Caribou Biosciences Shares Increase by 3% Following Two Positive Phase 1 Trial Announcements
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Nov 03 2025
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Source: NASDAQ.COM
Positive Clinical Data: Caribou Biosciences reported encouraging results from its ANTLER and CaMMouflage Phase 1 trials, with its anti-CD19 CAR-T therapy achieving an 82% overall response rate and 64% complete response rate, while the anti-BCMA CAR-T therapy showed a 92% overall response rate and 75% complete response rate.
Future Plans: The company plans to initiate dose expansion for its CB-011 therapy by year-end and is designing a pivotal Phase 3 trial for its vispa-cel therapy in second-line large B-cell lymphoma patients, in coordination with the FDA.
Stock Performance: Following the announcement, Caribou's stock (CRBU) rose 3.34% to $2.5010, with significant trading volume and a daily price range between $2.40 and $2.60.
Market Context: The stock's 52-week range is noted to be approximately $1.20 to $3.50, indicating a volatile trading history and heightened investor interest following the positive trial results.
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Analyst Views on CRBU
Wall Street analysts forecast CRBU stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CRBU is 8.00 USD with a low forecast of 6.00 USD and a high forecast of 10.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
5 Analyst Rating
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 1.520
Low
6.00
Averages
8.00
High
10.00
Current: 1.520
Low
6.00
Averages
8.00
High
10.00
About CRBU
Caribou Biosciences, Inc. is a clinical-stage clustered regularly interspaced short palindromic repeats (CRISPR) genome-editing biopharmaceutical company engaged in developing transformative therapies for patients with devastating diseases. The Company’s genome-editing platform, including its Cas12a chRDNA technology, enables superior precision to develop cell therapies that are armored to potentially improve activity against disease. Caribou is advancing a pipeline of off-the-shelf cell therapies from its CAR-T platform to offer broad access and rapid availability of treatments for patients with hematologic malignancies and autoimmune diseases. Its genome-editing platform, including its novel chRDNA technology, enables more precise genome editing of allogeneic cell therapies. It is advancing its pipeline of allogeneic CAR-T cell therapies with clinical development programs targeting the treatment of hematologic malignancies and autoimmune diseases.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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