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ACHV Overview

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0.000(0.000%)Aft-market
ET
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0.000
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ET
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Intellectia

Loading chart...

High
4.895
Open
4.590
VWAP
4.70
Vol
1.29M
Mkt Cap
492.76M
Low
4.408
Amount
6.06M
EV/EBITDA(TTM)
--
Total Shares
102.66M
EV
471.25M
EV/OCF(TTM)
--
P/S(TTM)
--
Achieve Life Sciences, Inc. is a late-stage specialty pharmaceutical company. The Company focuses on addressing the global smoking health and nicotine dependence epidemic through the development and commercialization of cytisinicline. It has completed two Phase III studies with cytisinicline for smoking cessation and one Phase II study with cytisinicline in vaping cessation. Cytisinicline is a naturally occurring, plant-based alkaloid. Cytisinicline is structurally similar to nicotine and has a dual-acting mechanism of action, being both a receptor agonist and antagonist. Cytisinicline is an investigational product candidate being developed for the treatment of nicotine dependence and has not been approved by the Food and Drug Administration for any indication in the United States. Cytisinicline acts as a partial agonist/antagonist, binding to alpha-4 beta-2 nicotinic receptors in the brain and is thought to have two potential consequences in treating nicotine dependence.
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Events Timeline

(ET)
2026-04-16
11:00:00
Achieve Life Sciences Completes $354M Private Placement
select
2026-04-16
09:10:00
Achieve Life Sciences Appoints Andrew Goldberg as CEO
select
2026-03-24 (ET)
2026-03-24
16:20:00
Major Averages Close Lower as Oil Surges Above $90
select
2026-03-24
12:00:00
Dow Jones Up 0.31% to 46,350.65 Points
select
2026-03-24
07:10:00
Achieve's Cash and Securities Reach $36.4 Million
select
2026-03-09 (ET)
2026-03-09
16:50:00
Aeon Biopharma Appoints John Bencich as CFO
select

News

Newsfilter
9.5
05-05Newsfilter
PinnedAchieve Life Sciences to Report Q1 2026 Financial Results on May 12
  • Earnings Announcement: Achieve Life Sciences will report its Q1 2026 financial results and provide a corporate update on May 12, 2026, at 8:30 AM EDT, which is expected to positively influence investor confidence.
  • FDA Review Progress: The New Drug Application for cytisinicline submitted in June 2025 has been accepted for review by the FDA, with a PDUFA date set for June 20, 2026, paving the way for potential market launch.
  • Market Demand Context: Approximately 25 million adults in the U.S. smoke, with tobacco use causing over 500,000 deaths annually, highlighting the urgent need for effective smoking cessation treatments, which cytisinicline aims to address.
  • Clinical Research Outcomes: Cytisinicline has completed multiple clinical studies for smoking and vaping cessation, with successful Phase 3 results laying a strong foundation for future commercialization, potentially enhancing the company's competitive position in the market.
stocktwits
5.0
04-16stocktwits
Achieve Appoints New CEO and Secures $354 Million Funding
  • New CEO Appointment: Achieve Life Sciences appointed Andrew D. Goldberg as CEO and Board member on Monday, who previously served as a Portfolio Manager at Marshall Wace, aiming to drive strategic transformation and enhance market competitiveness.
  • Funding Agreement Secured: The company entered into a securities purchase agreement with leading healthcare investors, expected to raise up to approximately $354 million through a private placement, including about $180 million in initial funding, which will support clinical trials and working capital.
  • Near-Term Milestones: Achieve anticipates launching cytisinicline for nicotine dependence in the first half of 2027; despite the FDA's potential rejection of its current application by June 20, the company plans to resubmit in Q4 2026, indicating confidence in future market prospects.
  • Investor Sentiment Surge: On Stocktwits, retail sentiment around ACHV stock remains in the 'extremely bullish' territory, with message volume increasing from 'normal' to 'high', reflecting optimistic expectations among investors regarding potential acquisition opportunities post-drug approval.
seekingalpha
8.5
04-16seekingalpha
Achieve Life Sciences Secures $354 Million Financing for Drug Development
  • Significant Financing: Achieve Life Sciences announced a securities purchase agreement that could raise up to $354 million in gross proceeds, including an upfront investment of approximately $180 million, providing substantial financial backing for the company's future initiatives.
  • Clear Use of Funds: The proceeds will fund a Phase 3 trial for its smoking cessation drug candidate cytisinicline, support commercialization efforts in the e-cigarette market, and cover general corporate purposes, thereby enhancing the company's competitive position and product development capabilities.
  • Milestone-Based Incentives: The financing agreement includes up to an additional $174 million tied to the exercise of milestone-based warrants, reflecting investor confidence in ACHV's future growth and the potential of its product offerings.
  • Transaction Timeline: The private placement is expected to close on April 17, subject to customary conditions, providing a clear timeline for the infusion of capital that will accelerate clinical trials and market launch efforts.
Newsfilter
8.5
03-26Newsfilter
Achieve Life Sciences Publishes New Study on Cytisinicline
  • Significant Research Findings: Achieve Life Sciences' study published in Nicotine & Tobacco Research reveals that cytisinicline demonstrates a 99% binding affinity at the α4β2 nicotinic receptor, indicating its effectiveness and potential in smoking cessation therapy.
  • Tolerability Advantage: The study shows minimal binding (-8% displacement) to the 5-HT3 receptor, which helps explain the low incidence of adverse effects like nausea observed in clinical trials, potentially appealing to more smokers looking to quit.
  • Urgent Market Demand: With approximately 25 million adults smoking and 18 million vaping in the U.S., and over half wanting to quit, there is a strong demand for new treatment options, making the development of cytisinicline timely and relevant.
  • Regulatory Progress: Achieve Life Sciences has submitted a New Drug Application to the FDA, with a review date set for June 20, 2026, laying the groundwork for cytisinicline's market introduction and potentially transforming the landscape of smoking cessation therapies.
seekingalpha
9.5
03-24seekingalpha
Achieve Life Sciences Q4 2025 Earnings Call Insights
  • Clinical Transition Progress: Achieve Life Sciences submitted the NDA for cytisinicline in June 2025, marking a shift from clinical to commercial focus, aiming to provide treatment for 25 million smokers and nearly 18 million vapers, demonstrating the company's keen awareness of market demand.
  • Regulatory Milestone Achieved: The FDA accepted the NDA for cytisinicline and granted a National Priority Voucher for the vaping indication, providing an accelerated pathway to potential first-in-class approval for vaping cessation, which holds significant market potential.
  • Financial Status Update: As of December 31, 2025, the company reported $36.4 million in cash and cash equivalents, with operating expenses of $14.7 million and a net loss of $14.7 million, reflecting ongoing investments in regulatory and commercial preparations despite a cash decrease from the previous quarter.
  • Market Readiness and Risk Management: Management has engaged with payers approximately 40 times, emphasizing the differentiated profile of cytisinicline and the unmet market needs, while planning to initiate the ORCA-V2 Phase III trial in vaping cessation in the first half of 2026, showcasing the company's strategic focus on market access and supply chain security.
seekingalpha
8.0
03-24seekingalpha
Iran Allows 'Non-Hostile' Vessels to Transit Strait of Hormuz
  • Transit Policy: Iran informed the International Maritime Organization that 'non-hostile' vessels may pass through the Strait of Hormuz if they coordinate with Iranian authorities, aiming to alleviate the shipping crisis caused by ongoing conflicts.
  • Shipping Disruption Impact: Since the conflict erupted on February 28, shipping through the Strait has nearly ceased, leaving approximately 3,200 vessels stranded in the Gulf, affecting 20% of global oil shipments and trade for Gulf nations.
  • Transit Costs: Some shipping operators have reportedly paid up to $2 million to secure safe passage, reflecting the significant impact of the current situation on shipping costs and operational risks.
  • Humanitarian Corridor Exploration: The International Maritime Organization is considering establishing a humanitarian corridor to allow vessels facing fuel or supply shortages to safely exit the region, highlighting the importance of maritime safety amidst escalating tensions.
Wall Street analysts forecast ACHV stock price to rise
2 Analyst Rating
Wall Street analysts forecast ACHV stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
12.00
Averages
15.50
High
19.00
Current: 0.000
sliders
Low
12.00
Averages
15.50
High
19.00
Canaccord
Gary Nachman
Buy
initiated
$13
AI Analysis
2026-04-21
Reason
Canaccord
Gary Nachman
Price Target
$13
AI Analysis
2026-04-21
initiated
Buy
Reason
Canaccord analyst Gary Nachman last night initiated coverage of Achieve Life Sciences with a Buy rating and $13 price target. The company's cytisinicline is a "best-in-class" drug for nicotine dependence, where there is still a large unmet need, the analyst tells investors in a research note. Canaccord believes the regulatory path for smoking cessation is "de-risked" as cytisinicline has a better profile than Pfizer's Chantix. While a complete response letter is expected on or before the June 20 FDA action date because of third-party manufacturing, "that minor delay is already factored into the stock," contends the firm.
Canaccord
Buy
initiated
$13
2026-04-20
Reason
Canaccord
Price Target
$13
2026-04-20
initiated
Buy
Reason
Canaccord initiated coverage of Achieve Life Sciences with a Buy rating and $13 price target.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ACHV
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Valuation Metrics

The current forward P/E ratio for Achieve Life Sciences Inc (ACHV.O) is 35.34, compared to its 5-year average forward P/E of 0.91. For a more detailed relative valuation and DCF analysis to assess Achieve Life Sciences Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
0.91
Current PE
35.34
Overvalued PE
15.31
Undervalued PE
-13.49

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.23
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.30
Undervalued EV/EBITDA
-0.75

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
73.18
Current PS
13.11
Overvalued PS
288.58
Undervalued PS
-142.22

Financials

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Frequently Asked Questions

What is Achieve Life Sciences Inc (ACHV) stock price today?

The current price of ACHV is 4.8 USD — it has increased 5.26

What is Achieve Life Sciences Inc (ACHV)'s business?

Achieve Life Sciences, Inc. is a late-stage specialty pharmaceutical company. The Company focuses on addressing the global smoking health and nicotine dependence epidemic through the development and commercialization of cytisinicline. It has completed two Phase III studies with cytisinicline for smoking cessation and one Phase II study with cytisinicline in vaping cessation. Cytisinicline is a naturally occurring, plant-based alkaloid. Cytisinicline is structurally similar to nicotine and has a dual-acting mechanism of action, being both a receptor agonist and antagonist. Cytisinicline is an investigational product candidate being developed for the treatment of nicotine dependence and has not been approved by the Food and Drug Administration for any indication in the United States. Cytisinicline acts as a partial agonist/antagonist, binding to alpha-4 beta-2 nicotinic receptors in the brain and is thought to have two potential consequences in treating nicotine dependence.

What is the price predicton of ACHV Stock?

Wall Street analysts forecast ACHV stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ACHV is15.50 USD with a low forecast of 12.00 USD and a high forecast of 19.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Achieve Life Sciences Inc (ACHV)'s revenue for the last quarter?

Achieve Life Sciences Inc revenue for the last quarter amounts to -14.73M USD, increased 20.84

What is Achieve Life Sciences Inc (ACHV)'s earnings per share (EPS) for the last quarter?

Achieve Life Sciences Inc. EPS for the last quarter amounts to -17980000.00 USD, increased 95.67

How many employees does Achieve Life Sciences Inc (ACHV). have?

Achieve Life Sciences Inc (ACHV) has 28 emplpoyees as of May 07 2026.

What is Achieve Life Sciences Inc (ACHV) market cap?

Today ACHV has the market capitalization of 492.76M USD.