Twist Bioscience Executive's Stock Sale Raises Eyebrows
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 3 days ago
0mins
Source: Fool
- Executive Trading Overview: Chief Legal Officer Dennis Cho sold 14,205 shares of Twist Bioscience on May 29, 2026, for approximately $991,000, marking his largest single sale in two years, nearly 12 times the average size of his 54 previous sell transactions.
- Holding Proportion Change: This sale represented 10.58% of Cho's direct holdings, reducing his shares from 134,299 to 120,094, indicating a strategic reduction while still reflecting confidence in the company's future prospects.
- Company Performance Context: As of May 29, 2026, Twist Bioscience's stock appreciated 131.5% over the past year, hitting a 52-week high of $80.50 on June 4, showcasing the company's strong performance and growing market demand in the biotechnology sector.
- Investor Confidence: Cho's stock sale was executed under a prearranged Rule 10b5-1 trading plan established in May 2025 to avoid insider trading allegations, and with 120,094 shares remaining, it suggests he is not in a hurry to liquidate his holdings, alleviating investor concerns.
Trade with 70% Backtested Accuracy
Stop guessing "Should I Buy TWST?" and start using high-conviction signals backed by rigorous historical data.
Sign up today to access powerful investing tools and make smarter, data-driven decisions.
Analyst Views on TWST
Wall Street analysts forecast TWST stock price to fall
5 Analyst Rating
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 70.040
Low
39.00
Averages
41.25
High
43.00
Current: 70.040
Low
39.00
Averages
41.25
High
43.00
About TWST
Twist Bioscience Corporation provides customizable solutions across the biological continuum that enable scientific discovery and development across therapeutics, diagnostics, and other high-growth markets. The Company's proprietary silicon-based platform delivers precision, scale, and speed, supporting consistent, high-quality performance across a range of applications. The Company’s platform is a differentiated method of manufacturing synthetic deoxyribonucleic acid (DNA) by writing DNA on a silicon chip. By integrating proprietary hardware, software, and scalable infrastructure, including its e-commerce platform. The Company has extended this platform beyond DNA synthesis to offer an integrated portfolio that includes synthetic genes, next-generation sequencing, applications, sample preparation tools, antibody libraries, and biologic discovery services. Leveraging the same platform, it also manufactures synthetic ribonucleic acid (RNA) and expresses antibody proteins.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Twist Bioscience Executive's Stock Sale Raises Eyebrows
- Executive Trading Overview: Chief Legal Officer Dennis Cho sold 14,205 shares of Twist Bioscience on May 29, 2026, for approximately $991,000, marking his largest single sale in two years, nearly 12 times the average size of his 54 previous sell transactions.
- Holding Proportion Change: This sale represented 10.58% of Cho's direct holdings, reducing his shares from 134,299 to 120,094, indicating a strategic reduction while still reflecting confidence in the company's future prospects.
- Company Performance Context: As of May 29, 2026, Twist Bioscience's stock appreciated 131.5% over the past year, hitting a 52-week high of $80.50 on June 4, showcasing the company's strong performance and growing market demand in the biotechnology sector.
- Investor Confidence: Cho's stock sale was executed under a prearranged Rule 10b5-1 trading plan established in May 2025 to avoid insider trading allegations, and with 120,094 shares remaining, it suggests he is not in a hurry to liquidate his holdings, alleviating investor concerns.
See More
Dennis Cho Sells Twist Bioscience Shares Amid Stock Surge
- Sale Details: Chief Legal Officer Dennis Cho sold 14,205 shares of Twist Bioscience on May 29, 2026, for approximately $991,000 at a price of $69.75 per share, reducing his direct holdings from 134,299 to 120,094 shares, marking the largest single sale among his 54 recent transactions.
- Transaction Context: This sale was executed under a prearranged Rule 10b5-1 trading plan adopted in May 2025, indicating that Cho is not in a hurry to liquidate his holdings, as he still retains 120,094 shares.
- Company Performance: Twist Bioscience reported a robust 19% year-over-year revenue growth to $110.7 million for its fiscal second quarter ending March 31, prompting the company to raise its full-year sales growth guidance for 2026 to between 17% and 19%.
- Market Reaction and Outlook: The sale occurred during a period of soaring stock prices, with shares reaching a 52-week high of $80.50 on June 4, reflecting strong business performance and investor confidence in the biotechnology sector.
See More
Twist Bioscience Executive Sells Over 14,000 Shares
- Transaction Scale Analysis: Chief Legal Officer Dennis Cho sold 14,205 shares of Twist Bioscience on May 29, 2026, for approximately $991,000, marking the largest single sale in the past two years, nearly 12 times his average sell-only trade size across 54 events.
- Holding Proportion Change: This sale represented 10.58% of Cho's direct holdings, reducing his shares from 134,299 to 120,094, indicating a significant step-down compared to the smaller incremental sales that characterized his trading since January 2025.
- Market Performance Context: As of the transaction date, Twist Bioscience shares appreciated 131.5% over the past year, with Cho's remaining direct holdings representing about 0.19% of outstanding shares, suggesting confidence in the company's future stock performance.
- Investor Confidence: Cho's stock sale was executed under a prearranged trading plan established in May 2025 to avoid insider trading accusations, and his remaining 120,094 shares indicate he is not in a rush to divest, alleviating investor concerns.
See More
Twist Bioscience CEO Sells Shares for $1.12 Million Profit
- Insider Stock Transaction: Twist Bioscience CEO Emily Leproust exercised 16,470 options and sold the shares for approximately $1.12 million, indicating ongoing executive confidence in the company's stock performance.
- Shareholding Analysis: Post-transaction, Leproust holds 846,872 shares directly and has 538,218 employee stock options outstanding, reflecting significant ongoing financial exposure to future equity value.
- Strong Performance: As of May 31, 2026, Twist Bioscience shares delivered a total return of 128.23% over the past year, showcasing robust growth momentum in the synthetic biology sector.
- Revenue Outlook Upgrade: The company expects total revenue for fiscal 2026 to increase by 17% to 19%, reaching between $442 million and $447 million, highlighting strong demand for its DNA synthesis services and competitive market position.
See More
Analysis of Twist Bioscience CEO's Stock Sale Transaction
- Stock Sale Overview: On May 28, 2026, Twist Bioscience CEO Emily Leproust exercised options to sell 16,470 shares of common stock for approximately $1.12 million, with the transaction value based on a weighted average purchase price of $67.91 from SEC Form 4, indicating high liquidity and market confidence.
- Ownership Change: This transaction reduced Leproust's direct holdings to 846,872 shares, representing a 1.91% decrease in her direct ownership, suggesting active trading by executives that may influence investor perceptions of corporate governance.
- Financial Performance Boost: Twist Bioscience reported a 28% year-over-year increase in sales from its DNA synthesis and protein solutions lab in Q2 of fiscal 2026, alongside a rise in gross margin to 51.6%, highlighting the company's strong growth potential in the synthetic biology sector.
- Optimistic Future Outlook: Management has raised the fiscal 2026 revenue outlook to between $442 million and $447 million, reflecting a growth rate of 17% to 19%, and expects to report positive adjusted EBITDA in Q4, indicating enhanced competitiveness and profitability in the market.
See More
Twist Bioscience Launches Complex Genes Product Line
- Product Line Expansion: On May 4, Twist Bioscience launched an early access version of 'Complex Genes,' which supports DNA sequences up to 7,000 base pairs, significantly enhancing gene length and structural complexity while meeting 99.5% of clonal gene orders and 99.9% of all DNA product demands, thereby strengthening the company's competitive position in the gene synthesis market.
- Market Demand Response: CEO Emily Leproust emphasized that researchers require partners capable of rapidly delivering complex genes at scale, and this expansion allows the company to accept a broader range of designs, thus shortening discovery timelines and further driving innovation in the biotech sector.
- Technical Support: The new capability supports AI-driven drug discovery and nucleic acid therapeutics, where precise synthesis of complex sequences is critical, indicating Twist Bioscience's strategic positioning in cutting-edge biotechnology.
- Global Operations: Twist Bioscience operates across the Americas, EMEA, and APAC, developing patented semiconductor-based synthetic DNA production techniques, showcasing its potential for global market expansion and technological innovation.
See More
Twist Bioscience Executive's Stock Sale Raises Eyebrows
- Executive Trading Overview: Chief Legal Officer Dennis Cho sold 14,205 shares of Twist Bioscience on May 29, 2026, for approximately $991,000, marking his largest single sale in two years, nearly 12 times the average size of his 54 previous sell transactions.
- Holding Proportion Change: This sale represented 10.58% of Cho's direct holdings, reducing his shares from 134,299 to 120,094, indicating a strategic reduction while still reflecting confidence in the company's future prospects.
- Company Performance Context: As of May 29, 2026, Twist Bioscience's stock appreciated 131.5% over the past year, hitting a 52-week high of $80.50 on June 4, showcasing the company's strong performance and growing market demand in the biotechnology sector.
- Investor Confidence: Cho's stock sale was executed under a prearranged Rule 10b5-1 trading plan established in May 2025 to avoid insider trading allegations, and with 120,094 shares remaining, it suggests he is not in a hurry to liquidate his holdings, alleviating investor concerns.
See More
Dennis Cho Sells Twist Bioscience Shares Amid Stock Surge
- Sale Details: Chief Legal Officer Dennis Cho sold 14,205 shares of Twist Bioscience on May 29, 2026, for approximately $991,000 at a price of $69.75 per share, reducing his direct holdings from 134,299 to 120,094 shares, marking the largest single sale among his 54 recent transactions.
- Transaction Context: This sale was executed under a prearranged Rule 10b5-1 trading plan adopted in May 2025, indicating that Cho is not in a hurry to liquidate his holdings, as he still retains 120,094 shares.
- Company Performance: Twist Bioscience reported a robust 19% year-over-year revenue growth to $110.7 million for its fiscal second quarter ending March 31, prompting the company to raise its full-year sales growth guidance for 2026 to between 17% and 19%.
- Market Reaction and Outlook: The sale occurred during a period of soaring stock prices, with shares reaching a 52-week high of $80.50 on June 4, reflecting strong business performance and investor confidence in the biotechnology sector.
See More
Twist Bioscience Executive Sells Over 14,000 Shares
- Transaction Scale Analysis: Chief Legal Officer Dennis Cho sold 14,205 shares of Twist Bioscience on May 29, 2026, for approximately $991,000, marking the largest single sale in the past two years, nearly 12 times his average sell-only trade size across 54 events.
- Holding Proportion Change: This sale represented 10.58% of Cho's direct holdings, reducing his shares from 134,299 to 120,094, indicating a significant step-down compared to the smaller incremental sales that characterized his trading since January 2025.
- Market Performance Context: As of the transaction date, Twist Bioscience shares appreciated 131.5% over the past year, with Cho's remaining direct holdings representing about 0.19% of outstanding shares, suggesting confidence in the company's future stock performance.
- Investor Confidence: Cho's stock sale was executed under a prearranged trading plan established in May 2025 to avoid insider trading accusations, and his remaining 120,094 shares indicate he is not in a rush to divest, alleviating investor concerns.
See More
Twist Bioscience CEO Sells Shares for $1.12 Million Profit
- Insider Stock Transaction: Twist Bioscience CEO Emily Leproust exercised 16,470 options and sold the shares for approximately $1.12 million, indicating ongoing executive confidence in the company's stock performance.
- Shareholding Analysis: Post-transaction, Leproust holds 846,872 shares directly and has 538,218 employee stock options outstanding, reflecting significant ongoing financial exposure to future equity value.
- Strong Performance: As of May 31, 2026, Twist Bioscience shares delivered a total return of 128.23% over the past year, showcasing robust growth momentum in the synthetic biology sector.
- Revenue Outlook Upgrade: The company expects total revenue for fiscal 2026 to increase by 17% to 19%, reaching between $442 million and $447 million, highlighting strong demand for its DNA synthesis services and competitive market position.
See More
Analysis of Twist Bioscience CEO's Stock Sale Transaction
- Stock Sale Overview: On May 28, 2026, Twist Bioscience CEO Emily Leproust exercised options to sell 16,470 shares of common stock for approximately $1.12 million, with the transaction value based on a weighted average purchase price of $67.91 from SEC Form 4, indicating high liquidity and market confidence.
- Ownership Change: This transaction reduced Leproust's direct holdings to 846,872 shares, representing a 1.91% decrease in her direct ownership, suggesting active trading by executives that may influence investor perceptions of corporate governance.
- Financial Performance Boost: Twist Bioscience reported a 28% year-over-year increase in sales from its DNA synthesis and protein solutions lab in Q2 of fiscal 2026, alongside a rise in gross margin to 51.6%, highlighting the company's strong growth potential in the synthetic biology sector.
- Optimistic Future Outlook: Management has raised the fiscal 2026 revenue outlook to between $442 million and $447 million, reflecting a growth rate of 17% to 19%, and expects to report positive adjusted EBITDA in Q4, indicating enhanced competitiveness and profitability in the market.
See More
Twist Bioscience Launches Complex Genes Product Line
- Product Line Expansion: On May 4, Twist Bioscience launched an early access version of 'Complex Genes,' which supports DNA sequences up to 7,000 base pairs, significantly enhancing gene length and structural complexity while meeting 99.5% of clonal gene orders and 99.9% of all DNA product demands, thereby strengthening the company's competitive position in the gene synthesis market.
- Market Demand Response: CEO Emily Leproust emphasized that researchers require partners capable of rapidly delivering complex genes at scale, and this expansion allows the company to accept a broader range of designs, thus shortening discovery timelines and further driving innovation in the biotech sector.
- Technical Support: The new capability supports AI-driven drug discovery and nucleic acid therapeutics, where precise synthesis of complex sequences is critical, indicating Twist Bioscience's strategic positioning in cutting-edge biotechnology.
- Global Operations: Twist Bioscience operates across the Americas, EMEA, and APAC, developing patented semiconductor-based synthetic DNA production techniques, showcasing its potential for global market expansion and technological innovation.
See More
