Ascendis Pharma Added to Russell Indexes
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1 hour ago
0mins
Source: seekingalpha
- Inclusion in Russell Indexes: Ascendis Pharma (ASND) announced on Friday that it will be added to the Russell 3000, Russell 1000, Russell 2500, and Russell Midcap indexes as part of the 2026 Russell U.S. Indexes annual reconstitution, effective after the close of trading on June 26, which is expected to enhance its market visibility and liquidity.
- Automatic Style Index Inclusion: The inclusion in the Russell 1000, Russell 2500, and Russell Midcap indexes will also result in automatic inclusion in the corresponding growth and value style indexes, potentially attracting more institutional investors and driving stock price appreciation.
- Market Reaction Expectations: This inclusion is likely to trigger positive reactions from investors, particularly among index funds and ETFs that follow passive investment strategies, which is expected to increase demand for Ascendis Pharma shares and enhance its market performance.
- Long-Term Growth Potential: With a unique product portfolio in the endocrine space and ongoing clinical data supporting its growth potential, Ascendis Pharma is poised to achieve higher revenues and profitability as market attention increases.
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Analyst Views on ASND
Wall Street analysts forecast ASND stock price to rise
13 Analyst Rating
13 Buy
0 Hold
0 Sell
Strong Buy
Current: 261.580
Low
240.00
Averages
277.08
High
342.00
Current: 261.580
Low
240.00
Averages
277.08
High
342.00
About ASND
Ascendis Pharma A/S is a Denmark‑based biopharmaceutical company operating within the life sciences and biotechnology sector. The Company scope of activity includes discovery, development, and commercialization of innovative therapies for rare diseases and serious chronic conditions with significant unmet medical needs where a clinically validated parent drug or pathway is suitable to company technologies. Ascendis Pharma A/S focuses on the endocrinology area and has a pipeline of three independent rare disease product candidates, such as Growth Hormone Deficiency (GHD), Hypoparathyroidism and Achondroplasia. The second therapeutic area is oncology, where the company focuses immunotherapy to targeted therapies.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Ascendis Pharma Added to Russell Indexes
- Inclusion in Russell Indexes: Ascendis Pharma A/S has been added to the Russell 3000®, Russell 1000®, Russell 2500®, and Russell Midcap® indexes, marking an increase in the company's market recognition and is expected to attract more investor attention.
- Market Coverage Expansion: The Russell 3000® index tracks the largest 3,000 U.S. stocks, representing approximately 98% of investable U.S. equities, and Ascendis' inclusion will provide greater exposure within a broad investment portfolio.
- Benchmark Asset Impact: As of December 31, 2024, approximately $11.8 trillion in assets are benchmarked against Russell U.S. indexes, and Ascendis' inclusion may enhance its stock liquidity and market participation, thereby increasing the company's overall valuation.
- Strategic Implications: The inclusion not only boosts Ascendis' visibility among investors but may also facilitate future financing and collaboration opportunities, further driving the company's innovative development in the biopharmaceutical sector.
See More
Ascendis Pharma Added to Russell Indexes
- Inclusion in Russell Indexes: Ascendis Pharma (ASND) announced on Friday that it will be added to the Russell 3000, Russell 1000, Russell 2500, and Russell Midcap indexes as part of the 2026 Russell U.S. Indexes annual reconstitution, effective after the close of trading on June 26, which is expected to enhance its market visibility and liquidity.
- Automatic Style Index Inclusion: The inclusion in the Russell 1000, Russell 2500, and Russell Midcap indexes will also result in automatic inclusion in the corresponding growth and value style indexes, potentially attracting more institutional investors and driving stock price appreciation.
- Market Reaction Expectations: This inclusion is likely to trigger positive reactions from investors, particularly among index funds and ETFs that follow passive investment strategies, which is expected to increase demand for Ascendis Pharma shares and enhance its market performance.
- Long-Term Growth Potential: With a unique product portfolio in the endocrine space and ongoing clinical data supporting its growth potential, Ascendis Pharma is poised to achieve higher revenues and profitability as market attention increases.
See More
Ascendis Pharma Reports Three-Year Data on TransCon PTH Efficacy
- Sustained Long-term Efficacy: In the three-and-a-half-year PaTHway trial, TransCon PTH demonstrated an 86% response rate for the multi-component endpoint, successfully replicating endogenous parathyroid hormone actions and significantly improving patients' quality of life.
- Independence from Conventional Therapy: The trial showed that 100% of patients achieved independence from active vitamin D, and 96% maintained calcium intake below 600 mg/day, indicating TransCon PTH's effective replacement of traditional therapies.
- Improved Kidney Function: At Week 182, the mean estimated glomerular filtration rate (eGFR) reached 80.2 mL/min/1.73 m², reflecting an increase of 11.0 mL/min/1.73 m² from baseline, showcasing TransCon PTH's positive impact on renal function.
- Good Safety Profile: Throughout the trial, TransCon PTH was well-tolerated with no new safety signals identified, and all adverse events were mild or moderate, ensuring patient safety during treatment.
See More
Ascendis Pharma Reports Five-Year Data on TransCon PTH for Hypoparathyroidism
- Sustained Efficacy: Ascendis Pharma's TransCon PTH demonstrated sustained efficacy in the five-year Phase 2 trial, with 82% of patients achieving normal serum calcium levels by Week 266 without active vitamin D, indicating its potential as a new standard of care for hypoparathyroidism.
- Kidney Function Improvement: The trial showed a sustained increase in mean eGFR from baseline, reflecting the therapy's effectiveness in improving calcium levels while countering age-related kidney function decline, thereby enhancing patients' quality of life.
- Stable Bone Density: Bone mineral density scores were corrected early and remained stable over five years, highlighting TransCon PTH's long-term benefits for bone health and reinforcing its position as a new standard treatment for chronic hypoparathyroidism.
- Good Safety Profile: The therapy was generally well tolerated with no new safety signals identified; most adverse events were mild or moderate, and no patients discontinued treatment, demonstrating the safety and efficacy of TransCon PTH.
See More
Ascendis Pharma Reports Sustained Efficacy of Yorvipath Over Five Years
- Sustained Efficacy: Ascendis Pharma's adult hypoparathyroidism treatment Yorvipath (palopegteriparatide) demonstrated sustained efficacy in a five-year phase 2 trial, with 82% of patients achieving serum calcium levels within the normal range at week 266, indicating the treatment's effectiveness in improving patient health.
- Multi-System Impact: The hormone replacement therapy showed a balanced and beneficial impact on key target organ systems—kidneys, small intestine, CNS, and bones—evidenced by normalized and stable urine calcium, serum calcium, quality of life, and bone mineral density, highlighting its therapeutic potential across multiple dimensions.
- Trial Design: The PaTH Forward trial enrolled 59 participants, who underwent a four-week randomized, double-blind, placebo-controlled period followed by a 262-week open-label extension, with only 3 patients not completing the five-year study, demonstrating good tolerability and engagement.
- Market Outlook: As Ascendis Pharma enters a growth phase, its potential in the rare endocrine drug market is widely recognized, which is expected to enhance its future market performance and investment appeal.
See More
Ascendis Pharma to Present New Data at ENDO 2026
- Clinical Data Sharing: Ascendis Pharma will present the latest clinical trial data on hypoparathyroidism, achondroplasia, and pediatric growth hormone deficiency through two oral presentations and three posters at the 2026 ENDO meeting, showcasing the potential of its innovative therapies.
- Key Research Findings: At the conference, Ascendis will highlight the long-term safety and efficacy of TransCon PTH, based on results from multiple clinical trials, emphasizing its application prospects in treating patients with hypoparathyroidism.
- Advancements in Achondroplasia Treatment: Ascendis will also present 52-week results of Navepegritide combined with Lonapegsomatropin for treating children with achondroplasia, further validating its potential to improve patient growth and quality of life.
- Global Impact: This presentation not only enhances Ascendis' leadership position in rare endocrine diseases but may also attract more investor attention to its innovative technology platform, driving future business growth.
See More
Ascendis Pharma Added to Russell Indexes
- Inclusion in Russell Indexes: Ascendis Pharma A/S has been added to the Russell 3000®, Russell 1000®, Russell 2500®, and Russell Midcap® indexes, marking an increase in the company's market recognition and is expected to attract more investor attention.
- Market Coverage Expansion: The Russell 3000® index tracks the largest 3,000 U.S. stocks, representing approximately 98% of investable U.S. equities, and Ascendis' inclusion will provide greater exposure within a broad investment portfolio.
- Benchmark Asset Impact: As of December 31, 2024, approximately $11.8 trillion in assets are benchmarked against Russell U.S. indexes, and Ascendis' inclusion may enhance its stock liquidity and market participation, thereby increasing the company's overall valuation.
- Strategic Implications: The inclusion not only boosts Ascendis' visibility among investors but may also facilitate future financing and collaboration opportunities, further driving the company's innovative development in the biopharmaceutical sector.
See More
Ascendis Pharma Added to Russell Indexes
- Inclusion in Russell Indexes: Ascendis Pharma (ASND) announced on Friday that it will be added to the Russell 3000, Russell 1000, Russell 2500, and Russell Midcap indexes as part of the 2026 Russell U.S. Indexes annual reconstitution, effective after the close of trading on June 26, which is expected to enhance its market visibility and liquidity.
- Automatic Style Index Inclusion: The inclusion in the Russell 1000, Russell 2500, and Russell Midcap indexes will also result in automatic inclusion in the corresponding growth and value style indexes, potentially attracting more institutional investors and driving stock price appreciation.
- Market Reaction Expectations: This inclusion is likely to trigger positive reactions from investors, particularly among index funds and ETFs that follow passive investment strategies, which is expected to increase demand for Ascendis Pharma shares and enhance its market performance.
- Long-Term Growth Potential: With a unique product portfolio in the endocrine space and ongoing clinical data supporting its growth potential, Ascendis Pharma is poised to achieve higher revenues and profitability as market attention increases.
See More
Ascendis Pharma Reports Three-Year Data on TransCon PTH Efficacy
- Sustained Long-term Efficacy: In the three-and-a-half-year PaTHway trial, TransCon PTH demonstrated an 86% response rate for the multi-component endpoint, successfully replicating endogenous parathyroid hormone actions and significantly improving patients' quality of life.
- Independence from Conventional Therapy: The trial showed that 100% of patients achieved independence from active vitamin D, and 96% maintained calcium intake below 600 mg/day, indicating TransCon PTH's effective replacement of traditional therapies.
- Improved Kidney Function: At Week 182, the mean estimated glomerular filtration rate (eGFR) reached 80.2 mL/min/1.73 m², reflecting an increase of 11.0 mL/min/1.73 m² from baseline, showcasing TransCon PTH's positive impact on renal function.
- Good Safety Profile: Throughout the trial, TransCon PTH was well-tolerated with no new safety signals identified, and all adverse events were mild or moderate, ensuring patient safety during treatment.
See More
Ascendis Pharma Reports Five-Year Data on TransCon PTH for Hypoparathyroidism
- Sustained Efficacy: Ascendis Pharma's TransCon PTH demonstrated sustained efficacy in the five-year Phase 2 trial, with 82% of patients achieving normal serum calcium levels by Week 266 without active vitamin D, indicating its potential as a new standard of care for hypoparathyroidism.
- Kidney Function Improvement: The trial showed a sustained increase in mean eGFR from baseline, reflecting the therapy's effectiveness in improving calcium levels while countering age-related kidney function decline, thereby enhancing patients' quality of life.
- Stable Bone Density: Bone mineral density scores were corrected early and remained stable over five years, highlighting TransCon PTH's long-term benefits for bone health and reinforcing its position as a new standard treatment for chronic hypoparathyroidism.
- Good Safety Profile: The therapy was generally well tolerated with no new safety signals identified; most adverse events were mild or moderate, and no patients discontinued treatment, demonstrating the safety and efficacy of TransCon PTH.
See More
Ascendis Pharma Reports Sustained Efficacy of Yorvipath Over Five Years
- Sustained Efficacy: Ascendis Pharma's adult hypoparathyroidism treatment Yorvipath (palopegteriparatide) demonstrated sustained efficacy in a five-year phase 2 trial, with 82% of patients achieving serum calcium levels within the normal range at week 266, indicating the treatment's effectiveness in improving patient health.
- Multi-System Impact: The hormone replacement therapy showed a balanced and beneficial impact on key target organ systems—kidneys, small intestine, CNS, and bones—evidenced by normalized and stable urine calcium, serum calcium, quality of life, and bone mineral density, highlighting its therapeutic potential across multiple dimensions.
- Trial Design: The PaTH Forward trial enrolled 59 participants, who underwent a four-week randomized, double-blind, placebo-controlled period followed by a 262-week open-label extension, with only 3 patients not completing the five-year study, demonstrating good tolerability and engagement.
- Market Outlook: As Ascendis Pharma enters a growth phase, its potential in the rare endocrine drug market is widely recognized, which is expected to enhance its future market performance and investment appeal.
See More
Ascendis Pharma to Present New Data at ENDO 2026
- Clinical Data Sharing: Ascendis Pharma will present the latest clinical trial data on hypoparathyroidism, achondroplasia, and pediatric growth hormone deficiency through two oral presentations and three posters at the 2026 ENDO meeting, showcasing the potential of its innovative therapies.
- Key Research Findings: At the conference, Ascendis will highlight the long-term safety and efficacy of TransCon PTH, based on results from multiple clinical trials, emphasizing its application prospects in treating patients with hypoparathyroidism.
- Advancements in Achondroplasia Treatment: Ascendis will also present 52-week results of Navepegritide combined with Lonapegsomatropin for treating children with achondroplasia, further validating its potential to improve patient growth and quality of life.
- Global Impact: This presentation not only enhances Ascendis' leadership position in rare endocrine diseases but may also attract more investor attention to its innovative technology platform, driving future business growth.
See More
