Cellares and Cabaletta Bio Infuse CAR T Cell Therapy for First Patients

Cellares announced that Cabaletta Bio Inc.'s investigational CAR T cell therapy rese-cel has been infused into the first two patients using drug product manufactured on Cellares' Cell Shuttle automated manufacturing platform. The administration of an autologous cell therapy, which met all release criteria and was manufactured on an automated manufacturing platform, represents an important step on the journey to realizing a future where scalable manufacturing of autologous products to supply thousands of patients per year can be achieved with minimal capital investment and a low cost of goods. "This is an important milestone that reflects focused collaboration between the teams at Cabaletta and Cellares since 2023," said Steven Nichtberger, M.D., Co-founder, Chairman, and Chief Executive Officer of Cabaletta Bio. "The dosing of these first two patients is an important demonstration of Cellares' GMP manufacturing and supply chain capabilities with their automated manufacturing platform and thus represents a significant achievement towards our goal of securing high-capacity flexible supply with minimal capital investment and a low cost of goods."