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ANTX Overview

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Intellectia

Loading chart...

High
4.330
Open
4.100
VWAP
4.19
Vol
214.46K
Mkt Cap
66.52M
Low
4.030
Amount
897.87K
EV/EBITDA(TTM)
--
Total Shares
--
EV
-31.45M
EV/OCF(TTM)
--
P/S(TTM)
--
AN2 Therapeutics, Inc. is a biopharmaceutical company. The Company is focused on discovering and developing novel small molecule therapeutics derived from its boron chemistry platform. Its initial candidate is epetraborole, which is a potential once-daily, oral treatment with a novel mechanism of action for patients with non-tuberculous mycobacterial (NTM) lung disease, a rare, chronic, and progressive infectious disease caused by bacteria known as mycobacteria, which leads to irreversible lung damage and can be fatal. Epetraborole is designed to produce broad-spectrum antimycobacterial activity through inhibition of an essential and universal step in bacterial protein synthesis. Epetraborole is an investigational, boron-containing, orally bioavailable, small molecule inhibitor of bacterial leucyl-tRNA synthetase (LeuRS), an enzyme that catalyzes the attachment of leucine to transfer RNA (tRNA), molecules, an essential step in protein synthesis.
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Events Timeline

(ET)
2026-05-11
16:10:00
AN2 Therapeutics Raises $40 Million, Cash Runway Until 2029
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2026-04-09 (ET)
2026-04-09
17:30:00
AN2 Therapeutics Files $300M Mixed Securities Shelf
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2026-03-31 (ET)
2026-03-31
07:10:00
AN2 Therapeutics Initiates Lung Disease Clinical Trial
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2026-03-17 (ET)
2026-03-17
16:10:00
AN2 Therapeutics Advances Oral Drug to Phase 2 Study
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2026-03-03 (ET)
2026-03-03
16:10:00
AN2 Therapeutics Advances Oral Drug Development to Phase 2 Clinical Trial
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2026-01-12 (ET)
2026-01-12
07:20:00
AN2 Therapeutics Receives FDA Approval for Mycobacterium abscessus Study
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2025-11-12 (ET)
2025-11-12
16:03:36
AN2 Therapeutics Announces Q3 Earnings Per Share of 31 Cents, Exceeding Estimates of 22 Cents
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2025-11-10 (ET)
2025-11-10
07:18:56
AN2 Therapeutics and GSK Enter Tuberculosis Collaboration Agreement
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2025-08-12 (ET)
2025-08-12
16:02:04
AN2 Therapeutics reports Q2 EPS (21c) vs. (48c) last year
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News

seekingalpha
9.0
13:12 PMseekingalpha
AN2 Therapeutics Advances Chagas Disease Therapy
  • Clinical Trial Results: AN2 Therapeutics demonstrated significant efficacy of its experimental therapy AN2-502998 for Chagas disease in early studies, supporting its advancement into mid-stage development, with the potential to become the first FDA-approved therapy for chronic Chagas disease in adults.
  • Good Drug Tolerance: In the Phase 1 clinical trial, subjects exhibited good tolerance to AN2-502998, indicating potential safety and efficacy for future clinical applications.
  • Non-Human Primate Trials: In preclinical trials involving non-human primates, AN2-502998 completely eliminated T. cruzi parasites four months post-therapy, showcasing its potential in treating chronic Chagas disease.
  • Broad Market Potential: With Chagas disease affecting over 300,000 Americans, AN2 Therapeutics plans to launch a Phase 2 proof-of-concept study for AN2-502998 later this year, further advancing its commercialization efforts.
Newsfilter
9.0
11:40 AMNewsfilter
AN2 Therapeutics Reports Positive Results for Chagas Disease Treatment
  • Significant Efficacy: In nonhuman primates naturally infected with Trypanosoma cruzi, 28 days of AN2-502998 treatment resulted in 100% parasitic elimination, demonstrating the drug's effectiveness at exposure levels achievable in humans, indicating its potential for treating chronic Chagas disease.
  • Good Safety Profile: The Phase 1 clinical trial showed that AN2-502998 was well tolerated in healthy adults with no dose-limiting toxicities, suggesting a favorable safety profile that paves the way for future clinical applications and FDA approval.
  • Huge Market Opportunity: Chagas disease affects over 300,000 people in the U.S. and approximately 10 million globally, with AN2 Therapeutics estimating a multi-billion-dollar market potential for its treatment, particularly in the context of effective screening and low-cost diagnostics for high-risk populations.
  • Commitment to Global Access: AN2 Therapeutics is collaborating with DNDi to ensure that AN2-502998 is accessible in Chagas-endemic regions, which, if approved, will help address the long-standing unmet medical needs in this area.
moomoo
8.5
04-09moomoo
AN2 THERAPEUTICS INC. TO POTENTIALLY ISSUE UP TO $80 MILLION IN COMMON STOCK THROUGH AGREEMENT WITH JEFFERIES LLC, ACCORDING TO SEC FILING
  • Agreement Overview: Athera Therapeutics has entered into an agreement with Jefferies LLC for a common stock offering.

  • Financial Details: The offering could raise up to $80 million for Athera Therapeutics.

seekingalpha
9.5
03-17seekingalpha
AN2 Therapeutics Reports Q4 Earnings Miss
  • Earnings Report Disappointment: AN2 Therapeutics reported a Q4 GAAP EPS of -$0.29, missing the expected -$0.24, indicating challenges in profitability that could undermine investor confidence.
  • Cash Reserves Status: As of December 31, 2025, the company had cash, cash equivalents, and investments totaling $60 million, which, while providing some liquidity, raises concerns about capital efficiency and future financing needs.
  • Market Reaction Expectations: Given the earnings miss, the market may adopt a cautious stance regarding AN2's growth prospects, prompting investors to closely monitor subsequent strategic adjustments and financial health.
  • Analyst Rating Dynamics: According to Seeking Alpha's Quant Rating, AN2 Therapeutics' investment rating may be affected by its financial performance, leading analysts to potentially reassess its future investment value.
stocktwits
8.5
03-09stocktwits
AN2 Therapeutics Plans to Sell 8 Million Shares at $2.85 Each
  • Private Placement Announcement: AN2 Therapeutics plans to sell 8.25 million shares of common stock at $2.85 each, aiming to raise approximately $40 million, with participation from institutional investors like Coastlands Capital, Commodore Capital, and Vivo Capital, indicating strong market confidence in its blood cancer treatment.
  • Stock Surge: Following the announcement of positive clinical results for its blood cancer drug epetraborole, AN2 Therapeutics' stock has skyrocketed over 500% in four trading sessions, with a more than 110% increase on Monday alone, marking the largest single-day gain in its history and reflecting investor optimism about future developments.
  • Clinical Trial Progress: The company plans to initiate a Phase 2 clinical trial for patients with Polycythemia Vera in Q3 2026 and expects to provide initial trial updates in the following quarter, potentially validating the drug's efficacy and safety, which could enhance the company's market performance.
  • Market Sentiment Analysis: Retail sentiment on Stocktwits has remained extremely bullish over the past 24 hours, with high message volumes, as some users speculate the stock could rise to $108, although others express confusion over the bullish excitement, indicating mixed views in the market regarding the stock's future trajectory.
Benzinga
8.5
03-09Benzinga
AN2 Therapeutics Shares Surge After $40 Million Financing Announcement
  • Significant Financing: AN2 Therapeutics announced a $40 million private placement financing, selling 8,245,611 common shares at $2.85 each, along with pre-funded warrants, expected to close on March 10, significantly enhancing the company's financial strength to support R&D.
  • Strong Stock Performance: Following the financing announcement, AN2 Therapeutics shares surged 93.68% to $5.52, reaching a new 52-week high, indicating strong market confidence in the company's future and positive investor sentiment.
  • Diverse R&D Pipeline: AN2 Therapeutics is developing small molecule therapies based on its boron chemistry platform targeting various diseases, including polycythemia vera, nontuberculous mycobacterial lung disease, Chagas disease, and melioidosis, showcasing the company's broad focus in infectious and rare diseases.
  • Optimistic Market Outlook: With the successful financing, AN2 is poised to accelerate its R&D efforts, particularly in early-stage oncology and infectious disease research, further enhancing its competitiveness and market position in the biopharmaceutical industry.
Wall Street analysts forecast ANTX stock price to rise
4 Analyst Rating
Wall Street analysts forecast ANTX stock price to rise
1 Buy
2 Hold
1 Sell
Hold
Current: 0.000
sliders
Low
1.00
Averages
1.67
High
2.00
Current: 0.000
sliders
Low
1.00
Averages
1.67
High
2.00
Leerink
Joseph Schwartz
Market Perform
to
Outperform
upgrade
$9
AI Analysis
2026-05-14
Reason
Leerink
Joseph Schwartz
Price Target
$9
AI Analysis
2026-05-14
upgrade
Market Perform
to
Outperform
Reason
Leerink analyst Joseph Schwartz upgraded AN2 Therapeutics to Outperform from Market Perform with a $9 price target.

Valuation Metrics

The current forward P/E ratio for AN2 Therapeutics Inc (ANTX.O) is -1.41, compared to its 5-year average forward P/E of -3.06. For a more detailed relative valuation and DCF analysis to assess AN2 Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.06
Current PE
-1.41
Overvalued PE
-0.65
Undervalued PE
-5.47

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

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Frequently Asked Questions

What is AN2 Therapeutics Inc (ANTX) stock price today?

The current price of ANTX is 4.2 USD — it has increased 3.19

What is AN2 Therapeutics Inc (ANTX)'s business?

AN2 Therapeutics, Inc. is a biopharmaceutical company. The Company is focused on discovering and developing novel small molecule therapeutics derived from its boron chemistry platform. Its initial candidate is epetraborole, which is a potential once-daily, oral treatment with a novel mechanism of action for patients with non-tuberculous mycobacterial (NTM) lung disease, a rare, chronic, and progressive infectious disease caused by bacteria known as mycobacteria, which leads to irreversible lung damage and can be fatal. Epetraborole is designed to produce broad-spectrum antimycobacterial activity through inhibition of an essential and universal step in bacterial protein synthesis. Epetraborole is an investigational, boron-containing, orally bioavailable, small molecule inhibitor of bacterial leucyl-tRNA synthetase (LeuRS), an enzyme that catalyzes the attachment of leucine to transfer RNA (tRNA), molecules, an essential step in protein synthesis.

What is the price predicton of ANTX Stock?

Wall Street analysts forecast ANTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ANTX is1.67 USD with a low forecast of 1.00 USD and a high forecast of 2.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is AN2 Therapeutics Inc (ANTX)'s revenue for the last quarter?

AN2 Therapeutics Inc revenue for the last quarter amounts to -11.54M USD, decreased -36.94

What is AN2 Therapeutics Inc (ANTX)'s earnings per share (EPS) for the last quarter?

AN2 Therapeutics Inc. EPS for the last quarter amounts to -10624000.00 USD, decreased -39.61

How many employees does AN2 Therapeutics Inc (ANTX). have?

AN2 Therapeutics Inc (ANTX) has 22 emplpoyees as of June 04 2026.

What is AN2 Therapeutics Inc (ANTX) market cap?

Today ANTX has the market capitalization of 66.52M USD.