Carlsmed Completes First Spine Surgery Using Aprevo System
Carlsmed announced the successful completion of the first posterior lumbar spine surgery using the Company's aprevo Lumbar Bi-lateral Posterior System. The procedure was performed by Orthopedic Spine Surgeon CJ Kleck, M.D. at the University of Colorado Hospital in Denver, Colorado. "This clinical milestone strengthens our position as a leader in personalized, data-driven spine solutions designed to help surgeons plan with greater precision, improve patient outcomes, and reduce costly revisions. The addition of the aprevo(R) Bi-lateral Posterior Lumbar Interbody Fusion procedure to our personalized surgery procedure portfolio further demonstrates the power and versatility of our personalized, AI-enabled approach to spine surgery," said Mike Cordonnier, Chairman and CEO of Carlsmed. "We look forward to our full commercial launch this year to provide this personalized procedural option to patients, surgeons, and hospital systems on a larger scale."
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- Surgical Milestone: Carlsmed successfully performed the first personalized cervical plating procedure at UCSF, marking a significant advancement for its corra Cervical Plating System and boosting positive sentiment around its stock.
- Product Innovation: The corra system aims to enhance surgical precision and improve patient outcomes by utilizing patient-specific plates tailored to individual anatomical needs, with plans for further evaluations and a commercial launch later this year.
- Digital Surgery Ecosystem: Leveraging Carlsmed's digital surgery ecosystem, the system customizes key anatomical features, including screw positioning and plate curvature, pre-operatively for each vertebral level, supporting consistent fixation and precise alignment for ACDF procedures.
- Wall Street Optimism: Carlsmed's stock carries a Buy rating with an average price target of $20.25, with analysts from BTIG and Truist Securities raising their targets to $24.00 and $20.00 respectively, reflecting confidence in the company's future performance.
- Earnings Report Schedule: Carlsmed will release its Q4 and full year 2025 financial results after market close on February 25, 2026, providing investors with the latest insights into the company's operational performance.
- Conference Call Details: Management will host a conference call and webcast at 1:30 PM Pacific Time, with participants encouraged to dial in 5 to 10 minutes early to ensure they receive timely updates on company developments.
- Replay Availability: A replay of the webcast will be available shortly after the call concludes, allowing investors who could not attend live to review the meeting content, thereby enhancing information transparency.
- Company Mission: Carlsmed is committed to improving healthcare outcomes and reducing costs for spine surgery through AI-enabled personalized solutions, showcasing its innovative potential and competitive edge in the medical technology sector.
- Layoff Plan: Heineken plans to cut 5,000 to 6,000 jobs over the next two years, representing about 7% of its 87,000 workforce, aiming to enhance productivity in response to a 2.4% decline in beer sales last year.
- Profit Growth Target: Despite the drop in total beer volumes, Heineken's adjusted operating profit rose by 4.4%, with the company forecasting operating profit growth of 2% to 6% for 2026, demonstrating resilience in a challenging market environment.
- Digital Transformation: The layoffs are partly attributed to the push for AI and digitization, with around 3,000 roles expected to move to business services, aiming for annual savings of €400 to €500 million, further advancing its EverGreen 2030 strategy.
- Market Reaction: Heineken's shares rose 3.4% in the latest trading session, and the stock is up nearly 7% year-to-date, reflecting market confidence in its strategic adjustments and future growth potential.
- Surgical Milestone: Carlsmed successfully completed its first posterior lumbar spine surgery using the aprevo® Bi-lateral Posterior System at the University of Colorado Hospital, reinforcing the company's leadership in personalized spine solutions.
- Technological Advantage: The system integrates AI-enabled software and clinical intelligence, allowing surgeons to plan with greater precision, thereby improving patient outcomes and reducing costly revision surgeries.
- Market Outlook: Carlsmed anticipates a full commercial launch of the system later this year, aiming to provide personalized procedural options to patients, surgeons, and hospital systems, thereby expanding its market share.
- Surgeon Feedback: Dr. CJ Kleck emphasized that the aprevo® technology is crucial across all surgical stages, enabling tailored treatment based on each patient's anatomy and pathology, which enhances confidence in achieving alignment goals.
- Earnings Decline: The Danish brewer reported a decline in earnings primarily due to a softening consumer appetite for beer, which has negatively impacted overall sales and the company's financial health.
- Increased Soft Drink Reliance: In response to declining beer sales, the company is increasingly relying on its soft drink offerings, a shift that may alleviate some pressure in the short term but could affect brand image and market positioning in the long run.
- Changing Market Demand: As consumer preferences shift towards healthier beverage options, the beer industry faces significant challenges, forcing the company to reassess its product portfolio to align with new market trends.
- Need for Strategic Adjustment: Given the earnings decline, the Danish brewer must develop new strategies to enhance its competitiveness in the soft drink market while also seeking effective ways to revive beer sales.
- Sales Warning: Novo Nordisk released its earnings report early, projecting a decline in sales and profit growth this year primarily due to lower prices in the U.S. and the loss of exclusivity for its weight loss drugs Wegovy and Ozempic in China, Brazil, and Canada, which may dampen market confidence.
- Stock Reaction: Following the warning, Novo Nordisk's share price tumbled significantly, reflecting investor concerns about future performance, which could impact the company's competitiveness and investor confidence in global markets.
- Market Impact: European stocks are expected to open flat to higher, with the FTSE and DAX slightly up, and the CAC 40 rising by 0.24%, indicating a cautiously optimistic market sentiment ahead of upcoming earnings reports, despite overall sentiment being affected by a short-lived sell-off in cryptocurrencies and precious metals.
- Earnings Focus: On Wednesday, several companies including Novo Nordisk, Banco Santander, and GSK are set to report earnings, with the market closely monitoring these reports for their implications on overall economic and industry trends, especially amid increasing economic uncertainty.











