02096 Overview

Company Announcement: Simcere Pharma announced that its investigational new drug candidate, SIM0610, has received Clinical Trial Approval from the National Medical Products Administration of China.

Drug Purpose: SIM0610 is a Bispecific Antibody-Drug Conjugate (BsADC) intended for evaluation in patients with locally advanced or metastatic solid tumors.

Market Activity: The company's stock experienced a slight increase of 0.050 (+0.389%) with short selling amounting to $5.28 million and a ratio of 10.987%.

Stock Information: Note that the Hong Kong stock quote is delayed by at least 15 minutes, and the short selling data is as of December 23, 2025, at 16:25.

Licensing Agreement: SIMCERE PHARMA's subsidiary, Jiangsu Zaiming, has signed an exclusive licensing agreement with Ipsen Pharma SAS for the global rights to develop, manufacture, and commercialize the antibody-drug conjugate SIM0613 outside of Greater China.

Financial Terms: The agreement includes potential earnings of up to US$1.06 billion for SIMCERE PHARMA, consisting of a US$45 million upfront payment and additional milestone payments, along with tiered royalties on sales contingent on successful development and regulatory approvals.

Stock Performance: SIMCERE PHARMA (02096.HK) experienced a slight decline of 0.445% with a short selling amount of $9.32 million and a ratio of 11.904%.

New Drug Inclusion: ENZESHU (Suvemcitug for injection) has been officially added to the National Basic Medical Insurance Drugs Catalogue, effective January 1, 2026.

Renewal of Drug Listing: ENDOSTAR (Recombinant Human Endostatin for Injection) has successfully completed its renewal under the National Reimbursement Drug List (NRDL).

Market Information: The stock quote for HK stocks is delayed by at least 15 minutes, with short selling data as of December 5, 2025.

Stock Performance: Various stocks are listed with their current prices, short selling data, and investment ratings, indicating a mix of gains and losses across different companies.

Investment Ratings: Most stocks mentioned, including FORTUNE REIT, OMNIVISION, and Alibaba, are rated as "Buy," suggesting a positive outlook from analysts.

Stock Performance Overview: Several pharmaceutical stocks showed mixed performance, with HENGRUI PHARMA and HANSOH PHARMA experiencing gains, while CSPC PHARMA and KELUN PHARM saw slight declines.

Short Selling Data: Short selling activity was notable, particularly for CSPC PHARMA and SIMCERE PHARMA, with significant ratios indicating investor caution in these stocks.

Tariff Announcement: US President Donald Trump will impose a 100% tariff on imported branded or patented finished drugs starting in October, unless manufacturers establish production facilities in the US; generic drugs and certain intermediates will be exempt.

Impact on Chinese Drug Companies: The tariff's effect on China's innovative drug sector is expected to be minimal, as few companies export directly to the US, with many having production capabilities in the US or using local contract manufacturers.