Viking Therapeutics: A Potential New Star in Weight Loss Drugs
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 37 minutes ago
0mins
Source: Fool
- Market Share Shift: Eli Lilly currently holds a 60% share of the U.S. GLP-1 weight loss drug market, and while Novo Nordisk remains a giant, Lilly's success indicates increasing competitive pressure from new entrants.
- Clinical Trial Progress: Viking Therapeutics' VK2735 is undergoing phase 3 trials, with the oral version set to enter phase 3 in Q4, potentially providing the company with an opportunity to compete against Lilly.
- Weight Loss Market Outlook: Analysts forecast the weight loss drug market to approach $100 billion by 2030, and Viking's dual GLP-1/GIP offering stands out, potentially attracting more attention from patients and doctors.
- Competitive Challenges: Although Viking's clinical results are comparable to those of Lilly and Novo, achieving market success will require overcoming challenges such as Lilly's brand trust and manufacturing capabilities.
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Analyst Views on VKTX
Wall Street analysts forecast VKTX stock price to rise
12 Analyst Rating
12 Buy
0 Hold
0 Sell
Strong Buy
Current: 29.440
Low
70.00
Averages
97.00
High
125.00
Current: 29.440
Low
70.00
Averages
97.00
High
125.00
About VKTX
Viking Therapeutics, Inc. is a clinical-stage biopharmaceutical company that is focused on the development of therapies for the treatment of metabolic and endocrine disorders. Its clinical programs include VK2735, a novel dual agonist of the glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide receptors for the potential treatment of various metabolic disorders. It is evaluating an oral formulation of VK2735 in a Phase II trial. It is also developing VK2809, a novel, orally available, small molecule selective thyroid hormone receptor beta agonist for the treatment of lipid and metabolic disorders. Its newest program is evaluating a series of internally developed dual amylin and calcitonin receptor agonists for the treatment of obesity and other metabolic disorders. In the rare disease space, it is developing VK0214, a novel, orally available, small molecule selective thyroid hormone receptor beta agonist for the potential treatment of X-linked adrenoleukodystrophy.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Conference Participation: Viking Therapeutics will participate in the William Blair 46th Annual Growth Stock Conference and the Jefferies Global Healthcare Conference in June, showcasing its latest advancements in treating metabolic and endocrine disorders, which is expected to enhance the company's visibility among investors.
- Clinical Trial Progress: The company is conducting Phase 3 clinical trials for VK2735 in obesity, including VANQUISH-1 and VANQUISH-2, with preliminary data indicating a favorable safety and tolerability profile, potentially offering new treatment options for patients with metabolic disorders.
- New Drug Development Success: VK2809 successfully met both primary and secondary endpoints in a Phase 2b study for biopsy-confirmed non-alcoholic steatohepatitis (NASH) and fibrosis, demonstrating its potential in improving lipid and metabolic disorders.
- Rare Disease Treatment: Viking is developing VK0214 for the treatment of X-linked adrenoleukodystrophy (X-ALD), which showed good safety in a Phase 1b trial while significantly reducing plasma levels of very long-chain fatty acids, potentially providing new hope for patients.
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- Market Share Shift: Eli Lilly currently holds a 60% share of the U.S. GLP-1 weight loss drug market, and while Novo Nordisk remains a giant, Lilly's success indicates increasing competitive pressure from new entrants.
- Clinical Trial Progress: Viking Therapeutics' VK2735 is undergoing phase 3 trials, with the oral version set to enter phase 3 in Q4, potentially providing the company with an opportunity to compete against Lilly.
- Weight Loss Market Outlook: Analysts forecast the weight loss drug market to approach $100 billion by 2030, and Viking's dual GLP-1/GIP offering stands out, potentially attracting more attention from patients and doctors.
- Competitive Challenges: Although Viking's clinical results are comparable to those of Lilly and Novo, achieving market success will require overcoming challenges such as Lilly's brand trust and manufacturing capabilities.
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- Market Share Leadership: Eli Lilly commands a 60% share of the U.S. GLP-1 weight loss drug market, showcasing its competitive strength despite Novo Nordisk's long-standing presence since 2017.
- Significant Revenue Growth: Eli Lilly's tirzepatide, marketed as Mounjaro and Zepbound, generated over $12 billion in revenue in the latest quarter, indicating robust demand and profitability for its weight loss products.
- Viking's Potential: Viking Therapeutics is conducting phase 3 trials for VK2735, which demonstrated over 14% weight reduction in phase 2 trials, positioning it as a potential competitor to market leader Eli Lilly if approved.
- Expansive Market Outlook: Analysts forecast the weight loss drug market to reach nearly $100 billion by 2030, with Viking's unique dual GLP-1/GIP formulation potentially attracting significant interest from patients and doctors alike.
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- Conference Participation: Viking Therapeutics will present at the William Blair 46th Annual Growth Stock Conference from June 2-4, showcasing its advancements in metabolic and endocrine disorders to investors.
- Investor Engagement: At the Jefferies Global Healthcare Conference, Viking's management will engage in a fireside chat and investor meetings, enhancing communication with investors and increasing the company's visibility in the capital markets.
- Clinical Trial Progress: Viking is conducting Phase 3 trials for VK2735 in obesity, with preliminary data indicating a favorable safety and tolerability profile, potentially laying the groundwork for future market performance.
- New Drug Development Updates: VK2809 has shown significant efficacy in treating non-alcoholic fatty liver disease (NAFLD) and elevated LDL-C in Phase 2 trials, further solidifying Viking's innovative position in the metabolic disease treatment landscape.
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- Market Leadership Shift: While Novo Nordisk was the first to launch GLP-1 weight-loss drugs, production issues have led to phenomenal sales growth of 125% for Eli Lilly's Mounjaro and 80% for Zepbound in Q1 2026, highlighting intense market competition.
- Drug Efficacy Comparison: Novo Nordisk's Wagovy pill has shown strong uptake, attracting new customers despite facing pricing pressures and patent expirations, with a P/E ratio of 10x indicating long-term growth potential.
- High-Risk Investment Opportunity: Viking Therapeutics, a money-losing startup with GLP-1 drugs in clinical trials, has seen dramatic price swings but negligible growth over the past year, suggesting that a breakthrough could lead to significant share price increases, appealing to aggressive investors.
- Investment Strategy Recommendations: For those seeking a balance of risk and reward, Novo Nordisk may be the best choice, while Eli Lilly leverages its leadership position to diversify its drug pipeline, and Viking presents a high-risk potential wildcard.
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- Industry Leader: Eli Lilly's GLP-1 drugs Mounjaro and Zepbound saw sales increase by 125% and 80% respectively in Q1 2026, demonstrating strong performance in the weight-loss drug market, although its high P/E ratio of 35x raises concerns, yet investors remain optimistic about future growth.
- Novo Nordisk's Comeback: The launch of Novo Nordisk's Wagovy pill has been well-received, attracting many new customers despite facing pricing pressures and patent expirations; its appealing P/E ratio of 10x may present a turnaround opportunity for value-focused investors.
- Risky Investment Choice: Viking Therapeutics, a startup with GLP-1 drugs in clinical trials, has experienced significant stock price volatility without substantial growth, but a breakthrough could lead to a material price increase, making it suitable for aggressive growth investors.
- Market Diversification: In the GLP-1 drug sector, Eli Lilly and Novo Nordisk each have their strengths, with the former expanding its drug pipeline while the latter may attract more investor interest due to its pricing advantages and market potential.
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