Galapagos Presents New GLPG5101 Data with 100% Response Rate in MCL Patients
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 08 2025
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Source: Globenewswire
- Significant Response Rate: In the ATALANTA-1 study, 25 MCL patients treated with GLPG5101 achieved a 100% objective response rate, with 96% attaining complete responses, highlighting the therapy's efficacy and potential market appeal in high-risk populations.
- Rapid Treatment Cycle: The vein-to-vein time for GLPG5101 is only seven days, resulting in a low dropout rate of 4% and eliminating the need for bridging therapy, thereby increasing access to CAR T-cell therapy for more patients and enhancing treatment accessibility.
- Good Safety Profile: Among the 24 treated patients, no Grade ≥ 3 cytokine release syndrome (CRS) was observed, and only one case of Grade ≥ 3 neurological adverse event occurred, indicating that GLPG5101 has a favorable safety profile, which may boost patient confidence in treatment.
- Strategic Transformation: Galapagos intends to wind down its cell therapy activities while continuing clinical studies and considering acquisition proposals, demonstrating the company's ongoing focus on its core business during this transformation phase.
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Analyst Views on GLPG
Wall Street analysts forecast GLPG stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for GLPG is 30.50 USD with a low forecast of 22.00 USD and a high forecast of 40.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
4 Analyst Rating
1 Buy
1 Hold
2 Sell
Hold
Current: 34.100
Low
22.00
Averages
30.50
High
40.00
Current: 34.100
Low
22.00
Averages
30.50
High
40.00
About GLPG
Galapagos NV is a Belgium-based clinical-stage biotechnology company. The Company is engaged in the discovery and development of small molecule medicines with modes of action. Its pipeline comprises Phase 3, 2, 1, pre-clinical studies and discovery small-molecule and antibody programs in cystic fibrosis, inflammation, and other indications. The Company focuses on developing a portfolio of clinical-stage therapies for the enhancement of existing treatment paradigms. It develops transformational medicines in areas of high unmet need by combining internal with external science with the goal to add years of life and improve of life of patients across the globe. It discovers which proteins that are involved in causing diseases such as, rheumatoid, arthritis, inflammatory bowel disease and fibrosis. The Company acquired CellPoint and AboundBio in order to develop a cell therapy, which is a potential transformative treatment of different types of cancer.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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