GeneDx Q4 Earnings Exceed Expectations with Strong Guidance
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 18 hours ago
0mins
Should l Buy WGS?
Source: seekingalpha
- Strong Earnings Performance: GeneDx reported a Q4 non-GAAP EPS of $0.18, beating expectations by $0.06, which reflects the company's ongoing improvement in profitability and boosts investor confidence.
- Significant Revenue Growth: The company achieved $121 million in revenue for Q4, representing a 27% year-over-year increase and exceeding market expectations by $560,000, indicating robust demand in the genomics market and an increase in market share.
- Positive 2026 Outlook: Management anticipates revenue for 2026 to be between $540 million and $555 million, surpassing the consensus estimate of $542.99 million, showcasing confidence in future growth, particularly with expected increases of 33% to 35% in exome and genome revenue.
- Margin and Income Expectations: The company expects an adjusted gross margin of at least 70% and positive adjusted net income, demonstrating effective strategies in cost control and profitability, which further solidifies its market position.
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Analyst Views on WGS
Wall Street analysts forecast WGS stock price to rise
8 Analyst Rating
7 Buy
1 Hold
0 Sell
Strong Buy
Current: 82.060
Low
155.00
Averages
171.43
High
200.00
Current: 82.060
Low
155.00
Averages
171.43
High
200.00
About WGS
GeneDx Holdings Corp. is a genomics company. The Company operates, through its subsidiary, GeneDx, LLC, which is focused on exome and genome tests that translate complex genomic data into clinical answers that unlock personalized health plans, accelerate drug discovery, and improve health system efficiencies. It operates through GeneDx segment, which primarily provides pediatric and rare disease diagnostics with a focus on whole exome and genome sequencing and, to a lesser extent, data and information services. Exome sequencing test options include XomeDx, XomeDx Plus, and XomeDxXpress. GeneDx genome sequencing evaluates the protein-coding and non-coding regions of an individual’s nuclear genome. GeneDx genome sequencing test options include GenomeSeqDx and GenomeXpress. It offers a menu of targeted variant testing options to meet the needs of families and healthcare providers. Its subsidiary, Fabric Genomics, Inc., specializes in artificial intelligence-powered genomic interpretation.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Stock Performance: Shares of Genedx Holdings increased by 3.5% in pre-market trading following the release of their Q4 results.
- Earnings Report: The company's Q4 results exceeded market expectations, contributing to the positive movement in their stock price.
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- Strong Financial Performance: GeneDx reported Q4 2025 revenues of $121 million, a 27% year-over-year increase, with exome and genome revenues reaching $104 million, up 32%, indicating robust market demand in rare disease diagnostics.
- Market Expansion Plans: The company plans to expand its sales force from 50 to 75 representatives, focusing on foundational and emerging markets, which is expected to significantly enhance market penetration and capture future growth opportunities.
- Optimistic Future Outlook: GeneDx reaffirmed its 2026 revenue guidance of $540 million to $555 million, with exome and genome growth projected at 33% to 35%, reflecting confidence in the market potential.
- Innovative Data Set Advantage: The Infinity data set is touted as the
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- Strong Earnings Report: GeneDx's Q4 2025 results revealed a non-GAAP EPS of $0.18, beating expectations by $0.06, while revenue reached $121 million, exceeding market forecasts by $560,000, indicating robust profitability and market demand.
- Optimistic Revenue Guidance: The company projects 2026 revenue between $540 million and $555 million, surpassing the consensus of $542.99 million, reflecting strong confidence in future growth and potential stock price appreciation.
- Significant Testing Volume Growth: GeneDx reported a 34.3% year-over-year increase in exome and genome test result volume, reaching 27,761, demonstrating strong market demand and further solidifying its leadership position in the genetic testing sector.
- Analysts Bullish on Future: TD Cowen's analyst rates GeneDx as a buy with a price target of $165, indicating a potential upside of 101%, while Canaccord's analyst sets a target of $170, showcasing optimistic market expectations for the company's future growth.
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- Strong Earnings Performance: GeneDx reported a Q4 non-GAAP EPS of $0.18, beating expectations by $0.06, which reflects the company's ongoing improvement in profitability and boosts investor confidence.
- Significant Revenue Growth: The company achieved $121 million in revenue for Q4, representing a 27% year-over-year increase and exceeding market expectations by $560,000, indicating robust demand in the genomics market and an increase in market share.
- Positive 2026 Outlook: Management anticipates revenue for 2026 to be between $540 million and $555 million, surpassing the consensus estimate of $542.99 million, showcasing confidence in future growth, particularly with expected increases of 33% to 35% in exome and genome revenue.
- Margin and Income Expectations: The company expects an adjusted gross margin of at least 70% and positive adjusted net income, demonstrating effective strategies in cost control and profitability, which further solidifies its market position.
See More
- Significant Revenue Growth: GeneDx reported Q4 2025 revenues of $121 million, reflecting a 27% year-over-year increase, with exome and genome test revenues growing by 32%, indicating strong demand and market expansion in genomic diagnostics.
- Margin Improvement: The adjusted gross margin for Q4 reached 71%, up from 70% in Q4 2024, showcasing the company's ongoing improvements in cost control and operational efficiency, which enhance profitability.
- Net Income Recovery: The adjusted net income for Q4 2025 was $4.4 million, although down from $17.5 million in Q4 2024, it still demonstrates the company's ability to maintain profitability amidst challenges, indicating resilience in its business model.
- Optimistic 2026 Outlook: GeneDx reaffirmed its revenue guidance for 2026 at $540 to $555 million, with expected growth rates for exome and genome testing between 33% and 35%, reflecting confidence in future market opportunities and clear strategic planning.
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