SOPHiA GENETICS Reports Strong Q1 Results with 22% Revenue Growth
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1 hour ago
0mins
Should l Buy SOPH?
Source: PRnewswire
- Significant Revenue Growth: SOPHiA GENETICS achieved a 22% year-over-year revenue growth in Q1 2026, reaching $21.688 million, reflecting strong market demand for its precision medicine capabilities, particularly as U.S. hospitals and laboratories increasingly seek AI-driven solutions.
- Record Genomic Analyses: The company completed 108,000 genomic analyses in the first quarter, setting a new record that indicates the broad application of its platform and the continued expansion of its customer base, further solidifying its market position in new applications like Liquid Biopsy and BioPharma partnerships.
- Strong Future Growth Momentum: CEO Jurgi Camblong highlighted that with the launch of new applications and expansion in the U.S. market, the business momentum remains robust, which will serve as a major catalyst for future growth and enhance the company's operational leverage.
- Transparency in Non-IFRS Reporting: The company emphasizes the use of non-IFRS measures in its financial reporting to provide investors with a clearer understanding of its operational performance, acknowledging the limitations of these metrics while still offering valuable insights into the company's future financial health.
Trade with 70% Backtested Accuracy
Stop guessing "Should I Buy SOPH?" and start using high-conviction signals backed by rigorous historical data.
Sign up today to access powerful investing tools and make smarter, data-driven decisions.
Analyst Views on SOPH
Wall Street analysts forecast SOPH stock price to rise
3 Analyst Rating
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 5.320
Low
7.00
Averages
7.00
High
7.00
Current: 5.320
Low
7.00
Averages
7.00
High
7.00
About SOPH
SOPHiA GENETICS SA is a Switzerland-based company primarily engaged in the healthcare technology industry. The Company’s key product is SOPHiA DDM, which is a cloud-native software-as-a-service (SaaS) platform. The platform analyses multimodal data, including genomics, radiomics, clinical, biological, and digital pathology data, to generate actionable insights for patients with cancer or rare diseases, bringing the power of data-driven medicine to patients across the globe. Additionally, the Company aids BioPharma partners with artificial-intelligence-powered drug discovery, development, and deployment. The Company has offices in Switzerland, France, and the United States and operates worldwide.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
SOPHiA GENETICS Reports Strong Q1 Results with 22% Revenue Growth
- Significant Revenue Growth: SOPHiA GENETICS achieved a 22% year-over-year revenue growth in Q1 2026, reaching $21.688 million, reflecting strong market demand for its precision medicine capabilities, particularly as U.S. hospitals and laboratories increasingly seek AI-driven solutions.
- Record Genomic Analyses: The company completed 108,000 genomic analyses in the first quarter, setting a new record that indicates the broad application of its platform and the continued expansion of its customer base, further solidifying its market position in new applications like Liquid Biopsy and BioPharma partnerships.
- Strong Future Growth Momentum: CEO Jurgi Camblong highlighted that with the launch of new applications and expansion in the U.S. market, the business momentum remains robust, which will serve as a major catalyst for future growth and enhance the company's operational leverage.
- Transparency in Non-IFRS Reporting: The company emphasizes the use of non-IFRS measures in its financial reporting to provide investors with a clearer understanding of its operational performance, acknowledging the limitations of these metrics while still offering valuable insights into the company's future financial health.
See More
SOPHiA GENETICS Partners with Mount Sinai to Advance Cancer Research
- Collaboration Enhances Cancer Research: SOPHiA GENETICS announced a partnership with Mount Sinai Health System to adopt the AI-driven SOPHiA DDM™ platform, aimed at advancing cancer research and genomic testing capabilities, supporting care for over 4,000 oncology patients annually.
- Efficiency Optimization through Technology Integration: Mount Sinai's Molecular Pathology team will leverage SOPHiA DDM™ to enhance next-generation sequencing capabilities for blood cancers and solid tumors, significantly reducing manual interpretation time by consolidating critical steps in the analysis pipeline, thereby improving operational efficiency.
- Global Network Expansion: Mount Sinai joins a network of over 990 global institutions utilizing SOPHiA DDM™ to accelerate precision medicine, reflecting SOPHiA GENETICS' mission to democratize data-driven medicine and improve patient outcomes worldwide.
- Commitment to Scientific Innovation: The Director of Molecular Oncology Pathology at Mount Sinai stated that this collaboration reinforces the hospital's commitment to scientific innovation by integrating powerful digital tools into workflows, supporting high-quality, data-driven cancer care, and enhancing testing turnaround times to improve patient care quality.
See More
SOPHiA GENETICS (SOPH) Q4 2025 Earnings Transcript
See More
SOPHiA Genetics Q4 Earnings Report Analysis
- Earnings Performance: SOPHiA Genetics reported a Q4 GAAP EPS of -$0.28, missing the expected -$0.26, indicating ongoing challenges in profitability that may affect investor confidence.
- Revenue Growth: The company achieved Q4 revenue of $21.7 million, a 22.4% year-over-year increase, surpassing market expectations of $21.6 million, suggesting strong market demand in genomics that could lay the groundwork for future growth.
- Market Reaction: Despite the revenue beat, the EPS miss may pressure the stock price in the short term, prompting investors to monitor the company's future profitability improvement strategies to assess its long-term investment value.
- Strategic Outlook: SOPHiA Genetics needs to demonstrate stronger profitability and sustained revenue growth in upcoming reports to bolster market confidence and attract more investors, particularly in the highly competitive genomics market.
See More
SOPHiA GENETICS Reports Strong Q4 and FY 2025 Results
- Significant Revenue Growth: In Q4 2025, SOPHiA GENETICS reported a 22% year-over-year revenue increase, with a full-year growth of 19%, indicating robust momentum in the precision medicine sector that is expected to enhance shareholder value further.
- Margin Improvement: The adjusted gross margin for 2025 expanded by 140 basis points to 74.2%, even as total terabytes processed by the platform increased by 40%, demonstrating significant progress in cost control and operational efficiency.
- Customer Base Expansion: The company signed 124 new customers in 2025 and partnered with two major integrated health systems in the U.S., expected to add 60,000 analyses annually, laying a solid foundation for future revenue growth.
- Positive Future Outlook: SOPHiA GENETICS anticipates continued execution of growth strategies in the U.S. market in 2026, expansion of its Liquid Biopsy application MSK-ACCESS®, and renewed momentum in its BioPharma business, showcasing strong market potential and sustainable growth capabilities.
See More
SOPHiA GENETICS Expands U.S. Healthcare Network with Major Partnerships
- Partnership Expansion: SOPHiA GENETICS has partnered with two major U.S. healthcare systems to provide genomic testing for up to 60,000 patients annually, significantly enhancing diagnostic speed and personalized care for hereditary cancers and rare diseases.
- Technology Application Upgrade: The collaboration will leverage the SOPHiA DDM™ platform for comprehensive exome analysis of over 20,000 genes, optimizing laboratory workflows to accelerate testing turnaround times and reduce operational costs, thereby fostering internal research and innovation.
- Market Demand Response: This partnership highlights the growing need for AI-driven genomic solutions, as SOPHiA GENETICS integrates advanced bioinformatics and the collective knowledge of a global community to help healthcare institutions unlock deeper clinical insights.
- Future Development Potential: The collaboration provides both organizations with a scalable foundation to support future expansion of AI-driven precision medicine, expected to serve nearly one million cancer and rare disorder patients, further solidifying SOPHiA GENETICS' influence in the U.S. market.
See More
SOPHiA GENETICS Reports Strong Q1 Results with 22% Revenue Growth
- Significant Revenue Growth: SOPHiA GENETICS achieved a 22% year-over-year revenue growth in Q1 2026, reaching $21.688 million, reflecting strong market demand for its precision medicine capabilities, particularly as U.S. hospitals and laboratories increasingly seek AI-driven solutions.
- Record Genomic Analyses: The company completed 108,000 genomic analyses in the first quarter, setting a new record that indicates the broad application of its platform and the continued expansion of its customer base, further solidifying its market position in new applications like Liquid Biopsy and BioPharma partnerships.
- Strong Future Growth Momentum: CEO Jurgi Camblong highlighted that with the launch of new applications and expansion in the U.S. market, the business momentum remains robust, which will serve as a major catalyst for future growth and enhance the company's operational leverage.
- Transparency in Non-IFRS Reporting: The company emphasizes the use of non-IFRS measures in its financial reporting to provide investors with a clearer understanding of its operational performance, acknowledging the limitations of these metrics while still offering valuable insights into the company's future financial health.
See More
SOPHiA GENETICS Partners with Mount Sinai to Advance Cancer Research
- Collaboration Enhances Cancer Research: SOPHiA GENETICS announced a partnership with Mount Sinai Health System to adopt the AI-driven SOPHiA DDM™ platform, aimed at advancing cancer research and genomic testing capabilities, supporting care for over 4,000 oncology patients annually.
- Efficiency Optimization through Technology Integration: Mount Sinai's Molecular Pathology team will leverage SOPHiA DDM™ to enhance next-generation sequencing capabilities for blood cancers and solid tumors, significantly reducing manual interpretation time by consolidating critical steps in the analysis pipeline, thereby improving operational efficiency.
- Global Network Expansion: Mount Sinai joins a network of over 990 global institutions utilizing SOPHiA DDM™ to accelerate precision medicine, reflecting SOPHiA GENETICS' mission to democratize data-driven medicine and improve patient outcomes worldwide.
- Commitment to Scientific Innovation: The Director of Molecular Oncology Pathology at Mount Sinai stated that this collaboration reinforces the hospital's commitment to scientific innovation by integrating powerful digital tools into workflows, supporting high-quality, data-driven cancer care, and enhancing testing turnaround times to improve patient care quality.
See More
SOPHiA GENETICS (SOPH) Q4 2025 Earnings Transcript
See More
SOPHiA Genetics Q4 Earnings Report Analysis
- Earnings Performance: SOPHiA Genetics reported a Q4 GAAP EPS of -$0.28, missing the expected -$0.26, indicating ongoing challenges in profitability that may affect investor confidence.
- Revenue Growth: The company achieved Q4 revenue of $21.7 million, a 22.4% year-over-year increase, surpassing market expectations of $21.6 million, suggesting strong market demand in genomics that could lay the groundwork for future growth.
- Market Reaction: Despite the revenue beat, the EPS miss may pressure the stock price in the short term, prompting investors to monitor the company's future profitability improvement strategies to assess its long-term investment value.
- Strategic Outlook: SOPHiA Genetics needs to demonstrate stronger profitability and sustained revenue growth in upcoming reports to bolster market confidence and attract more investors, particularly in the highly competitive genomics market.
See More
SOPHiA GENETICS Reports Strong Q4 and FY 2025 Results
- Significant Revenue Growth: In Q4 2025, SOPHiA GENETICS reported a 22% year-over-year revenue increase, with a full-year growth of 19%, indicating robust momentum in the precision medicine sector that is expected to enhance shareholder value further.
- Margin Improvement: The adjusted gross margin for 2025 expanded by 140 basis points to 74.2%, even as total terabytes processed by the platform increased by 40%, demonstrating significant progress in cost control and operational efficiency.
- Customer Base Expansion: The company signed 124 new customers in 2025 and partnered with two major integrated health systems in the U.S., expected to add 60,000 analyses annually, laying a solid foundation for future revenue growth.
- Positive Future Outlook: SOPHiA GENETICS anticipates continued execution of growth strategies in the U.S. market in 2026, expansion of its Liquid Biopsy application MSK-ACCESS®, and renewed momentum in its BioPharma business, showcasing strong market potential and sustainable growth capabilities.
See More
SOPHiA GENETICS Expands U.S. Healthcare Network with Major Partnerships
- Partnership Expansion: SOPHiA GENETICS has partnered with two major U.S. healthcare systems to provide genomic testing for up to 60,000 patients annually, significantly enhancing diagnostic speed and personalized care for hereditary cancers and rare diseases.
- Technology Application Upgrade: The collaboration will leverage the SOPHiA DDM™ platform for comprehensive exome analysis of over 20,000 genes, optimizing laboratory workflows to accelerate testing turnaround times and reduce operational costs, thereby fostering internal research and innovation.
- Market Demand Response: This partnership highlights the growing need for AI-driven genomic solutions, as SOPHiA GENETICS integrates advanced bioinformatics and the collective knowledge of a global community to help healthcare institutions unlock deeper clinical insights.
- Future Development Potential: The collaboration provides both organizations with a scalable foundation to support future expansion of AI-driven precision medicine, expected to serve nearly one million cancer and rare disorder patients, further solidifying SOPHiA GENETICS' influence in the U.S. market.
See More
