Rallybio to Acquire Avenzo for $215 Million
Rallybio Corporation and Avenzo Therapeutics entered into a definitive agreement pursuant to which Rallybio will acquire Avenzo through a merger transaction. Upon completion of the Merger, the combined company is expected to operate under the name Avenzo Therapeutics, Inc. and is expected to trade on Nasdaq under the ticker symbol "AVZO". In connection with the Merger, Avenzo entered into subscription agreements for a concurrent oversubscribed private placement financing of $215 million in gross proceeds. The Financing included participation from new investors including a leading mutual fund, Blackstone Multi-Asset Investing, accounts advised by T. Rowe Price Investment Management, Inc., a leading life sciences fund, Vivo Capital, Affinity Asset Advisors, ADAR1 Capital Management, and existing investors including OrbiMed, SR One, Foresite Capital, Surveyor Capital, Longwood Fund, New Enterprise Associates, Deep Track Capital, Sands Capital, Lilly Asia Ventures, Sofinnova Investments, and other institutional investors. The combined company expects its cash balance at closing to fund operations into late 2028 and support advancement of its four clinical-stage programs through multiple clinical milestones, including updated Phase 1 data across the pipeline, initial clinical data for the combination of AVZO-023 and AVZO-021 with fulvestrant, and the initiation of multiple Phase 2 studies across the pipeline. The Transaction has been unanimously approved by the boards of directors of both companies and is expected to close in Q4 2026, subject to certain closing conditions, including the approval by the stockholders of each company, the effectiveness of a registration statement to be filed with the Securities and Exchange Commission to register the shares of Rallybio common stock to be issued in connection with the Transaction, and the satisfaction of other customary closing conditions. Rallybio intends to distribute substantially all of its pre-closing net cash to its pre-closing stockholders in connection with the Transaction. Accordingly, following closing, pre-Transaction Rallybio equityholders are expected to own approximately 2.8% of the combined company, and pre-Transaction Avenzo equityholders are expected to own approximately 97.2% of the combined company, calculated on a treasury stock method basis and assuming Rallybio has no net cash at closing. In addition, pre-closing Rallybio stockholders will receive contingent value rights entitling them to the net cash proceeds received by the combined company from the previously announced sale of interests in Rallybio's former REV102 program and potential disposition of Rallybio's other legacy assets. The combined company will be led by Dr. Athena Countouriotis, Chair, President and CEO of Avenzo, with Dr. Mohammad Hirmand, Co-founder and Chief Medical Officer of Avenzo, and an experienced management team that brings deep expertise in oncology drug development. Pro-forma cash at closing is expected to fund the combined company through multiple anticipated clinical milestones in 2027 and 2028. Under the terms of the merger agreement, Rallybio will acquire Avenzo pursuant to the Merger. At the closing of the Merger, Avenzo stockholders will receive newly issued shares of Rallybio common stock, with the exchange ratio to be determined based on the relative valuations of the two companies at closing. Immediately following the closing of the Merger, the combined company will change its name to Avenzo Therapeutics, Inc. and trade on Nasdaq under the ticker symbol "AVZO". In connection with the Transaction, a syndicate of leading healthcare institutional investors and mutual funds has committed to invest $215 million in the Financing. The Financing is expected to close immediately prior to the Merger. In connection with the Transaction, certain stockholders of Avenzo and Rallybio have executed support agreements, pursuant to which they have agreed to vote all their shares of capital stock in favor of the Transaction.
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- Financing Amount: Avenzo Therapeutics successfully secured $215 million in private placement financing from investors including Vivo Capital, Lilly Asia Ventures, and Blackstone Multi-Asset Investing, with proceeds expected to fund operations into late 2028 and support several upcoming clinical milestones.
- Merger Structure: The merger with RallyBio will result in existing Avenzo shareholders owning approximately 97.2% of the combined company, while RallyBio shareholders will hold about 2.8%, enhancing Avenzo's market position in oncology treatments.
- Product Portfolio: The combined firm will possess four clinical-stage oncology programs, including AVZO-021 and AVZO-023 for breast cancer, as well as AVZO-1418 and AVZO-103, which are being studied across multiple tumor types, thereby enriching its therapeutic pipeline.
- Market Reaction: Despite RallyBio's stock surging over 20% following the merger announcement, retail sentiment on Stocktwits remains bearish, indicating market concerns about the company's future prospects.

Termination Fee: Rally Bio Corp is set to pay a $50 million termination fee.
Additional Fees: The company will also incur $375,000 in fees related to the termination.
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