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BBOT Overview

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0.000(0.000%)Aft-market
ET
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0.000
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ET
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Intellectia

Loading chart...

High
9.400
Open
8.970
VWAP
8.95
Vol
385.15K
Mkt Cap
702.69M
Low
8.660
Amount
3.45M
EV/EBITDA(TTM)
--
Total Shares
80.03M
EV
715.63M
EV/OCF(TTM)
--
P/S(TTM)
--
Bridgebio Oncology Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on advancing the pipeline of novel small molecule therapeutics targeting RAS and PI3Ka malignancies. Its pipeline of RAS-targeted oncology drug candidates includes BBO-8520, BBO-10203, and BBO-11818. BBO-8520 (NCT06343402) is a direct inhibitor of KRASG12C in both the ON and OFF states that is being evaluated both as monotherapy and in combination with pembrolizumab in the Phase 1 ONKORAS-101 trial for patients with KRASG12C mutant non-small cell lung cancer. BBO-10203 (NCT06625775) is an orally bioavailable small molecule that selectively and specifically blocks the physical interaction between RAS and PI3Ka, resulting in the inhibition of RAS-driven PI3Ka-AKT signaling in tumors without the risk of hyperglycemia. BBO-11818 (NCT06917079) is a panKRAS inhibitor targeting mutant KRAS in both the ON and OFF states with strong potency against KRASG12D and KRASG12V mutants.
Show More

Events Timeline

(ET)
2026-04-22
09:40:00
BridgeBio Oncology Appoints Pedro Beltran as CEO
select
2026-04-20 (ET)
2026-04-20
16:20:00
BridgeBio Oncology's BBO-11818 Receives FDA Fast Track Designation
select
2026-03-06 (ET)
2026-03-06
10:30:00
BridgeBio Announces Preclinical Data for BBO-11818
select
2026-01-07 (ET)
2026-01-07
07:10:00
BridgeBio Announces Positive Preliminary Antitumor Data Across Three Programs
select

News

seekingalpha
5.0
04-22seekingalpha
BridgeBio Appoints New CEO and COO
  • Executive Appointments: BridgeBio Oncology Therapeutics has appointed Pedro J. Beltran as CEO and Idan Elmelech as COO effective April 20, 2026, aiming to strengthen the company's leadership and strategic direction.
  • Experienced Leadership: Beltran brings approximately 20 years of oncology R&D experience from previous roles at Amgen and UNITY Biotechnology, which is expected to provide valuable industry insights and drive innovation within the company.
  • Former CEO's Advisory Role: Former CEO Eli Wallace will continue as a Senior Adviser, ensuring strategic consistency during the transition and leveraging his extensive experience to guide the new leadership team.
  • Financial Performance: BridgeBio Oncology reported a GAAP EPS of -$0.49, and despite facing financial challenges, the company is actively advancing its KRAS revolution plan, demonstrating confidence in future growth prospects.
Newsfilter
5.0
04-22Newsfilter
BBOT Appoints New CEO and COO to Drive Growth
  • Leadership Transition: Pedro J. Beltran, PhD, appointed as CEO on April 20, 2026, brings over 20 years of oncology drug development experience to steer BBOT's strategic growth in RAS and PI3Kα malignancies.
  • Operational Management Enhancement: Idan Elmelech takes on the role of COO, overseeing finance, corporate strategy, and business development, aiming to accelerate the expansion of BBOT's clinical assets through optimized operational efficiency.
  • Board Support: Neil Kumar, PhD, appointed as Executive Chairman, will guide the company into its next development phase, emphasizing that the leadership change will enhance the company's execution capabilities and strategic precision in clinical trials.
  • Former CEO's Continued Contribution: Former CEO Eli Wallace, PhD, will serve as a Senior Adviser, leveraging his scientific expertise to support BBOT's projects, ensuring the company's sustained development under new leadership.
NASDAQ.COM
9.0
04-21NASDAQ.COM
FDA Grants Fast Track Designation to BBO-11818 for Pancreatic Cancer
  • Fast Track Designation: BridgeBio Oncology Therapeutics' BBO-11818 has received Fast Track designation from the FDA for treating adults with advanced KRAS-mutant pancreatic ductal adenocarcinoma, marking a significant advancement in cancer therapy.
  • Preliminary Data Support: Preliminary data released in January 2026 indicated that BBO-11818 monotherapy showed a confirmed partial response in pancreatic cancer patients, highlighting its potential efficacy in treatment.
  • Observed Anti-Tumor Activity: Anti-tumor activity was observed across various dose levels and tumor types, particularly with tumor reductions at higher doses, indicating a favorable safety profile and offering new treatment options for patients.
  • Clinical Trial Progress: BBO-11818 is currently being evaluated in the Phase I KONQUER-101 trial for patients with locally advanced unresectable or metastatic KRAS-mutant solid tumors, with updated data expected in the second half of 2026 to further validate its clinical effectiveness.
seekingalpha
9.0
04-20seekingalpha
BridgeBio Oncology Receives FDA Fast Track Designation for BBO-11818
  • FDA Fast Track Designation: BridgeBio Oncology Therapeutics announced that its candidate BBO-11818 for advanced KRAS-mutant pancreatic ductal adenocarcinoma has received Fast Track designation from the US FDA, which is expected to accelerate its clinical development and enhance market competitiveness.
  • Clinical Trial Progress: BBO-11818 is currently in the KONQUER-101 trial, having enrolled patients with locally advanced unresectable or metastatic KRAS-mutant solid tumors, demonstrating promising early clinical responses that could provide new treatment options for patients.
  • Positive Preliminary Data: Preliminary data released in January indicated a confirmed partial response for BBO-11818, showcasing its strong activity in KRAS-mutant preclinical models, which may lay the groundwork for future clinical applications.
  • Positive Market Reaction: Following the announcement, BridgeBio's stock rose approximately 8% in after-hours trading, reflecting investor optimism regarding the drug's potential, which could drive future financing and R&D investments for the company.
Newsfilter
9.0
04-20Newsfilter
BBOT Receives FDA Fast Track Designation for BBO-11818
  • FDA Fast Track Designation: BBOT's BBO-11818 has received Fast Track designation from the FDA for its potential in treating advanced KRAS-mutant pancreatic ductal adenocarcinoma, which will expedite its development process to meet urgent patient needs for new therapies.
  • Clinical Trial Progress: Currently evaluated in the KONQUER-101 trial, updated clinical data for BBO-11818 is expected in the second half of 2026, showcasing its anti-tumor activity and safety profile in KRAS-mutant tumors.
  • Addressing Unmet Medical Needs: While KRASG12C inhibitors have shown clinical efficacy, there remains a significant unmet medical need for therapies targeting other KRAS mutations such as KRASG12D and KRASG12V, which BBO-11818 aims to address as a potent pan-KRAS inhibitor.
  • Multiple Treatment Regimens: BBO-11818 is being evaluated not only as a monotherapy but also in combination with standard-of-care therapies and BBOT's RAS:PI3Kα inhibitor BBO-10203, demonstrating its potential across various treatment combinations and enhancing its market competitiveness.
Newsfilter
8.5
03-06Newsfilter
BBO-11818: New KRAS Inhibitor Shows Promising Potential
  • Preclinical Data Release: BridgeBio Oncology Therapeutics (BBOT) published preclinical data on BBO-11818, demonstrating significant tumor growth inhibition in KRAS mutant models, particularly against KRASG12D and KRASG12V mutations, indicating its potential therapeutic value for KRAS-driven tumors.
  • Combination Therapy Potential: BBO-11818 shows enhanced efficacy when used in combination with other anti-tumor agents, such as BBO-10203, suggesting its importance in future treatment regimens and the potential to reshape existing treatment landscapes.
  • Clinical Trial Progress: Initial data from the KONQUER-101 trial indicate promising anti-tumor activity across various tumor types, including a 56% tumor reduction in a pancreatic cancer patient, with additional data expected in the second half of 2026.
  • Selectivity and Resistance: BBO-11818 exhibits over 500-fold selectivity for KRAS compared to other RAS isoforms, highlighting its potential to overcome resistance mechanisms associated with existing KRAS inhibitors, potentially offering better tolerability and therapeutic outcomes for patients.
Wall Street analysts forecast BBOT stock price to rise
6 Analyst Rating
Wall Street analysts forecast BBOT stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
18.00
Averages
22.83
High
27.00
Current: 0.000
sliders
Low
18.00
Averages
22.83
High
27.00
H.C. Wainwright
Buy
maintain
$27 -> $29
AI Analysis
2026-03-06
Reason
H.C. Wainwright
Price Target
$27 -> $29
AI Analysis
2026-03-06
maintain
Buy
Reason
H.C. Wainwright raised the firm's price target on BridgeBio Oncology to $29 from $27 and keeps a Buy rating on the shares. The firm updated the company's model post the Q4 report.
Stifel
Laura Prendergast
Buy
initiated
$23
2026-02-10
Reason
Stifel
Laura Prendergast
Price Target
$23
2026-02-10
initiated
Buy
Reason
Stifel analyst Laura Prendergast initiated coverage of BridgeBio Oncology with a Buy rating and $23 price target. The firm says the company is in the "sweet" spot by targeting RAS and PI3K alpha, the two most commonly mutated oncogenes. BridgeBio is well positioned into its second half of 2026 catalysts following January's "early de-risking data" and a cash runway into 2028, the analyst tells investors in a research note.
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Valuation Metrics

The current forward P/E ratio for BridgeBio Oncology Therapeutics Inc (BBOT.O) is 0.00, compared to its 5-year average forward P/E of -5.92. For a more detailed relative valuation and DCF analysis to assess BridgeBio Oncology Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.92
Current PE
0.00
Overvalued PE
-4.82
Undervalued PE
-7.02

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.21
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.60
Undervalued EV/EBITDA
-3.02

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
Annual
Quarterly

Whales Holding BBOT

P
Paradigm Biocapital Advisors LP
Holding
BBOT
+13.55%
3M Return
E
EcoR1 Capital, LLC
Holding
BBOT
+8.40%
3M Return
D
Deerfield Management Company, L.P.
Holding
BBOT
+4.44%
3M Return
C
Cormorant Asset Management, LP
Holding
BBOT
+0.10%
3M Return
C
Casdin Capital, LLC
Holding
BBOT
-8.64%
3M Return
N
Novo Holdings A/S
Holding
BBOT
-35.12%
3M Return

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Frequently Asked Questions

What is BridgeBio Oncology Therapeutics Inc (BBOT) stock price today?

The current price of BBOT is 8.78 USD — it has decreased -2.12

What is BridgeBio Oncology Therapeutics Inc (BBOT)'s business?

Bridgebio Oncology Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on advancing the pipeline of novel small molecule therapeutics targeting RAS and PI3Ka malignancies. Its pipeline of RAS-targeted oncology drug candidates includes BBO-8520, BBO-10203, and BBO-11818. BBO-8520 (NCT06343402) is a direct inhibitor of KRASG12C in both the ON and OFF states that is being evaluated both as monotherapy and in combination with pembrolizumab in the Phase 1 ONKORAS-101 trial for patients with KRASG12C mutant non-small cell lung cancer. BBO-10203 (NCT06625775) is an orally bioavailable small molecule that selectively and specifically blocks the physical interaction between RAS and PI3Ka, resulting in the inhibition of RAS-driven PI3Ka-AKT signaling in tumors without the risk of hyperglycemia. BBO-11818 (NCT06917079) is a panKRAS inhibitor targeting mutant KRAS in both the ON and OFF states with strong potency against KRASG12D and KRASG12V mutants.

What is the price predicton of BBOT Stock?

Wall Street analysts forecast BBOT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for BBOT is22.83 USD with a low forecast of 18.00 USD and a high forecast of 27.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is BridgeBio Oncology Therapeutics Inc (BBOT)'s revenue for the last quarter?

BridgeBio Oncology Therapeutics Inc revenue for the last quarter amounts to -1.16M USD, increased 403.98

What is BridgeBio Oncology Therapeutics Inc (BBOT)'s earnings per share (EPS) for the last quarter?

BridgeBio Oncology Therapeutics Inc. EPS for the last quarter amounts to USD, decreased -100.00

How many employees does BridgeBio Oncology Therapeutics Inc (BBOT). have?

BridgeBio Oncology Therapeutics Inc (BBOT) has 0 emplpoyees as of April 26 2026.

What is BridgeBio Oncology Therapeutics Inc (BBOT) market cap?

Today BBOT has the market capitalization of 702.69M USD.