BioVie presents data on Bezisterim at WCAG-2025
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jul 24 2025
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Bezisterim's Impact on Alzheimer's Disease: BioVie presented findings at the WCAG-2025 conference indicating that bezisterim significantly decelerates biological aging in Alzheimer's patients, as evidenced by improvements in various biological clocks after 30 weeks of treatment.
Gene Modulation and Biomarker Improvements: The study showed that bezisterim modulates inflammatory gene expression, reducing cytokines like TNFalpha and IL-6, while also improving metabolic and inflammatory biomarkers related to carbohydrate metabolism and Type 2 diabetes.
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Analyst Views on BIVI
About BIVI
BioVie Inc. is a clinical-stage company developing innovative drug therapies for the treatment of neurological and neurodegenerative disorders and advanced liver disease. In neurodegenerative disease, the Company's drug candidate bezisterim inhibits inflammatory activation of extracellular signal-regulated kinase and the transcription factor nuclear factor-kB, and the associated neuroinflammation and insulin resistance, but not ERK and NFkB homeostatic functions (such as insulin signaling and neuron growth and survival). Both neuroinflammation and insulin resistance are drivers of Alzheimer’s disease (AD) and Parkinson’s disease (PD). Persistent systematic inflammation and neuroinflammation are key features in patients with neurological symptoms of long COVID. In liver disease, the Company's orphan drug candidate BIV201, is being evaluated for Phase III clinical testing for the reduction of further decompensation in participants with liver cirrhosis and ascites.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
New to The Street Broadcasts Show #716 Featuring SDST and Others
- Broadcast Timing: New to The Street will air Show #716 tonight at 6:30 PM Eastern Time on Bloomberg Television, enhancing its influence in the business media landscape by showcasing various public companies.
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- International Expansion Plans: New to The Street plans to launch its international version in the MENA region on January 24, 2026, further expanding its global reach, while also preparing to launch the Spanish-language platform Nuevo En La Calle, showcasing its diversified media strategy.
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BioVie Inc. Investigated for Potential Breach of Fiduciary Duties by Executives
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- Legal Relief Options: Long-term shareholders of BioVie may seek corporate governance reforms, fund recovery, or court-approved financial incentives, aimed at enhancing company transparency and accountability.
- Importance of Participation: Shareholder involvement can improve company policies and oversight mechanisms, thereby enhancing shareholder value and increasing the effectiveness of corporate management.
- Legal Fee Arrangement: Halper Sadeh LLC will handle the case on a contingency fee basis, meaning shareholders will not incur out-of-pocket legal fees, reducing the financial burden of participation.
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