TG Therapeutics Presents BRIUMVI Data at ACTRIMS Annual Meeting
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1h ago
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Should l Buy TGTX?
Source: Newsfilter
- Clinical Data Presentation: TG Therapeutics showcased clinical data on BRIUMVI (ublituximab-xiiy) at the ACTRIMS annual meeting in San Diego, California, particularly updates from the ENABLE study, emphasizing the company's ongoing commitment to advancing the understanding of MS and supporting the patient community.
- Study Design Overview: The company introduced the design of the ULTIMATE I and II randomized double-blind clinical trials for patients with relapsing multiple sclerosis (RMS), which enrolled a total of 1,094 patients, aimed at evaluating the efficacy and safety of BRIUMVI.
- International Participation: The ULTIMATE I and II trials were conducted across 10 countries, demonstrating TG Therapeutics' global reach and contribution to MS treatment, further solidifying its position in the biopharmaceutical industry.
- Novel Drug Advantages: BRIUMVI, as a novel monoclonal antibody targeting CD20-positive B cells, utilizes glycoengineering to achieve efficient B-cell depletion at low doses, expected to provide more effective treatment options for RMS patients and drive future market growth for the company.
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Analyst Views on TGTX
Wall Street analysts forecast TGTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for TGTX is 43.50 USD with a low forecast of 15.00 USD and a high forecast of 60.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
4 Analyst Rating
3 Buy
0 Hold
1 Sell
Moderate Buy
Current: 29.120
Low
15.00
Averages
43.50
High
60.00
Current: 29.120
Low
15.00
Averages
43.50
High
60.00
About TGTX
TG Therapeutics, Inc. is a fully integrated, commercial stage, biopharmaceutical company. The Company is focused on the acquisition, development, and commercialization of novel treatments for B-cell diseases. Its clinical drug candidates are Ublituximab IV (anti-CD20 mAb), Ublituximab Subcutaneous (anti-CD20 mAb), Azer-cel, TG-1701 (BTK inhibitor), and TG-1801 (anti-CD47/CD19 bispecific mAb). BRIUMVI is an anti-CD20 monoclonal antibody for the treatment of RMS, which includes clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. TG-1701 is a novel, orally available and covalently bound Bruton’s tyrosine kinase (BTK) inhibitor that exhibits selectivity to BTK in vitro kinase screening. TG-1801 is a bispecific CD47 and CD19 antibody. It also evaluates complementary products, technologies and companies for in-licensing, partnership, acquisition, and/or investment opportunities.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
TG Therapeutics Presents BRIUMVI Data at ACTRIMS Annual Meeting
- Clinical Data Presentation: TG Therapeutics showcased clinical data on BRIUMVI (ublituximab-xiiy) at the ACTRIMS annual meeting in San Diego, California, particularly updates from the ENABLE study, emphasizing the company's ongoing commitment to advancing the understanding of MS and supporting the patient community.
- Study Design Overview: The company introduced the design of the ULTIMATE I and II randomized double-blind clinical trials for patients with relapsing multiple sclerosis (RMS), which enrolled a total of 1,094 patients, aimed at evaluating the efficacy and safety of BRIUMVI.
- International Participation: The ULTIMATE I and II trials were conducted across 10 countries, demonstrating TG Therapeutics' global reach and contribution to MS treatment, further solidifying its position in the biopharmaceutical industry.
- Novel Drug Advantages: BRIUMVI, as a novel monoclonal antibody targeting CD20-positive B cells, utilizes glycoengineering to achieve efficient B-cell depletion at low doses, expected to provide more effective treatment options for RMS patients and drive future market growth for the company.
See More
Hussman Strategic Advisors Exits Entire Position in TG Therapeutics
- Position Change: Hussman Strategic Advisors disclosed in an SEC filing that it sold its entire position of 126,000 shares in TG Therapeutics, which previously represented 1.0% of its assets under management, indicating a cautious outlook on the company's future performance.
- Financial Performance: TG Therapeutics reported preliminary fourth-quarter revenue of $182 million for its main product as of January 30, and despite a significant 92.8% year-over-year growth to $161.7 million in the third quarter, the overall performance could not offset the 11.8% decline in its stock over the past year.
- Market Comparison: The underperformance of TG Therapeutics' stock, losing 11.8%, contrasts sharply with the Nasdaq Composite and S&P 500's gains of 20% and 15.8%, respectively, highlighting a lack of competitive edge in the biotechnology sector that may pose higher risks for investors.
- Investor Implications: The complete exit by Hussman suggests a diminishing confidence in TG Therapeutics, prompting investors to closely monitor the company's future strategic partnerships and clinical program developments to assess potential growth opportunities in oncology and immunology markets.
See More
Goldman Sachs Raises TG Therapeutics Price Target to $39, Briumvi Now Available in 16 Countries
- Price Target Increase: Goldman Sachs raised TG Therapeutics' price target from $37 to $39 while maintaining a 'neutral' rating, indicating over a 32% upside potential, reflecting market optimism regarding the company's future growth prospects.
- Briumvi Market Performance: CEO Michael Weiss stated that Briumvi is now available in 16 countries, with over 20,000 patients prescribed to date, primarily in the U.S., laying a solid foundation for future revenue growth for the company.
- Revenue Expectations: The company anticipates Briumvi's U.S. revenue to range between $825 million and $850 million, which will be a major driver of overall revenue, with a forecast of $875 million to $900 million by 2026, indicating strong market demand.
- Improved Retail Sentiment: According to Stocktwits data, retail sentiment on TG Therapeutics has improved from 'bullish' to 'extremely bullish' over the past month, with message volume surging over 500% in the last week, demonstrating strong investor interest in the stock.
See More
S&P 500 Index Falls 0.53% as Tech Stocks Weigh Down Market
- Market Weakness: The S&P 500 Index closed down 0.53% and the Nasdaq 100 Index fell 1.07%, indicating that weakness in technology stocks and chip makers negatively impacted the broader market, reflecting investor concerns over rising geopolitical risks.
- Positive Economic Data: U.S. November retail sales rose 0.6% month-over-month, exceeding expectations of 0.5%, while the November Producer Price Index increased 3.0% year-over-year, stronger than the anticipated 2.7%, suggesting a rebound in economic activity that could support the market.
- Rising Oil Prices: WTI crude oil surged to a 2.5-month high amid concerns over the situation in Iran, driving investors towards safe-haven assets, with gold and silver also reaching new highs, indicating increased demand for secure investments.
- Fed Policy Expectations: The market is pricing in a 5% chance of a 25 basis point rate cut at the upcoming FOMC meeting on January 27-28, reflecting a cautious outlook among investors regarding future monetary policy.
See More
S&P 500, Dow, and Nasdaq Decline Amid Rising Geopolitical Risks
- Market Weakness: The S&P 500 and Nasdaq 100 fell by 0.96% and 1.53%, respectively, hitting one-week lows primarily due to weakness in chipmakers and tech stocks, indicating growing concerns about the economic outlook.
- Rising Geopolitical Risks: Heightened tensions regarding the U.S. response to the situation in Iran have led to increased investor demand for safe-haven assets, pushing WTI crude oil to a 2.5-month high and driving precious metals prices up significantly.
- Strong Economic Data: U.S. November retail sales rose by 0.6% month-over-month, exceeding expectations of 0.5%, while the November Producer Price Index increased by 3.0% year-over-year, demonstrating economic resilience that may influence the Fed's interest rate decisions.
- Tech Stocks Under Pressure: The Magnificent Seven tech stocks, including Nvidia, Amazon, and Tesla, saw declines of over 2%, reflecting market concerns about high valuations in the tech sector, which could impact overall market sentiment.
See More
S&P 500, Dow, and Nasdaq Decline; Nasdaq Hits One-Week Low
- Market Decline: The S&P 500 fell by 0.75%, the Dow by 0.46%, and the Nasdaq by 1.22%, reflecting investor concerns over technology stocks and chipmakers, which may undermine overall market confidence.
- Geopolitical Risks Rise: Heightened tensions in Iran pushed WTI crude oil to a 2.5-month high, prompting investors to seek safe-haven assets like gold and silver, which reached new highs, indicating market uncertainty about future economic conditions.
- Strong Economic Data: U.S. November retail sales rose 0.6% month-over-month, exceeding expectations of 0.5%, while the Producer Price Index (PPI) increased by 3.0% year-over-year, suggesting economic resilience that could influence the Fed's monetary policy decisions.
- Weakness in Tech Stocks: Major tech stocks, including Nvidia, Amazon, and Apple, experienced declines, dragging down overall market performance, prompting investors to closely monitor the upcoming earnings season and its potential impact on the market.
See More
TG Therapeutics Presents BRIUMVI Data at ACTRIMS Annual Meeting
- Clinical Data Presentation: TG Therapeutics showcased clinical data on BRIUMVI (ublituximab-xiiy) at the ACTRIMS annual meeting in San Diego, California, particularly updates from the ENABLE study, emphasizing the company's ongoing commitment to advancing the understanding of MS and supporting the patient community.
- Study Design Overview: The company introduced the design of the ULTIMATE I and II randomized double-blind clinical trials for patients with relapsing multiple sclerosis (RMS), which enrolled a total of 1,094 patients, aimed at evaluating the efficacy and safety of BRIUMVI.
- International Participation: The ULTIMATE I and II trials were conducted across 10 countries, demonstrating TG Therapeutics' global reach and contribution to MS treatment, further solidifying its position in the biopharmaceutical industry.
- Novel Drug Advantages: BRIUMVI, as a novel monoclonal antibody targeting CD20-positive B cells, utilizes glycoengineering to achieve efficient B-cell depletion at low doses, expected to provide more effective treatment options for RMS patients and drive future market growth for the company.
See More
Hussman Strategic Advisors Exits Entire Position in TG Therapeutics
- Position Change: Hussman Strategic Advisors disclosed in an SEC filing that it sold its entire position of 126,000 shares in TG Therapeutics, which previously represented 1.0% of its assets under management, indicating a cautious outlook on the company's future performance.
- Financial Performance: TG Therapeutics reported preliminary fourth-quarter revenue of $182 million for its main product as of January 30, and despite a significant 92.8% year-over-year growth to $161.7 million in the third quarter, the overall performance could not offset the 11.8% decline in its stock over the past year.
- Market Comparison: The underperformance of TG Therapeutics' stock, losing 11.8%, contrasts sharply with the Nasdaq Composite and S&P 500's gains of 20% and 15.8%, respectively, highlighting a lack of competitive edge in the biotechnology sector that may pose higher risks for investors.
- Investor Implications: The complete exit by Hussman suggests a diminishing confidence in TG Therapeutics, prompting investors to closely monitor the company's future strategic partnerships and clinical program developments to assess potential growth opportunities in oncology and immunology markets.
See More
Goldman Sachs Raises TG Therapeutics Price Target to $39, Briumvi Now Available in 16 Countries
- Price Target Increase: Goldman Sachs raised TG Therapeutics' price target from $37 to $39 while maintaining a 'neutral' rating, indicating over a 32% upside potential, reflecting market optimism regarding the company's future growth prospects.
- Briumvi Market Performance: CEO Michael Weiss stated that Briumvi is now available in 16 countries, with over 20,000 patients prescribed to date, primarily in the U.S., laying a solid foundation for future revenue growth for the company.
- Revenue Expectations: The company anticipates Briumvi's U.S. revenue to range between $825 million and $850 million, which will be a major driver of overall revenue, with a forecast of $875 million to $900 million by 2026, indicating strong market demand.
- Improved Retail Sentiment: According to Stocktwits data, retail sentiment on TG Therapeutics has improved from 'bullish' to 'extremely bullish' over the past month, with message volume surging over 500% in the last week, demonstrating strong investor interest in the stock.
See More
S&P 500 Index Falls 0.53% as Tech Stocks Weigh Down Market
- Market Weakness: The S&P 500 Index closed down 0.53% and the Nasdaq 100 Index fell 1.07%, indicating that weakness in technology stocks and chip makers negatively impacted the broader market, reflecting investor concerns over rising geopolitical risks.
- Positive Economic Data: U.S. November retail sales rose 0.6% month-over-month, exceeding expectations of 0.5%, while the November Producer Price Index increased 3.0% year-over-year, stronger than the anticipated 2.7%, suggesting a rebound in economic activity that could support the market.
- Rising Oil Prices: WTI crude oil surged to a 2.5-month high amid concerns over the situation in Iran, driving investors towards safe-haven assets, with gold and silver also reaching new highs, indicating increased demand for secure investments.
- Fed Policy Expectations: The market is pricing in a 5% chance of a 25 basis point rate cut at the upcoming FOMC meeting on January 27-28, reflecting a cautious outlook among investors regarding future monetary policy.
See More
S&P 500, Dow, and Nasdaq Decline Amid Rising Geopolitical Risks
- Market Weakness: The S&P 500 and Nasdaq 100 fell by 0.96% and 1.53%, respectively, hitting one-week lows primarily due to weakness in chipmakers and tech stocks, indicating growing concerns about the economic outlook.
- Rising Geopolitical Risks: Heightened tensions regarding the U.S. response to the situation in Iran have led to increased investor demand for safe-haven assets, pushing WTI crude oil to a 2.5-month high and driving precious metals prices up significantly.
- Strong Economic Data: U.S. November retail sales rose by 0.6% month-over-month, exceeding expectations of 0.5%, while the November Producer Price Index increased by 3.0% year-over-year, demonstrating economic resilience that may influence the Fed's interest rate decisions.
- Tech Stocks Under Pressure: The Magnificent Seven tech stocks, including Nvidia, Amazon, and Tesla, saw declines of over 2%, reflecting market concerns about high valuations in the tech sector, which could impact overall market sentiment.
See More
S&P 500, Dow, and Nasdaq Decline; Nasdaq Hits One-Week Low
- Market Decline: The S&P 500 fell by 0.75%, the Dow by 0.46%, and the Nasdaq by 1.22%, reflecting investor concerns over technology stocks and chipmakers, which may undermine overall market confidence.
- Geopolitical Risks Rise: Heightened tensions in Iran pushed WTI crude oil to a 2.5-month high, prompting investors to seek safe-haven assets like gold and silver, which reached new highs, indicating market uncertainty about future economic conditions.
- Strong Economic Data: U.S. November retail sales rose 0.6% month-over-month, exceeding expectations of 0.5%, while the Producer Price Index (PPI) increased by 3.0% year-over-year, suggesting economic resilience that could influence the Fed's monetary policy decisions.
- Weakness in Tech Stocks: Major tech stocks, including Nvidia, Amazon, and Apple, experienced declines, dragging down overall market performance, prompting investors to closely monitor the upcoming earnings season and its potential impact on the market.
See More
