its capital structure.
  • Use of Proceeds: The funds will be utilized to support the regulatory filing and commercial launch of ficerafusp alfa, while accelerating its development in head and neck squamous cell carcinoma, demonstrating the company's commitment to new drug development.
  • Underwriter Lineup: With prominent financial institutions like Morgan Stanley, TD Cowen, and BofA Securities acting as joint book-running managers, confidence in the offering is bolstered, with the closing expected on February 26, 2026.
seekingalpha
8.5
02-24seekingalpha
Bicara Therapeutics Launches $150M Public Offering
  • Offering Size: Bicara Therapeutics has announced the commencement of a $150 million underwritten public offering, with a 30-day option for underwriters to purchase an additional $22.5 million in shares, reflecting the company's proactive approach to future financing.
  • Use of Proceeds: The funds raised will support regulatory and commercial preparations for ficerafusp alfa, accelerate its development in 1L R/M HPV-negative HNSCC, and finance manufacturing and early signal-finding for potential indication expansion, ensuring the company's competitiveness in the market.
  • Strategic Implications: This financing not only enhances Bicara's R&D capabilities but also lays the groundwork for future product launches, thereby improving the company's market position in the biopharmaceutical sector.
  • Market Reaction: The announcement of this public offering is likely to attract investor attention, especially against the backdrop of the company's commitment to innovative drug development, and is expected to have a positive impact on its stock price.
Newsfilter
9.0
02-19Newsfilter
Bicara Therapeutics Presents New Data on Ficerafusp Alfa Therapy
  • Significant Efficacy: At the 2026 Multidisciplinary Head and Neck Cancers Symposium, Bicara Therapeutics presented Phase 1b expansion cohort data showing a 48% confirmed overall response rate for 2000mg ficerafusp alfa combined with pembrolizumab, with 26% of patients achieving complete response and 77% of responders demonstrating over 80% tumor shrinkage, indicating deep and durable responses from the therapy.
  • Good Safety Profile: The safety profile of this regimen was consistent with the known safety of ficerafusp alfa plus pembrolizumab, suggesting that the 2000mg Q2W dosing scheme is well-tolerated, laying a solid foundation for future clinical applications.
  • New Dosing Regimen Development: Bicara plans to develop a loading and every-three-week maintenance regimen to optimize efficacy and safety, with expectations for regulatory alignment to facilitate potential U.S. approval, thereby expanding treatment options.
  • Ongoing Clinical Trials: Bicara is actively enrolling patients globally for the FORTIFI-HN01 pivotal study, continuing to evaluate the combination of 1500mg weekly ficerafusp alfa with pembrolizumab, aiming to provide more effective treatment solutions for head and neck cancer patients.
Globenewswire
9.0
2025-12-06Globenewswire
Bicara Therapeutics Reports Efficacy Data for 750mg Dose of Ficerafusp Alfa
  • Efficacy Data Presentation: At the ESMO Asia Congress, Bicara Therapeutics presented preliminary data showing a 57% confirmed overall response rate for 750mg ficerafusp alfa combined with pembrolizumab, with 10% of patients achieving a complete response, indicating significant potential for treating HPV-negative recurrent/metastatic head and neck squamous cell carcinoma.
  • Safety Analysis: The safety profile of the 750mg dose was consistent with the known safety of ficerafusp alfa plus pembrolizumab, demonstrating good tolerability in clinical applications and providing confidence for further research.
  • Dose Optimization Plan: Bicara plans to declare the optimal biologic dose for the FORTIFI-HN01 study in the first quarter of 2026, further advancing clinical trial progress and aiming to accelerate the approval process for this therapy.
  • TGF-β Inhibition Impact: Data from the 1500mg dose showed greater TGF-β inhibition, with a median depth of response of 82% compared to 63% for the 750mg dose, suggesting that higher doses may lead to more durable clinical outcomes, addressing the urgent need for effective treatments among patients.
Wall Street analysts forecast BCAX stock price to rise
11 Analyst Rating
Wall Street analysts forecast BCAX stock price to rise
9 Buy
2 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
11.00
Averages
30.80
High
48.00
Current: 0.000
sliders
Low
11.00
Averages
30.80
High
48.00
Goldman Sachs
Richard Law
Early-Stage Biotech -> Neutral
downgrade
$14
AI Analysis
2026-02-11
Reason
Goldman Sachs
Richard Law
Price Target
$14
AI Analysis
2026-02-11
downgrade
Early-Stage Biotech -> Neutral
Reason
Goldman Sachs analyst Richard Law moved shares of Bicara Therapeutics to Neutral rating and $14 price target from the firm's Early-Stage Biotech designation. The company's ficerafusp alfa combination is an improvement over the standard of care but unlikely has best-in-class potential, the analyst tells investors in a research note.
Citizens
initiated
$31
2026-01-29
Reason
Citizens
Price Target
$31
2026-01-29
initiated
Reason
Citizens initiated coverage of Bicara Therapeutics with an Outperform rating and $31 price target. The firm says the company's ficerafusp alfa, in combination with pembrolizumab, has delivered "standout efficacy" in HPV-negative head and neck squamous cell carcinoma. The analyst says Bicara shares represent an attractive investment opportunity, with 40% potential downside in a bear case and 210% potential upside in a bull case.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for BCAX
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Valuation Metrics

The current forward P/E ratio for Bicara Therapeutics Inc (BCAX.O) is -5.71, compared to its 5-year average forward P/E of -7.50. For a more detailed relative valuation and DCF analysis to assess Bicara Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-7.50
Current PE
-5.71
Overvalued PE
-3.95
Undervalued PE
-11.04

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.21
Current EV/EBITDA
-3.52
Overvalued EV/EBITDA
0.44
Undervalued EV/EBITDA
-6.86

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

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Quarterly

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Whales Holding BCAX

A
Artal Group S.A.
Holding
BCAX
+7.70%
3M Return
V
Vestal Point Capital, LP
Holding
BCAX
+6.94%
3M Return
R
RA Capital Management, L.P.
Holding
BCAX
+1.17%
3M Return
D
Deep Track Capital, LP
Holding
BCAX
-5.04%
3M Return
T
TPG Capital, L.P.
Holding
BCAX
-7.17%
3M Return

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Frequently Asked Questions

What is Bicara Therapeutics Inc (BCAX) stock price today?

The current price of BCAX is 19.9 USD — it has decreased -0.8

What is Bicara Therapeutics Inc (BCAX)'s business?

Bicara Therapeutics Inc. is a clinical-stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Its lead program, ficerafusp alfa, is a bifunctional antibody that combines two clinically validated targets, an epidermal growth factor receptor (EGFR), directed monoclonal antibody with a domain that binds to human transforming growth factor beta (TGF-b). Through this dual-targeting mechanism, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer cell-intrinsic EGFR survival and proliferation and the immunosuppressive TGF-b signaling within the tumor microenvironment. Ficerafusp alfa is initially being developed in head and neck squamous cell carcinoma, where there remains a significant unmet need. Its platform is designed to facilitate the development of bifunctional therapies that precisely target the tumor and deliver a tumor-modulating payload to the tumor site.

What is the price predicton of BCAX Stock?

Wall Street analysts forecast BCAX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for BCAX is30.80 USD with a low forecast of 11.00 USD and a high forecast of 48.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Bicara Therapeutics Inc (BCAX)'s revenue for the last quarter?

Bicara Therapeutics Inc revenue for the last quarter amounts to -40.68M USD, increased 97.19

What is Bicara Therapeutics Inc (BCAX)'s earnings per share (EPS) for the last quarter?

Bicara Therapeutics Inc. EPS for the last quarter amounts to -29290000.00 USD, increased 69.97

How many employees does Bicara Therapeutics Inc (BCAX). have?

Bicara Therapeutics Inc (BCAX) has 55 emplpoyees as of March 11 2026.

What is Bicara Therapeutics Inc (BCAX) market cap?

Today BCAX has the market capitalization of 1.10B USD.