Tivic Expands VNS Intellectual Property Portfolio
New Patent Announcement: Tivic Health Systems, Inc. has filed a new patent application for its non-invasive vagus nerve stimulation (VNS) technology, aimed at enhancing treatment efficacy through personalized stimulation parameters and electrode positioning.
Company Vision and Products: The company emphasizes the importance of protecting its intellectual property as it develops bioelectronic VNS devices and biologic immunotherapies to address health issues related to immune system dysregulation, with existing products like ClearUP™ already on the market.
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- Significant Revenue Growth: Davis Commodities Ltd reported a revenue of $95 million for the first half ending June 30, marking a 42.1% increase from $66.9 million a year earlier, indicating strong performance in the agricultural commodity trading sector and boosting market confidence.
- Stock Price Surge: Following the earnings report, Davis Commodities' shares jumped 5.6% to $0.25 in pre-market trading, reflecting investor optimism regarding the company's future growth potential.
- Positive Market Reaction: The stock price increase post-earnings release indicates market recognition of Davis Commodities' performance, which may attract more investor interest and further drive the stock price upward.
- Optimistic Industry Outlook: With the ongoing demand for agricultural commodities, the strong earnings report not only enhances Davis Commodities' market position but also potentially provides funding for future expansion and investments.
New Patent Applications: Tivic Health Systems has filed two patent applications, one for TLR5 agonists like Entolimod and Entolasta to enhance cancer therapy outcomes, and another for optimized specifications of a non-invasive vagus nerve stimulation device.
Potential Benefits for Cancer Patients: The TLR5 agonists may serve as adjunctive therapies to improve the effectiveness of immuno-oncology treatments for late-stage cancer patients who are often immunocompromised.
Focus on Intellectual Property and Partnerships: CEO Jennifer Ernst emphasized the importance of expanding their intellectual property rights to create new partnership opportunities and market potential for their product candidates.
Overview of Tivic's Therapeutics: Tivic Health utilizes both biopharmaceutical and bioelectronic systems to address unmet medical needs, with a focus on enhancing immune responses and developing non-invasive medical devices for various diseases.

Earnings Announcement: Tivic Health Systems, Inc. will report its third quarter results for 2025 on November 14, 2025, via a pre-recorded conference call and webcast.
Company Overview: Tivic Health focuses on immunotherapeutics, utilizing both biopharmaceutical and bioelectronic systems to address unmet medical needs, particularly through its lead drug candidate, Entolimod™.
Innovative Approaches: The company is developing a non-invasive medical device aimed at regulating neural pathways related to various diseases, with early trials indicating promising results.
Forward-Looking Statements: The press release includes forward-looking statements that carry risks and uncertainties, advising caution in reliance on these projections.

Tivic Health Participation: Tivic Health's CEO, Jennifer Ernst, will participate in the Constellation Forum on October 23, discussing advancements in bioelectronic medicine alongside other industry leaders.
Panel Discussion Focus: The panel titled "Building a Big Tent" will address the need for collaboration across the healthcare ecosystem to enhance the adoption and impact of bioelectronic medicine.
About Bioelectronic Medicine: The 2025 program will spotlight bioelectronic medicine, which integrates device technology with patient care, aiming to overcome challenges and explore commercialization strategies.
Tivic Health's Innovations: Tivic Health is developing a dual platform that combines biopharmaceutical and bioelectronic systems to address unmet medical needs, including a lead drug candidate for acute radiation syndrome and a promising non-invasive medical device targeting neural pathways.

Emerging Growth Conference Announcement: The 86th Emerging Growth Conference is scheduled for September 24 & 25, 2025, focusing on companies with strong management and growth potential across various sectors.
Keynote Speakers and Schedule: The conference features multiple keynote speakers from various companies, including Kneat.com, Zapp Electric Vehicles, and Citizens, Inc., with sessions conducted via video webcasts.

Tivic Health Presentation: Tivic Health's CEO, Jennifer Ernst, will present at the Emerging Growth virtual conference on September 25, 2025, discussing the company's strategic shift into the biopharmaceutical sector and its lead drug candidate, Entolimod, for treating Acute Radiation Syndrome.
Entolimod and Neutropenia: The presentation will highlight Tivic's licensing of Statera Biopharma's TLR5 agonist portfolio, including Entolimod, and its potential to address Neutropenia, a significant unmet medical need affecting various demographics.






