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BBOT Overview

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ET
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Intellectia

Loading chart...

High
9.091
Open
8.800
VWAP
8.93
Vol
164.85K
Mkt Cap
713.09M
Low
8.800
Amount
1.47M
EV/EBITDA(TTM)
--
Total Shares
80.03M
EV
712.43M
EV/OCF(TTM)
--
P/S(TTM)
--
Bridgebio Oncology Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on advancing the pipeline of novel small molecule therapeutics targeting RAS and PI3Ka malignancies. Its pipeline of RAS-targeted oncology drug candidates includes BBO-8520, BBO-10203, and BBO-11818. BBO-8520 (NCT06343402) is a direct inhibitor of KRASG12C in both the ON and OFF states that is being evaluated both as monotherapy and in combination with pembrolizumab in the Phase 1 ONKORAS-101 trial for patients with KRASG12C mutant non-small cell lung cancer. BBO-10203 (NCT06625775) is an orally bioavailable small molecule that selectively and specifically blocks the physical interaction between RAS and PI3Ka, resulting in the inhibition of RAS-driven PI3Ka-AKT signaling in tumors without the risk of hyperglycemia. BBO-11818 (NCT06917079) is a panKRAS inhibitor targeting mutant KRAS in both the ON and OFF states with strong potency against KRASG12D and KRASG12V mutants.
Show More

Events Timeline

(ET)
2026-03-06
10:30:00
BridgeBio Announces Preclinical Data for BBO-11818
select
2026-01-07 (ET)
2026-01-07
07:10:00
BridgeBio Announces Positive Preliminary Antitumor Data Across Three Programs
select
2025-11-12 (ET)
2025-11-12
16:53:00
BridgeBio Oncology Announces Q3 EPS of $1.03, Exceeding Consensus Estimate of 34 Cents
select
2025-10-23 (ET)
2025-10-23
16:41:54
BridgeBio Oncology Reveals New Preclinical Findings from BBO-11818 Study
select

News

Newsfilter
8.5
03-06Newsfilter
BBO-11818: New KRAS Inhibitor Shows Promising Potential
  • Preclinical Data Release: BridgeBio Oncology Therapeutics (BBOT) published preclinical data on BBO-11818, demonstrating significant tumor growth inhibition in KRAS mutant models, particularly against KRASG12D and KRASG12V mutations, indicating its potential therapeutic value for KRAS-driven tumors.
  • Combination Therapy Potential: BBO-11818 shows enhanced efficacy when used in combination with other anti-tumor agents, such as BBO-10203, suggesting its importance in future treatment regimens and the potential to reshape existing treatment landscapes.
  • Clinical Trial Progress: Initial data from the KONQUER-101 trial indicate promising anti-tumor activity across various tumor types, including a 56% tumor reduction in a pancreatic cancer patient, with additional data expected in the second half of 2026.
  • Selectivity and Resistance: BBO-11818 exhibits over 500-fold selectivity for KRAS compared to other RAS isoforms, highlighting its potential to overcome resistance mechanisms associated with existing KRAS inhibitors, potentially offering better tolerability and therapeutic outcomes for patients.
seekingalpha
9.5
03-05seekingalpha
BridgeBio Oncology Reports Q4 2025 Financial Results and R&D Updates
  • Financial Performance: BridgeBio Oncology reported a GAAP EPS of -$0.49 for Q4 2025, indicating challenges in profitability; however, with cash and equivalents totaling $425.5 million, the company expects to sustain operations into 2028.
  • R&D Expense Increase: R&D expenses surged to $38.1 million in Q4 2025 from $19.5 million in Q4 2024, primarily driven by rising clinical trial and manufacturing costs for BBO-8520, BBO-11818, and BBO-10203, reflecting the company's commitment to drug development.
  • Administrative Costs Rise: General and administrative expenses reached $5.3 million in Q4 2025, up from $2.3 million in Q4 2024, indicating adjustments related to BBOT's standalone operations and the initiation of its de-SPAC transaction.
  • Net Loss Widening: The net loss for Q4 2025 was $38.8 million, nearly doubling from $19.7 million in Q4 2024, highlighting the financial pressures faced by the company as it expands its R&D and operational activities.
CNBC
6.0
02-11CNBC
Latest Rating Changes on Wall Street
  • Kingsoft Cloud Upgrade: Goldman Sachs upgrades Kingsoft Cloud (KC) from Neutral to Buy, citing the company's potential as a key beneficiary of Xiaomi's increased AI investments, which support its ambition to integrate AI with the physical world.
  • BridgeBio Initiation: Stifel initiates coverage of BridgeBio Oncology Therapeutics (BBOT) with a Buy rating and a $23 target price, indicating that the biotech company has significant room for growth in its stock price.
  • Energy Fuels Upgrade: Goldman Sachs upgrades Energy Fuels (UUUU) to Buy, highlighting its ownership of the highest-grade uranium deposit in the U.S. and the White Mesa Mill, which provides a competitive edge as the only facility capable of processing both uranium and rare earth elements.
  • James Hardie Upgrade: JPMorgan upgrades James Hardie Industries to Overweight from Neutral, noting that the outlook for U.S. residential new construction is in the early stages of recovery, and the stock trades at a discount to their blended price target, making it an attractive investment opportunity.
Globenewswire
1.0
2025-12-16Globenewswire
BridgeBio to Present Novel Therapeutics at 44th J.P. Morgan Healthcare Conference
  • Leadership Participation: BridgeBio Oncology Therapeutics will present at the 44th J.P. Morgan Healthcare Conference on January 12, 2026, at 5:15 p.m. PT, showcasing advancements in its RAS-pathway malignancy therapeutics, aimed at enhancing investor interest in the company's research direction.
  • Live Webcast Availability: The presentation will be accessible via a live webcast on BBOT's website, with a replay available for at least 90 days post-event, ensuring that investors unable to attend in real-time can still access critical information.
  • Company Background: BridgeBio is a clinical-stage biopharmaceutical company focused on advancing novel small molecule therapeutics targeting RAS and PI3Kα malignancies, with the goal of improving outcomes for patients with cancers driven by these two prevalent oncogenes.
  • Market Potential: By presenting its research advancements at a key healthcare conference, BridgeBio not only attracts potential investors' attention but also strengthens its position in the competitive biopharmaceutical market, further propelling the clinical development of its innovative drugs.
Newsfilter
1.0
2025-12-16Newsfilter
BridgeBio Oncology to Present Pipeline Advances at 44th J.P. Morgan Healthcare Conference
  • Leadership Participation: BridgeBio Oncology's leadership team will present at the 44th J.P. Morgan Healthcare Conference on January 12, 2026, at 5:15 p.m. PT, showcasing advancements in their RAS-pathway malignancies research, aimed at enhancing investor interest in the company's development direction.
  • Webcast Availability: The presentation will be live-streamed on BBOT's website under the 'Events' section, with a replay available for at least 90 days post-event, ensuring that investors unable to attend live can still access critical information, thereby enhancing transparency.
  • Clinical Stage Drug Development: BBOT focuses on advancing small molecule therapeutics targeting RAS and PI3Kα malignancies, aiming to improve outcomes for patients with cancers driven by these two prevalent oncogenes, demonstrating the company's potential in cancer treatment.
  • Investor Relations Enhancement: By participating in key healthcare conferences and providing online replays, BBOT not only strengthens its engagement with investors but also potentially attracts more funding focused on its innovative drug development, further propelling the company's growth in the biopharmaceutical sector.
Globenewswire
5.0
2025-12-11Globenewswire
BridgeBio Grants 53,060 Stock Options to New Employee as Inducement
  • Employee Incentive Plan: On December 10, 2025, BridgeBio awarded a new employee 53,060 non-qualified stock options at an exercise price of $12.88 per share under its 2025 Inducement Plan, aimed at attracting and retaining key talent to drive company growth.
  • Equity Incentive Structure: The stock options will vest 1/4 on the employee's first anniversary and in 36 equal monthly installments thereafter, ensuring continued service and contribution, which enhances team stability and execution capabilities.
  • Compliance Assurance: All stock options were granted outside of BBOT's stockholder-approved equity incentive plans, in accordance with Nasdaq Listing Rule 5635(c)(4), demonstrating the company's commitment to compliance and transparency in talent acquisition.
  • Strategic Company Positioning: As a clinical-stage biopharmaceutical company focused on RAS-pathway malignancies, BridgeBio aims to enhance the professionalism and innovation of its R&D team through such incentives, accelerating the development and market introduction of new therapeutics.
Wall Street analysts forecast BBOT stock price to rise
6 Analyst Rating
Wall Street analysts forecast BBOT stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
18.00
Averages
22.83
High
27.00
Current: 0.000
sliders
Low
18.00
Averages
22.83
High
27.00
H.C. Wainwright
Buy
maintain
$27 -> $29
AI Analysis
2026-03-06
Reason
H.C. Wainwright
Price Target
$27 -> $29
AI Analysis
2026-03-06
maintain
Buy
Reason
H.C. Wainwright raised the firm's price target on BridgeBio Oncology to $29 from $27 and keeps a Buy rating on the shares. The firm updated the company's model post the Q4 report.
Stifel
Laura Prendergast
Buy
initiated
$23
2026-02-10
Reason
Stifel
Laura Prendergast
Price Target
$23
2026-02-10
initiated
Buy
Reason
Stifel analyst Laura Prendergast initiated coverage of BridgeBio Oncology with a Buy rating and $23 price target. The firm says the company is in the "sweet" spot by targeting RAS and PI3K alpha, the two most commonly mutated oncogenes. BridgeBio is well positioned into its second half of 2026 catalysts following January's "early de-risking data" and a cash runway into 2028, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for BBOT
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Valuation Metrics

The current forward P/E ratio for BridgeBio Oncology Therapeutics Inc (BBOT.O) is 0.00, compared to its 5-year average forward P/E of -5.92. For a more detailed relative valuation and DCF analysis to assess BridgeBio Oncology Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.92
Current PE
0.00
Overvalued PE
-4.82
Undervalued PE
-7.02

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.21
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.60
Undervalued EV/EBITDA
-3.02

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
Annual
Quarterly

Whales Holding BBOT

P
Paradigm Biocapital Advisors LP
Holding
BBOT
+18.07%
3M Return
E
EcoR1 Capital, LLC
Holding
BBOT
+8.92%
3M Return
D
Deerfield Management Company, L.P.
Holding
BBOT
+6.03%
3M Return
C
Cormorant Asset Management, LP
Holding
BBOT
+3.64%
3M Return
N
Novo Holdings A/S
Holding
BBOT
-32.32%
3M Return

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Frequently Asked Questions

What is BridgeBio Oncology Therapeutics Inc (BBOT) stock price today?

The current price of BBOT is 8.91 USD — it has decreased -1.33

What is BridgeBio Oncology Therapeutics Inc (BBOT)'s business?

Bridgebio Oncology Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on advancing the pipeline of novel small molecule therapeutics targeting RAS and PI3Ka malignancies. Its pipeline of RAS-targeted oncology drug candidates includes BBO-8520, BBO-10203, and BBO-11818. BBO-8520 (NCT06343402) is a direct inhibitor of KRASG12C in both the ON and OFF states that is being evaluated both as monotherapy and in combination with pembrolizumab in the Phase 1 ONKORAS-101 trial for patients with KRASG12C mutant non-small cell lung cancer. BBO-10203 (NCT06625775) is an orally bioavailable small molecule that selectively and specifically blocks the physical interaction between RAS and PI3Ka, resulting in the inhibition of RAS-driven PI3Ka-AKT signaling in tumors without the risk of hyperglycemia. BBO-11818 (NCT06917079) is a panKRAS inhibitor targeting mutant KRAS in both the ON and OFF states with strong potency against KRASG12D and KRASG12V mutants.

What is the price predicton of BBOT Stock?

Wall Street analysts forecast BBOT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for BBOT is22.83 USD with a low forecast of 18.00 USD and a high forecast of 27.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is BridgeBio Oncology Therapeutics Inc (BBOT)'s revenue for the last quarter?

BridgeBio Oncology Therapeutics Inc revenue for the last quarter amounts to -1.16M USD, increased 403.98

What is BridgeBio Oncology Therapeutics Inc (BBOT)'s earnings per share (EPS) for the last quarter?

BridgeBio Oncology Therapeutics Inc. EPS for the last quarter amounts to USD, decreased -100.00

How many employees does BridgeBio Oncology Therapeutics Inc (BBOT). have?

BridgeBio Oncology Therapeutics Inc (BBOT) has 0 emplpoyees as of April 04 2026.

What is BridgeBio Oncology Therapeutics Inc (BBOT) market cap?

Today BBOT has the market capitalization of 713.09M USD.