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ACHV Overview

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Intellectia

Loading chart...

High
4.220
Open
4.080
VWAP
4.14
Vol
2.59M
Mkt Cap
189.00M
Low
4.050
Amount
10.72M
EV/EBITDA(TTM)
--
Total Shares
53.24M
EV
167.49M
EV/OCF(TTM)
--
P/S(TTM)
--
Achieve Life Sciences, Inc. is a late-stage specialty pharmaceutical company. The Company focuses on addressing the global smoking health and nicotine dependence epidemic through the development and commercialization of cytisinicline. It has completed two Phase III studies with cytisinicline for smoking cessation and one Phase II study with cytisinicline in vaping cessation. Cytisinicline is a naturally occurring, plant-based alkaloid. Cytisinicline is structurally similar to nicotine and has a dual-acting mechanism of action, being both a receptor agonist and antagonist. Cytisinicline is an investigational product candidate being developed for the treatment of nicotine dependence and has not been approved by the Food and Drug Administration for any indication in the United States. Cytisinicline acts as a partial agonist/antagonist, binding to alpha-4 beta-2 nicotinic receptors in the brain and is thought to have two potential consequences in treating nicotine dependence.
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Events Timeline

(ET)
2026-04-16
09:10:00
New
Achieve Life Sciences Appoints Andrew Goldberg as CEO
select
2026-03-24 (ET)
2026-03-24
16:20:00
Major Averages Close Lower as Oil Surges Above $90
select
2026-03-24
12:00:00
Dow Jones Up 0.31% to 46,350.65 Points
select
2026-03-24
07:10:00
Achieve's Cash and Securities Reach $36.4 Million
select
2026-03-09 (ET)
2026-03-09
16:50:00
Aeon Biopharma Appoints John Bencich as CFO
select
2026-01-23 (ET)
2026-01-23
16:10:00
Achieve Life Sciences Files $300M Mixed Securities Shelf
select
2026-01-12 (ET)
2026-01-12
09:00:00
Achieve Life Sciences Appoints Mark Rubinstein as Chief Medical Officer
select

News

seekingalpha
8.5
13:12 PMseekingalpha
PinnedAchieve Life Sciences Secures $354 Million Financing for Drug Development
  • Significant Financing: Achieve Life Sciences announced a securities purchase agreement that could raise up to $354 million in gross proceeds, including an upfront investment of approximately $180 million, providing substantial financial backing for the company's future initiatives.
  • Clear Use of Funds: The proceeds will fund a Phase 3 trial for its smoking cessation drug candidate cytisinicline, support commercialization efforts in the e-cigarette market, and cover general corporate purposes, thereby enhancing the company's competitive position and product development capabilities.
  • Milestone-Based Incentives: The financing agreement includes up to an additional $174 million tied to the exercise of milestone-based warrants, reflecting investor confidence in ACHV's future growth and the potential of its product offerings.
  • Transaction Timeline: The private placement is expected to close on April 17, subject to customary conditions, providing a clear timeline for the infusion of capital that will accelerate clinical trials and market launch efforts.
Newsfilter
8.5
03-26Newsfilter
Achieve Life Sciences Publishes New Study on Cytisinicline
  • Significant Research Findings: Achieve Life Sciences' study published in Nicotine & Tobacco Research reveals that cytisinicline demonstrates a 99% binding affinity at the α4β2 nicotinic receptor, indicating its effectiveness and potential in smoking cessation therapy.
  • Tolerability Advantage: The study shows minimal binding (-8% displacement) to the 5-HT3 receptor, which helps explain the low incidence of adverse effects like nausea observed in clinical trials, potentially appealing to more smokers looking to quit.
  • Urgent Market Demand: With approximately 25 million adults smoking and 18 million vaping in the U.S., and over half wanting to quit, there is a strong demand for new treatment options, making the development of cytisinicline timely and relevant.
  • Regulatory Progress: Achieve Life Sciences has submitted a New Drug Application to the FDA, with a review date set for June 20, 2026, laying the groundwork for cytisinicline's market introduction and potentially transforming the landscape of smoking cessation therapies.
seekingalpha
9.5
03-24seekingalpha
Achieve Life Sciences Q4 2025 Earnings Call Insights
  • Clinical Transition Progress: Achieve Life Sciences submitted the NDA for cytisinicline in June 2025, marking a shift from clinical to commercial focus, aiming to provide treatment for 25 million smokers and nearly 18 million vapers, demonstrating the company's keen awareness of market demand.
  • Regulatory Milestone Achieved: The FDA accepted the NDA for cytisinicline and granted a National Priority Voucher for the vaping indication, providing an accelerated pathway to potential first-in-class approval for vaping cessation, which holds significant market potential.
  • Financial Status Update: As of December 31, 2025, the company reported $36.4 million in cash and cash equivalents, with operating expenses of $14.7 million and a net loss of $14.7 million, reflecting ongoing investments in regulatory and commercial preparations despite a cash decrease from the previous quarter.
  • Market Readiness and Risk Management: Management has engaged with payers approximately 40 times, emphasizing the differentiated profile of cytisinicline and the unmet market needs, while planning to initiate the ORCA-V2 Phase III trial in vaping cessation in the first half of 2026, showcasing the company's strategic focus on market access and supply chain security.
seekingalpha
8.0
03-24seekingalpha
Iran Allows 'Non-Hostile' Vessels to Transit Strait of Hormuz
  • Transit Policy: Iran informed the International Maritime Organization that 'non-hostile' vessels may pass through the Strait of Hormuz if they coordinate with Iranian authorities, aiming to alleviate the shipping crisis caused by ongoing conflicts.
  • Shipping Disruption Impact: Since the conflict erupted on February 28, shipping through the Strait has nearly ceased, leaving approximately 3,200 vessels stranded in the Gulf, affecting 20% of global oil shipments and trade for Gulf nations.
  • Transit Costs: Some shipping operators have reportedly paid up to $2 million to secure safe passage, reflecting the significant impact of the current situation on shipping costs and operational risks.
  • Humanitarian Corridor Exploration: The International Maritime Organization is considering establishing a humanitarian corridor to allow vessels facing fuel or supply shortages to safely exit the region, highlighting the importance of maritime safety amidst escalating tensions.
seekingalpha
9.5
03-24seekingalpha
Achieve Life Sciences Q4 Earnings Miss Expectations
  • Earnings Performance: Achieve Life Sciences reported a Q4 GAAP EPS of -$0.28, missing expectations by $0.01, indicating challenges in profitability that could impact investor confidence moving forward.
  • Cash Reserves Status: As of December 31, 2025, the company held $36.4 million in cash, cash equivalents, and marketable securities, which, while providing some liquidity, raises concerns about capital efficiency and future funding needs.
  • Market Outlook Analysis: The company is viewed as a potential 'best tobacco stock' for 2026, bolstered by endorsement from Hunterbrook Capital, suggesting market anticipation for its upcoming product Cytisinicline, which may lead to stock price volatility.
  • Ratings and Analysis: Seeking Alpha's Quant Rating assigns a Strong Buy to Achieve Life Sciences, reflecting analysts' optimism about the company's growth potential despite its current financial performance.
moomoo
9.5
03-24moomoo
ACHIEVE LIFE SCIENCES INC REPORTS Q4 NET LOSS OF $14.7 MILLION, FY2025 NET LOSS TOTALS $54.7 MILLION
  • Q4 Financial Performance: The company reported a net loss of $14.7 million for the fourth quarter.

  • FY 2025 Projections: For the fiscal year 2025, the projected net loss is $54.7 million.

Wall Street analysts forecast ACHV stock price to rise
2 Analyst Rating
Wall Street analysts forecast ACHV stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
12.00
Averages
15.50
High
19.00
Current: 0.000
sliders
Low
12.00
Averages
15.50
High
19.00
H.C. Wainwright
H.C. Wainwright
maintain
$12
AI Analysis
2026-02-06
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$12
AI Analysis
2026-02-06
maintain
Reason
H.C. Wainwright views Pfizer's (PFE) launch of Chantix among the 30 medicines it placed on the White House's direct-to-consumer site, TrumpRx, as "a significant positive" for Achieve Life Sciences (ACHV) and cytisinicline, arguing that the news removes the potential of Pfizer bringing Chantix back to market and putting any marketing dollars behind the product. The move to include Chantix on TrumpRx is "not random or economically driven," but rather likely a concession to the Make America Healthy Movement within the current administration, which bodes well for the potential for cytisinicline's chances of approval by the current PDUFA date on June 20, adds the analyst, who has a Buy rating and $12 price target on Achieve shares.
JMP
Jason Butler
Outperform
initiated
$19
2025-11-25
Reason
JMP
Jason Butler
Price Target
$19
2025-11-25
initiated
Outperform
Reason
Citizens JMP analyst Jason Butler initiated coverage of Achieve Life Sciences with an Outperform rating and $19 price target. Achieve is developing cytisinicline, a nicotine dependence treatment for smoking cessation in adults, the analyst tells investors in a research note. The firm believes cytisinicline has a "highly differentiated" profile to Chantix and can both supplant and grow the current market.
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Valuation Metrics

The current forward P/E ratio for Achieve Life Sciences Inc (ACHV.O) is 35.34, compared to its 5-year average forward P/E of 0.49. For a more detailed relative valuation and DCF analysis to assess Achieve Life Sciences Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
0.49
Current PE
35.34
Overvalued PE
14.41
Undervalued PE
-13.44

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.23
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.30
Undervalued EV/EBITDA
-0.75

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
73.04
Current PS
5.07
Overvalued PS
288.39
Undervalued PS
-142.31

Financials

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Frequently Asked Questions

What is Achieve Life Sciences Inc (ACHV) stock price today?

The current price of ACHV is 4.1423 USD — it has increased 16.68

What is Achieve Life Sciences Inc (ACHV)'s business?

Achieve Life Sciences, Inc. is a late-stage specialty pharmaceutical company. The Company focuses on addressing the global smoking health and nicotine dependence epidemic through the development and commercialization of cytisinicline. It has completed two Phase III studies with cytisinicline for smoking cessation and one Phase II study with cytisinicline in vaping cessation. Cytisinicline is a naturally occurring, plant-based alkaloid. Cytisinicline is structurally similar to nicotine and has a dual-acting mechanism of action, being both a receptor agonist and antagonist. Cytisinicline is an investigational product candidate being developed for the treatment of nicotine dependence and has not been approved by the Food and Drug Administration for any indication in the United States. Cytisinicline acts as a partial agonist/antagonist, binding to alpha-4 beta-2 nicotinic receptors in the brain and is thought to have two potential consequences in treating nicotine dependence.

What is the price predicton of ACHV Stock?

Wall Street analysts forecast ACHV stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ACHV is15.50 USD with a low forecast of 12.00 USD and a high forecast of 19.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Achieve Life Sciences Inc (ACHV)'s revenue for the last quarter?

Achieve Life Sciences Inc revenue for the last quarter amounts to -14.73M USD, increased 20.84

What is Achieve Life Sciences Inc (ACHV)'s earnings per share (EPS) for the last quarter?

Achieve Life Sciences Inc. EPS for the last quarter amounts to -17980000.00 USD, increased 95.67

How many employees does Achieve Life Sciences Inc (ACHV). have?

Achieve Life Sciences Inc (ACHV) has 28 emplpoyees as of April 16 2026.

What is Achieve Life Sciences Inc (ACHV) market cap?

Today ACHV has the market capitalization of 189.00M USD.