Tivic Health Presents Entolimod Data at TechWatch Meeting
Tivic Health delivered an invited presentation at a TechWatch meeting with the Biomedical Advanced Research and Development Authority on January 26, with select members of the Department of Defense, Defense Threat Reduction Agency, National Institutes of Health (NIH) and National Institute of Allergy and Infectious Diseases. The company presented key clinical and manufacturing readiness data for Tivic's Toll-like Receptor 5 agonist, Entolimod, underscoring its potential use as a radiation countermeasure, as well as progress on manufacturing readiness that has been accelerated by newly formed subsidiary Velocity Bioworks.TechWatch meetings enable BARDA and other U.S. agencies to evaluate technology and manufacturing readiness and to identify potential pathways for funding and purchasing new technologies. Monday's meeting initiated Tivic's discussions with the agency regarding the potential for incorporating Entolimod into the Strategic National Stockpile, with key stakeholders requesting expedited follow-up. "We appreciate the U.S. government's interest in the differentiated properties of Entolimod compared to the other drugs already stockpiled for treating ARS," said Tivic CEO Jennifer Ernst. "We are fully committed to supporting BARDA and other agencies in their exploration of Entolimod through our upcoming engagements."
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New Patent Applications: Tivic Health Systems has filed two patent applications, one for TLR5 agonists like Entolimod and Entolasta to enhance cancer therapy outcomes, and another for optimized specifications of a non-invasive vagus nerve stimulation device.
Potential Benefits for Cancer Patients: The TLR5 agonists may serve as adjunctive therapies to improve the effectiveness of immuno-oncology treatments for late-stage cancer patients who are often immunocompromised.
Focus on Intellectual Property and Partnerships: CEO Jennifer Ernst emphasized the importance of expanding their intellectual property rights to create new partnership opportunities and market potential for their product candidates.
Overview of Tivic's Therapeutics: Tivic Health utilizes both biopharmaceutical and bioelectronic systems to address unmet medical needs, with a focus on enhancing immune responses and developing non-invasive medical devices for various diseases.

Earnings Announcement: Tivic Health Systems, Inc. will report its third quarter results for 2025 on November 14, 2025, via a pre-recorded conference call and webcast.
Company Overview: Tivic Health focuses on immunotherapeutics, utilizing both biopharmaceutical and bioelectronic systems to address unmet medical needs, particularly through its lead drug candidate, Entolimod™.
Innovative Approaches: The company is developing a non-invasive medical device aimed at regulating neural pathways related to various diseases, with early trials indicating promising results.
Forward-Looking Statements: The press release includes forward-looking statements that carry risks and uncertainties, advising caution in reliance on these projections.

Tivic Health Participation: Tivic Health's CEO, Jennifer Ernst, will participate in the Constellation Forum on October 23, discussing advancements in bioelectronic medicine alongside other industry leaders.
Panel Discussion Focus: The panel titled "Building a Big Tent" will address the need for collaboration across the healthcare ecosystem to enhance the adoption and impact of bioelectronic medicine.
About Bioelectronic Medicine: The 2025 program will spotlight bioelectronic medicine, which integrates device technology with patient care, aiming to overcome challenges and explore commercialization strategies.
Tivic Health's Innovations: Tivic Health is developing a dual platform that combines biopharmaceutical and bioelectronic systems to address unmet medical needs, including a lead drug candidate for acute radiation syndrome and a promising non-invasive medical device targeting neural pathways.

Emerging Growth Conference Announcement: The 86th Emerging Growth Conference is scheduled for September 24 & 25, 2025, focusing on companies with strong management and growth potential across various sectors.
Keynote Speakers and Schedule: The conference features multiple keynote speakers from various companies, including Kneat.com, Zapp Electric Vehicles, and Citizens, Inc., with sessions conducted via video webcasts.

Tivic Health Presentation: Tivic Health's CEO, Jennifer Ernst, will present at the Emerging Growth virtual conference on September 25, 2025, discussing the company's strategic shift into the biopharmaceutical sector and its lead drug candidate, Entolimod, for treating Acute Radiation Syndrome.
Entolimod and Neutropenia: The presentation will highlight Tivic's licensing of Statera Biopharma's TLR5 agonist portfolio, including Entolimod, and its potential to address Neutropenia, a significant unmet medical need affecting various demographics.






