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ANRO Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
20.500
Open
19.970
VWAP
19.97
Vol
170.98K
Mkt Cap
704.34M
Low
19.330
Amount
3.41M
EV/EBITDA(TTM)
--
Total Shares
35.09M
EV
458.93M
EV/OCF(TTM)
--
P/S(TTM)
--
Alto Neuroscience, Inc. is a clinical-stage biopharmaceutical company focused on redefining psychiatry by leveraging neurobiology to develop personalized and effective treatment options. The Company's Precision Psychiatry Platform measures brain biomarkers by analyzing EEG activity, neurocognitive assessments, wearable data, and other factors to identify which patients are likely to respond to its product candidates. Its clinical-stage pipeline includes drug candidates in bipolar depression, major depressive disorder, treatment resistant depression (TRD), and schizophrenia, and other mental health conditions. Its product candidates include ALTO-100, ALTO-300, ALTO-207, ALTO-203, ALTO-101, ALTO-202, and ALTO-208. ALTO-100 is a first-in-class, oral small molecule believed to work through enhancing neural plasticity in the hippocampus, a brain region important for both cognition and mood. ALTO-203 is an oral small molecule histamine H3 receptor inverse agonist.
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Events Timeline

(ET)
2026-05-28
08:20:00
Alto Neuroscience Appoints Dr. Andrew Miller to Board of Directors
select
2026-05-13 (ET)
2026-05-13
07:10:00
Alto Neuroscience Initiates Phase 2b Trial of ALTO-207
select
2026-05-04 (ET)
2026-05-04
08:20:00
Alto Neuroscience Presents ALTO-207 Depression Trial Data
select
2026-04-21 (ET)
2026-04-21
08:30:00
Alto Neuroscience Initiates Phase 2b Trial of ALTO-207
select
2026-04-10 (ET)
2026-04-10
16:10:00
Alto Neuroscience Files to Sell 6M Shares of Common Stock
select

News

Newsfilter
8.5
05-15Newsfilter
Alto Neuroscience CEO Amit Etkin Receives Transformational Research Award
  • Leadership Recognition: Alto Neuroscience founder and CEO Amit Etkin, M.D., Ph.D., has been awarded the Transformational Research Award by the VP&S Alumni Association at Columbia University, highlighting his significant impact on the treatment of mental health disorders.
  • R&D Innovation: Dr. Etkin's Precision Psychiatry Platform™ aims to personalize mental health treatment by analyzing EEG, neurocognitive assessments, and wearable data to identify patients most likely to respond to specific therapies, potentially reshaping the industry.
  • Clinical Pipeline Development: Alto's clinical-stage pipeline includes programs for major depressive disorder, bipolar depression, treatment-resistant depression, and schizophrenia, with multiple mid- to late-stage data readouts expected over the next two years, which could significantly enhance the company's market position in biopharmaceuticals.
  • Academic-Industry Synergy: Dr. Etkin's academic background at Columbia University and collaboration with Nobel laureate Dr. Kandel have enabled him to bridge elite academic research with industrial innovation, driving fundamental changes in mental health treatment and showcasing a successful partnership between academia and industry.
seekingalpha
9.5
05-13seekingalpha
Alto Neuroscience Reports Q1 2026 Financial Results
  • Financial Performance: Alto Neuroscience reported a Q1 2026 GAAP EPS of -$0.80, indicating ongoing challenges in profitability and reflecting persistent financial pressure on the company.
  • Cash Position: As of March 31, 2026, the company had approximately $264.2 million in cash, cash equivalents, and restricted cash, a significant increase from $177.0 million as of December 31, 2025, primarily due to net proceeds of about $115 million from the March 2026 PIPE, although cash was still used in operations during the quarter.
  • Net Loss: The company incurred a net loss of $26.2 million for Q1 2026, compared to a net loss of $15.2 million for the same period in 2025, indicating a need for improved cost control and revenue generation efforts.
  • Financing Update: Alto Neuroscience recently announced a $120 million private placement financing, aimed at strengthening its capital base to support future research and operational activities.
CNBC
6.0
05-05CNBC
Major Wall Street Rating Updates
  • Chipotle Upgrade: Argus upgraded Chipotle Mexican Grill from Hold to Buy, indicating a return to growth, which reflects market optimism about the company's future performance.
  • Full Truck Alliance Initiation: Bank of America initiated coverage on Full Truck Alliance (FTA) with a Buy rating and a price target of $11.3, implying a 33% total return potential, showcasing confidence in its business model.
  • Alto Neuroscience Promising Outlook: Bank of America initiated coverage of Alto Neuroscience (ANRO) with a Buy rating and a $35 price target, emphasizing its innovative potential in treating psychiatric disorders, which may attract more investor interest.
  • Amazon Supply Chain Expansion: Bank of America reiterated its Buy rating on Amazon, highlighting the significant market potential of Amazon Supply Chain Services, which offers comprehensive logistics solutions for all businesses, further solidifying its market leadership.
NASDAQ.COM
4.5
04-02NASDAQ.COM
US Stocks Close Mixed Amid Oil Surge and Economic Data
  • Market Fluctuations: The S&P 500 Index closed up 0.11%, while the Dow Jones Industrial Average fell 0.13%, and the Nasdaq 100 Index rose 0.11%, reflecting volatility influenced by surging oil prices and economic data.
  • Positive Economic Data: Weekly initial unemployment claims unexpectedly fell by 9,000 to 202,000, indicating a stronger labor market than the anticipated increase to 212,000, which could impact the Fed's interest rate policy.
  • Impact of Oil Surge: Crude oil prices soared over 11% due to President Trump's tougher stance on Iran, leading to sharp declines in airline and cruise line stocks, with United Airlines and Carnival both down more than 3%.
  • Corporate Developments: SBA Communications surged over 18% as it explores potential acquisition options, while Globalstar rose over 13% amid reports of Amazon's interest in acquiring the company, highlighting market focus on M&A activity.
stocktwits
9.5
04-02stocktwits
Analysis of ALTO-101 Clinical Trial Failure Impact
  • ALTO-101 Trial Failure: Alto Neuroscience's ALTO-101 failed to meet key goals in its Phase 2 study, resulting in a 7% drop in stock price on Thursday, indicating weakened market confidence in its schizophrenia treatment and potential impacts on future funding capabilities.
  • Analyst Target Adjustments: Baird lowered Alto's price target from $41 to $38 while maintaining an 'Outperform' rating, emphasizing that the depression pipeline remains a key driver of the company's valuation, reflecting a reassessment of its potential value in the market.
  • Cash Reserves Support: H.C. Wainwright highlighted Alto's strong cash position of $275 million, which supports its other R&D projects despite the failure of ALTO-101, maintaining a 'Buy' rating and a $50 price target, demonstrating confidence in the company's long-term prospects.
  • Retail Sentiment Shift: Despite the stock's decline, retail investor sentiment on Stocktwits shifted from 'neutral' to 'bullish', indicating optimism about Alto's future potential, with the stock gaining over 20% year-to-date.
NASDAQ.COM
4.5
04-02NASDAQ.COM
Stock Markets Pressured by Soaring Oil Prices
  • Oil Price Surge Pressures Markets: Stock indexes are under pressure as crude oil prices soar over 8% following President Trump's aggressive stance on Iran, leading to a 0.06% drop in the S&P 500, a 0.23% decline in the Dow, and a 0.20% fall in the Nasdaq 100, indicating heightened inflation concerns among investors.
  • Unexpected Jobless Claims Drop: Despite market pressures, initial jobless claims fell by 9,000 to 202,000, indicating a stronger labor market than anticipated, which may provide some support for stocks and alleviate investor fears of an economic slowdown.
  • Divergent Energy Sector Performance: Energy producers like Diamondback Energy rose over 2% due to soaring WTI prices, while airline stocks such as American Airlines and Carnival fell more than 4% as rising fuel costs cut into profits, highlighting a clear divergence across sectors.
  • Tech Stocks Decline: Chipmakers and AI infrastructure stocks retreated, with ARM Holdings leading the Nasdaq 100 down over 5%, reflecting waning confidence in tech stocks and potentially impacting future investment decisions.
Wall Street analysts forecast ANRO stock price to rise
8 Analyst Rating
Wall Street analysts forecast ANRO stock price to rise
8 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
25.00
Averages
35.67
High
50.00
Current: 0.000
sliders
Low
25.00
Averages
35.67
High
50.00
Baird
Outperform
to
Outperform
downgrade
$38 -> $36
AI Analysis
2026-05-18
Reason
Baird
Price Target
$38 -> $36
AI Analysis
2026-05-18
downgrade
Outperform
to
Outperform
Reason
Baird lowered the firm's price target on Alto Neuroscience to $36 from $38 and keeps an Outperform rating on the shares. The firm updated its model following Q1 results.
Wedbush
Laura Chico
Neutral
maintain
$21 -> $24
2026-05-14
Reason
Wedbush
Laura Chico
Price Target
$21 -> $24
2026-05-14
maintain
Neutral
Reason
Wedbush analyst Laura Chico raised the firm's price target on Alto Neuroscience to $24 from $21 and keeps a Neutral rating on the shares. Most notable in the Q1 Alto's results, the company initiated the Phase 2b ALTO-207 study in treatment-resistant depression subjects, the firm notes. This is consistent with prior guidance and management anticipates top-line results by the second half of 2027.
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Valuation Metrics

The current forward P/E ratio for Alto Neuroscience Inc (ANRO.N) is 0.00, compared to its 5-year average forward P/E of -3.24. For a more detailed relative valuation and DCF analysis to assess Alto Neuroscience Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.24
Current PE
0.00
Overvalued PE
-1.13
Undervalued PE
-5.34

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.19
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.97
Undervalued EV/EBITDA
-1.36

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

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Quarterly

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Whales Holding ANRO

C
Commodore Capital LP
Holding
ANRO
+20.40%
3M Return
P
Perceptive Advisors LLC
Holding
ANRO
+10.32%
3M Return
V
Vestal Point Capital, LP
Holding
ANRO
+8.81%
3M Return
A
Armistice Capital LLC
Holding
ANRO
+6.75%
3M Return

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Frequently Asked Questions

What is Alto Neuroscience Inc (ANRO) stock price today?

The current price of ANRO is 20.07 USD — it has decreased -0.74

What is Alto Neuroscience Inc (ANRO)'s business?

Alto Neuroscience, Inc. is a clinical-stage biopharmaceutical company focused on redefining psychiatry by leveraging neurobiology to develop personalized and effective treatment options. The Company's Precision Psychiatry Platform measures brain biomarkers by analyzing EEG activity, neurocognitive assessments, wearable data, and other factors to identify which patients are likely to respond to its product candidates. Its clinical-stage pipeline includes drug candidates in bipolar depression, major depressive disorder, treatment resistant depression (TRD), and schizophrenia, and other mental health conditions. Its product candidates include ALTO-100, ALTO-300, ALTO-207, ALTO-203, ALTO-101, ALTO-202, and ALTO-208. ALTO-100 is a first-in-class, oral small molecule believed to work through enhancing neural plasticity in the hippocampus, a brain region important for both cognition and mood. ALTO-203 is an oral small molecule histamine H3 receptor inverse agonist.

What is the price predicton of ANRO Stock?

Wall Street analysts forecast ANRO stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ANRO is35.67 USD with a low forecast of 25.00 USD and a high forecast of 50.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Alto Neuroscience Inc (ANRO)'s revenue for the last quarter?

Alto Neuroscience Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Alto Neuroscience Inc (ANRO)'s earnings per share (EPS) for the last quarter?

Alto Neuroscience Inc. EPS for the last quarter amounts to -0.80 USD, increased 42.86

How many employees does Alto Neuroscience Inc (ANRO). have?

Alto Neuroscience Inc (ANRO) has 68 emplpoyees as of May 31 2026.

What is Alto Neuroscience Inc (ANRO) market cap?

Today ANRO has the market capitalization of 704.34M USD.