Immuneering Reports 64% Survival Rate in Phase 2a Trial for Pancreatic Cancer Drug
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 08 2026
0mins
Source: NASDAQ.COM
- Survival Rate Improvement: In the ongoing Phase 2a trial, the combination of Atebimetinib with modified gemcitabine/nab-paclitaxel achieved a 64% overall survival rate at 12 months, significantly higher than the historical 35% observed with standard treatments, indicating the drug's potential in pancreatic cancer therapy.
- Clinical Trial Scale: The trial enrolled 34 patients with first-line metastatic pancreatic cancer, evaluating overall survival and progression-free survival; while the median overall survival has not yet been reached, the median progression-free survival was 8.5 months, suggesting the drug may enhance patient quality of life.
- Future Development Plans: Immuneering plans to initiate the pivotal Phase 3 trial MAPKeeper 301 in mid-2026, aimed at confirming survival benefits and potentially establishing Atebimetinib as a new standard of care, reflecting the company's confidence and market potential for the drug.
- Strong Financial Position: As of September 30, 2025, Immuneering reported $227.6 million in cash and cash equivalents, providing sufficient resources to fund operations into 2029, demonstrating the company's financial stability in advancing its R&D efforts.
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Analyst Views on IMRX
Wall Street analysts forecast IMRX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for IMRX is 14.50 USD with a low forecast of 11.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
4 Analyst Rating
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 4.870
Low
11.00
Averages
14.50
High
20.00
Current: 4.870
Low
11.00
Averages
14.50
High
20.00
About IMRX
Immuneering Corporation is a clinical-stage oncology company. The Company is engaged in the development of medicines for cancer patients with universal-RAS therapy. The Company’s lead product candidate, IMM-1-104, is in under Phase I/IIa clinical trial in patients with advanced solid tumors harboring RAS mutations. IMM-1-104 is being developed as a once-daily oral monotherapy that aims to achieve universal-RAS activity through deep cyclic inhibition of the mitogen-activated protein kinase (MAPK) pathway. The Company’s second product candidate, IMM-6-415, is an oral, twice-daily deep cyclic inhibitor of mitogen-activated protein kinase kinase (MEK) in a Phase I/IIa trial in patients with advanced solid tumors harboring RAS or RAF mutations. Its pipeline also includes RAS modulators and other small molecule drug discovery programs. The Company’s platform is enabled by two key elements: Bioinformatics and 3D Tumor Modeling.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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