Indivior Pharmaceuticals to Present New Research Posters at American Society of Addiction Medicine Annual Conference
Indivior Pharmaceuticals will present one new scientific poster and collaborated with VA Tech on a second poster which will be presented at the American Society of Addiction Medicine Annual Conference, held April 23-26, 2026, in San Diego, California. The data add to the growing body of evidence evaluating extended-release buprenorphine, a monthly injectable commercially available as SUBLOCADE, in supporting meaningful outcomes for people living with OUD, including overdose-related outcomes and broader indicators associated with recovery. Impact of OAT in individuals with OUD who experienced an overdose in Ontario, Canada: This retrospective nested case-control study used Ontario administrative health data of more than 45,000 patients with OUD to evaluate associations between MOUD treatments, including SUBLOCADE, transmucosal buprenorphine, methadone, and sustained-release oral morphine and the risk of opioid-related fatal and non-fatal overdose. Most overdose events occurred off treatment: Patients with higher MOUD coverage experienced less non-fatal and fatal overdose compared to those with lower MOUD coverage. Buprenorphine-based MOUD significantly reduced overdose risk: Of all MOUD, SUBLOCADE accounted for the smallest proportion of non-fatal and fatal OD events compared to no treatment. Both SUBLOCADE and TM-BUP had the lowest odds of all MOUD odds of non-fatal and fatal overdose versus no MOUD. Study limitations include potential misclassification in administrative data, incomplete or inaccurate capture of opioid-related OD events and OAT use, and absence of a direct measure of OAT adherence. Associations between remission from opioid use disorder and treatment-relevant outcomes: Provisional findings from the Remission from OUD as a Treatment Endpoint followed 443 participants within 0-3 months of starting treatment with SUBLOCADE for up to 12 months to understand how OUD remission relates to treatment-relevant and recovery-related outcomes. Remission as an indicator of improved outcomes: Individuals entering the study in remission for 3-months indicated lower craving, lower withdrawal, lower pain, better quality of life, and lower rates of unemployment than those not in remission. Complete abstinence may neither be sufficient nor necessary: Opioid misuse and OUD remission are not always consistent; an individual may abstain from opioid misuse while not yet meeting criteria for 3-month remission, underscoring the importance of remission as a clinically meaningful treatment endpoint. One study limitation is that participants entered at varying BUP-XR treatment durations, so study entry does not align with treatment initiation.
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- New Investment Position: Claret Asset Management established a new position in Indivior during Q1 2026 by acquiring 707,267 shares valued at $23.36 million, indicating strong confidence in the company's growth potential.
- Holding Value Fluctuation: By the end of the quarter, Claret's holding in Indivior was valued at $21.56 million, reflecting market price changes and adjustments in asset allocation post-acquisition, thereby enhancing portfolio diversity.
- Significant Performance Growth: Indivior reported a 19% year-over-year revenue increase to $317 million in Q1, with Sublocade sales surging 32% to $232 million, demonstrating robust market demand for opioid dependence treatments.
- Strategic Buybacks: Indivior repurchased approximately 4 million shares for $125 million during the quarter and announced a $175 million accelerated share repurchase agreement with Barclays, reflecting confidence in its stock price and future growth expectations.
- Repurchase Agreement Details: Indivior has entered into a $175M accelerated share repurchase agreement with Barclays, expecting an initial delivery of 3,717,473 shares, reflecting the company's confidence in its stock value.
- Funding Arrangement: This repurchase will be executed under Indivior's existing $400M share repurchase program, indicating a proactive strategy in capital management aimed at enhancing shareholder returns.
- Financial Impact: Indivior does not expect this repurchase to affect its previously issued financial guidance, demonstrating the company's commitment to maintaining financial stability.
- Future Repurchase Potential: Following this repurchase, Indivior retains an additional $100M under its repurchase authorization, allowing for further buybacks based on market conditions, which could further bolster shareholder confidence.
- Repurchase Agreement Details: Indivior Pharmaceuticals has signed a $175 million accelerated share repurchase agreement with Barclays, part of its $400 million buyback program, with final settlement expected by the end of June, reflecting the company's confidence in its long-term strategy.
- Initial Delivery Quantity: The company will make an upfront payment of $175 million and expects an initial delivery of approximately 3.72 million shares, with the final number of shares repurchased based on the volume-weighted average price during the agreement term, ensuring flexibility and market adaptability in the buyback process.
- Remaining Buyback Funds: Following this agreement, Indivior has an additional $100 million under its share repurchase authorization for further buybacks, indicating a proactive approach to capital management aimed at enhancing shareholder value.
- Market Reaction: In pre-market trading on Nasdaq, Indivior shares rose by 3.27% to $38.89, reflecting a positive market response to the company's buyback plan, which may further bolster investor confidence.
- Research Presentation: Indivior showcased collaborative research with Virginia Tech at the American Society of Addiction Medicine annual conference, highlighting the efficacy of extended-release buprenorphine (SUBLOCADE®) in improving quality of life and reducing overdose risks for opioid use disorder patients, thereby reinforcing its leadership in the opioid treatment sector.
- Reduced Overdose Risk: The study indicates that patients treated with buprenorphine had the lowest proportions of non-fatal and fatal overdose events, particularly when treatment coverage exceeded 80%, providing crucial evidence for clinical practice regarding effective treatment strategies.
- Importance of Remission Indicators: In a study involving 443 participants, those entering remission showed better outcomes in terms of reduced cravings, withdrawal symptoms, and improved quality of life, emphasizing the significance of remission as a treatment endpoint beyond mere abstinence criteria.
- Long-term Commitment: Indivior's Chief Scientific Officer stated that for 25 years, the company has been dedicated to advancing science that improves care for opioid use disorder patients, demonstrating ongoing efforts to promote effective treatment and expand access to quality care.
- Survey Overview: Indivior's survey reveals that 88% of jail staff and 87% of prison personnel believe that long-acting injectable buprenorphine can effectively reduce medication for opioid use disorder (MOUD) diversion, indicating its potential in correctional settings.
- Implementation Barriers Identified: The survey also highlights structural barriers to effective MOUD program implementation, including inadequate medical and custody staffing, limited coordination between health services and custody, and operational challenges related to medication administration and monitoring, which hinder effective treatment delivery.
- Policy Recommendations: The findings underscore the need for policies and funding strategies to strengthen staffing capacity, enhance care coordination, and ensure sustainable MOUD delivery during incarceration and throughout reentry into the community, thereby supporting long-term recovery.
- Industry Impact: Indivior executives emphasize that simplified treatment models can improve patient access while enhancing institutional operational efficiency, reinforcing the significance of long-acting injectable buprenorphine as a viable implementation strategy.
- Staff Time Savings: The use of SUBLOCADE® in correctional facilities results in a reduction of 318 staff hours per month compared to methadone, significantly lowering labor costs and enhancing operational efficiency to address staffing shortages.
- Significant Cost Benefits: Monthly cost savings range from $23 to $22,148, with the largest savings stemming from the elimination of daily observed dosing and patient escorts, indicating SUBLOCADE®'s economic advantages.
- Improved Treatment Efficiency: Compared to other medications, SUBLOCADE®'s monthly injections reduce reliance on staff, enabling prisons to provide evidence-based care more efficiently and meet the growing demand for opioid use disorder treatment.
- Support for Policy Goals: Indivior's research underscores the potential of more efficient medication delivery models to advance public policy goals and improve health outcomes, highlighting SUBLOCADE®'s strategic significance in public health.









