BillionToOne Collaborates with Epic to Integrate Testing Services
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 15 2026
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Should l Buy BLLN?
BillionToOne announced a collaboration with Epic, a comprehensive electronic health record. The agreement will integrate BillionToOne's prenatal and oncology testing portfolio with Epic's Aura diagnostics suite. Through the integration, clinicians will be able to order BillionToOne's UNITY Complete prenatal test as well as Northstar Select and Northstar Response liquid biopsy tests directly within Epic. Discrete test results then flow back into the electronic health record, where they can power downstream clinical decision support.
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Analyst Views on BLLN
Wall Street analysts forecast BLLN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for BLLN is 137.83 USD with a low forecast of 110.00 USD and a high forecast of 160.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
7 Analyst Rating
5 Buy
2 Hold
0 Sell
Moderate Buy
Current: 85.150
Low
110.00
Averages
137.83
High
160.00
Current: 85.150
Low
110.00
Averages
137.83
High
160.00

No data
About BLLN
BillionToOne, Inc. is a precision diagnostics company that quantifies biology to create molecular diagnostics. The Company's proprietary molecular counting platform is designed to detect and measure deoxyribonucleic acid (DNA) molecules at a single-count level to help improve disease detection. It applies the proprietary technology to non-invasive prenatal screening (Prenatal) and liquid biopsy (Oncology). Its Quantitative Counting Templates (QCTs), power its ability to detect and measure tiny and sparse disease-related DNA fragments, or molecules, at the single base-pair level. These include pregnancy-related DNA that code for recessively inherited conditions such as sickle cell disease and cystic fibrosis and ctDNA in the case of cancer. Its prenatal products include UNITY Complete, UNITY Fetal Risk Screen, UNITY Aneuploidy Screen, UNITY Fetal RhD NIPT, UNITY Fetal Antigen NIPT, and UNITY Fetal Antigen CTA NIPT. Its oncology products include Northstar and Northstar Select.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- FY2025 Revenue Guidance: BillionToOne reiterated its FY2025 revenue guidance in the range of $293 million to $299 million, expecting to achieve positive GAAP operating income, indicating strong market performance and profitability.
- FY2026 Outlook: The company introduced its FY2026 financial guidance, projecting revenue between $415 million and $430 million, representing approximately 40% to 45% growth compared to the midpoint of the FY2025 guidance, reflecting its strategic commitment to scaling its platform.
- Profitability Expectations: BillionToOne anticipates delivering positive GAAP operating income for FY2026 as well, demonstrating confidence in its future financial health and sustainable growth.
- Market Reaction: Although BillionToOne shares slightly declined by 0.14% to $99.01 during early trading, the positive market response to its financial guidance indicates investor recognition of the company's growth potential.
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- 2025 Revenue Outlook: BillionToOne expects fiscal 2025 revenue to range between $293 million and $299 million, indicating stable growth potential in the molecular diagnostics sector, with positive net operating income anticipated.
- 2024 Performance Review: For fiscal 2024, BillionToOne reported revenue of $153 million, reflecting significant growth compared to the previous year and demonstrating the company's increasing competitiveness in the market.
- 2026 Forecast: The company anticipates revenue for fiscal 2026 to be between $415 million and $430 million, with continued positive net operating earnings expected, highlighting strong business expansion and market demand.
- Analyst Expectations: An average of eight analysts forecasts BillionToOne to generate $296.24 million in revenue for 2025 and $393.61 million for 2026, indicating market confidence in the company's future growth trajectory.
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- Liquid Biopsy Selection: BillionToOne's Northstar Select has been chosen as the liquid biopsy platform for the LC-SCRUM-TRY study, aimed at analyzing genomic characteristics of approximately 2,000 patients with treatment-resistant non-small cell lung cancer through non-invasive methods, thereby enhancing precision in treatment selection.
- Technical Advantage: The Northstar Select single-molecule NGS platform can detect variant allele frequencies as low as 0.15%, significantly outperforming other commercial liquid biopsy tests, ensuring higher sensitivity in clinical applications to meet patient demands for personalized treatment.
- Clinical Validation: The platform's performance in comparative studies with traditional tissue biopsies has led to meeting Medicare coverage criteria, indicating that more advanced cancer patients will benefit from this innovative technology, promoting the accessibility of precision medicine.
- Strategic Collaboration: The partnership with the National Cancer Center Hospital in Japan marks a significant advancement in treatment options for patients with drug-resistant lung cancer, expected to provide more effective therapies and further solidify the company's leadership in the molecular diagnostics field.
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- Liquid Biopsy Selection: BillionToOne's Northstar Select has been chosen as the liquid biopsy platform for the LC-SCRUM-TRY study, aiming to analyze genomic characteristics of approximately 2,000 advanced non-small cell lung cancer patients through a non-invasive method, thereby enhancing understanding and treatment options for drug-resistant cancers.
- Technical Advantage: The single-molecule NGS platform of Northstar Select detects variant allele frequencies as low as 0.15%, significantly outperforming other liquid biopsy tests, ensuring higher sensitivity in clinical applications to meet the urgent precision medicine needs of lung cancer patients in Japan.
- Clinical Validation: In the LC-SCRUM-Asia genetic screening study, Northstar Select demonstrated its accuracy by comparing tumor tissue and plasma samples from about 1,000 patients, facilitating its broader adoption in Japan.
- Medicare Coverage: The test has met Medicare coverage criteria, ensuring that more advanced cancer patients can access personalized treatment options, further enhancing BillionToOne's market position in the molecular diagnostics field.
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- Conference Participation: BillionToOne will participate in the 44th Annual J.P. Morgan Healthcare Conference on January 12, 2026, from 9:45 AM to 10:25 AM PT, showcasing its innovations in molecular diagnostics.
- Technological Advantage: The company’s patented Quantitative Counting Templates™ (QCT™) molecular counting platform can accurately count DNA molecules at the single-molecule level, enhancing the accuracy and accessibility of molecular diagnostics.
- Investor Relations: A live and archived webcast will be available during the conference, allowing investors to access information through the company’s “Events & Presentations” page, thereby improving investor engagement and transparency.
- Market Positioning: As an emerging molecular diagnostics company, BillionToOne aims to provide powerful and accurate tests to meet the growing market demand, thereby enhancing its influence in the healthcare industry.
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