NRx Pharmaceuticals Responds to Kadima's False Claims
NRx Pharmaceuticals issued the following statement in response to recent public claims made by Kadima Neuropsychiatry Institute. "Kadima issued a public statement on June 24, 2026 making a series of unfounded allegations related to the non-acquisition of Kadima by HOPE Therapeutics, Inc., a majority-owned subsidiary of the Company. As disclosed in recent filings with the Securities and Exchange Commission, NRx has compelled arbitration with Kadima over Kadima's failure to meet key closing conditions contemplated in the related transaction documents including, but not necessarily limited to, the delivery of clear title to Kadima's assets and a material adverse change in the condition of the business. Kadima signed a binding arbitration agreement and entered into active arbitration in which the parties clearly intended to separate from one another. Management believes that specific performance, whereby HOPE would acquire Kadima and retain Dr. Feifel as HOPE's Chief Medical Innovation Officer, would not be in the best interests of either the patients or shareholders of the Company and HOPE. Moreover, despite Kadima's allegations, management does not believe that the acquisition or non-acquisition of any individual clinic would be material to HOPE's overall business model. Rather, the future success of the Company and HOPE depends on its ability to develop new drugs and medical technologies with national and international reach that deliver superior outcomes for patients affected by depression, PTSD and other serious medical conditions in need of care. Subsequent to the commencement of the arbitration by and between the Company and Kadima, the scientific direction of HOPE evolved to align more closely with current thought leaders in support of precise, personalized medicine with a particular emphasis on neuronavigated Transcranial Magnetic Stimulation used in conjunction with neuroplastic drugs, such as NRX-101. To that end, the Company continues to execute on new initiatives including a partnership with Zeta Surgical, which demonstrated the first fully functional robotic neuronavigated TMS system with submillimeter precision at the recent Clinical Transcranial Magnetic Stimulation Society meeting and subsequent treatment of the first patients at HOPE locations in Florida, as well as the recently announced FDA clearance of the Investigational New Drug application for the SPARC-TMS trial combining NRX-101 with robotic neuronavigated TMS to be conducted at civilian and military treatment facilities starting in the fall in support of recently published peer-reviewed studies that suggest the neuroplastic properties of D-cycloserine has the potential to significantly augment the effects of TMS. While NRx appreciates Dr. Feifel's desire to be part of the HOPE network as evidenced by yesterday's attempt to compel HOPE Therapeutics to incorporate his practice into the HOPE network, management does not believe that such litigation is likely to be a valid venue. Moreover, the Company does not believe that Dr. Feifel's professional experience and orientation remain aligned with HOPE's current scientific direction. We are confident that Dr. Feifel and his counsel will be directed back to arbitration by the San Diego courts and that this matter will be resolved equitably in a manner that is non-material to NRx and its shareholders. We wish Dr. Feifel the best of success in his future endeavors."
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- Treatment Launch: NRx Pharmaceuticals' subsidiary HOPE Therapeutics has initiated treatment for patients with major depressive disorder using the FDA-cleared Zeta TMS Navigation Systems at clinics in West Palm Beach and Sarasota, marking a transition from research deployment to active patient care.
- Technological Advantage: The Zeta TMS Navigation System employs proprietary RealTrack technology to provide real-time, markerless image guidance in under two minutes, continuously tracking the TMS coil's position relative to the targeted brain region with sub-millimetric accuracy, significantly enhancing treatment precision.
- Platform Expansion: This milestone not only expands HOPE's broader interventional psychiatry platform, which includes ketamine and Spravato delivery, TMS, and Hyperbaric Oxygen Therapy, but also aims to provide a more comprehensive treatment approach for patients with major depressive disorder and other neurological conditions.
- Future Plans: NRx plans to utilize this platform in its upcoming SPARC-TMS trial evaluating NRX-101, a combination of oral D-cycloserine and lurasidone, in patients with depression and suicidality across civilian and military treatment facilities, further diversifying its treatment offerings.
- First Patient Treatments: HOPE Therapeutics has successfully initiated its first Zeta-navigated TMS treatments at clinics in West Palm Beach and Sarasota, Florida, marking a significant transition from research deployment to active patient care, which is expected to greatly enhance treatment outcomes for patients.
- AI Technology Implementation: The Zeta TMS Navigation System employs artificial intelligence and computer vision to provide sub-millimetric image guidance, enabling the registration of a patient's MRI or CT imaging to their facial anatomy in under two minutes, thereby improving treatment precision and efficiency.
- Support for Clinical Trials: The implementation of these treatments aligns with NRx's planned trial of NRX-101 in civilian and military treatment facilities, indicating ongoing advancements in HOPE's interventional psychiatry platform and enhancing its competitiveness in treating patients with depression and suicidality.
- Integrated Treatment Model: HOPE's treatment platform not only includes TMS but also incorporates various therapies such as ketamine and Spravato®, aiming to provide a more comprehensive solution for treatment-resistant depression patients, further solidifying its leadership position in the mental health sector.
- Lawsuit Background: Kadima Neuropsychiatry Institute and founder Dr. David Feifel have filed a lawsuit against NRx Pharmaceuticals and its subsidiaries in San Diego County Superior Court, alleging breach of contract and misrepresentation in connection with an acquisition agreement, seeking a court order to compel the defendants to close the transaction, which represents a significant percentage of NRx's current market capitalization.
- Missing Financing Commitment: NRx Chairman Dr. Jonathan Javitt approached Dr. Feifel in 2024 with a proposal to acquire Kadima, repeatedly assuring that financing was secured, yet failed to provide sufficient funds as stipulated in the Asset Purchase Agreement signed on May 9, 2025, impacting the acquisition plans.
- Stock Price Volatility: NRx's press release on January 2, 2025, did not mention any financing contingencies, causing its stock to surge over 40% in a single day; however, subsequent statements indicated that the transaction was still subject to
- FDA-Cleared Treatment System: ZETA SURGICAL and HOPE Therapeutics have announced the first patient treatment using the FDA-cleared Zeta TMS Navigation System at their Florida clinics, marking a significant advancement in psychiatric treatment that is expected to improve outcomes and enhance patients' quality of life.
- Precision Navigation Technology: The Zeta TMS Navigation System utilizes RealTrack™ technology to provide real-time, markerless image guidance by registering a patient's MRI or CT imaging to their facial anatomy in under two minutes, ensuring high accuracy and repeatability in treatment delivery, thereby enhancing treatment efficacy.
- Multi-Site Implementation: HOPE Therapeutics has installed the Zeta TMS Navigation System at clinics in West Palm Beach and Sarasota, with patient treatments commencing this week, which is anticipated to expand access to personalized TMS therapy and address the needs of patients with treatment-resistant depression.
- Commitment from Industry Leaders: Raahil Sha, Co-Founder of ZETA, stated that the introduction of the Zeta TMS Navigation System will bring surgical-grade accuracy to TMS clinics, driving the ongoing evolution of psychiatric care and improving patient treatment experiences and outcomes.
- First Patient Treatment: ZETA SURGICAL and HOPE Therapeutics successfully conducted the first patient treatment with the FDA-cleared Zeta TMS Navigation System at their Sarasota clinic, marking a significant milestone in precision treatment for depression.
- Technological Innovation: The Zeta TMS Navigation System utilizes RealTrack™ technology to provide real-time, markerless image guidance by registering a patient's MRI or CT imaging to their facial anatomy in under two minutes, ensuring high accuracy and reliability in treatment delivery.
- Expanded Treatment Access: The system has been implemented at HOPE's clinics in West Palm Beach and Sarasota, expected to offer personalized TMS therapy to more patients with treatment-resistant depression, thereby enhancing patient quality of life.
- Industry Impact: Raahil Sha, Co-Founder of ZETA, stated that the application of this technology will transform psychiatric care by improving treatment accuracy and personalization, further expanding the clinical applications of TMS across the country.








