What’s Behind the 165% Surge in Minerva Neurosciences Stock (NERV) Today?
Stock Surge: Minerva Neurosciences (NERV) stock soared 163.16% in pre-market trading after announcing a $200 million securities purchase agreement with institutional investors, including $80 million in upfront funding.
Funding Purpose: The company plans to use the proceeds to advance its research and development of roluperidone, a treatment for schizophrenia, including a confirmatory Phase 3 trial and preparation for a New Drug Application resubmission.
CEO Statement: Dr. Remy Luthringer emphasized the company's commitment to successfully executing the trial to demonstrate the effectiveness of roluperidone in treating negative symptoms of schizophrenia.
Analyst Coverage: Despite the stock's rise, analyst coverage is limited, with TipRanks’ AI analyst rating NERV stock as Underperform due to concerns over financial instability and lack of revenue.
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Minerva Neurosciences to Host KOL Event on Schizophrenia Treatment
- KOL Event Announcement: Minerva Neurosciences will host a virtual KOL event on February 3, 2026, featuring experts in psychology and psychiatry to discuss the patient burden of negative symptoms of schizophrenia and assessment challenges, which is expected to provide critical insights for the upcoming Phase 3 trial.
- Clinical Trial Plans: The company plans to initiate a confirmatory Phase 3 trial in 2026 using a novel protocol aligned with FDA considerations, aimed at maximizing the probability of a successful outcome and addressing the unmet medical need for treating negative symptoms.
- Impact of Negative Symptoms: Approximately 50% to 60% of individuals with schizophrenia experience at least one primary negative symptom, highlighting the urgent medical need as current antipsychotics primarily address positive symptoms without efficacy against negative symptoms.
- Expert Backgrounds: The event will feature Gregory Strauss, PhD, and Brian Kirkpatrick, MD, both of whom have extensive experience in schizophrenia research and have received over $82 million in research funding, underscoring their authority in the field and potential influence on future treatment options.

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