Arbutus Reacquires Greater China Rights to Imdusiran and Announces Scientific Advisory Board with Late-Stage Clinical Focus
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jun 25 2025
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Source: Newsfilter
Strategic Partnership Conclusion: Arbutus Biopharma has mutually agreed with Qilu Pharmaceutical to end their strategic partnership for the development and commercialization of imdusiran in Greater China, allowing Arbutus to regain global rights to the compound.
New Scientific Advisory Board: Arbutus has established a new Scientific Advisory Board consisting of prominent experts in hepatitis B treatment to guide its clinical pipeline, while reporting successful outcomes from Phase 2a trials of imdusiran, which has shown functional cure in eight patients.
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Analyst Views on ABUS
About ABUS
Arbutus Biopharma Corporation is a clinical-stage biopharmaceutical company focused on infectious disease. The Company is developing imdusiran (AB-729), its proprietary, conjugated GalNAc, subcutaneously delivered RNAi therapeutic, and AB-101, its proprietary oral PD-L1 inhibitor, for the treatment of chronic hepatitis B (cHBV). Its HBV product pipeline includes Imdusiran and AB-101. Its pipeline includes two product candidates that target various steps in the HBV viral lifecycle and consists of various programs: RNAi therapeutic (imdusiran, AB-729) and Oral PD-L1 Inhibitor (AB-101). RNAi therapeutics utilize a natural pathway within cells to silence genes by eliminating the disease-causing proteins that they code for. PD-L1 inhibitors complement its pipeline of agents and could potentially be a part of a combination therapy for the treatment of HBV by reawakening the immune system.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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