Actinium Pharmaceuticals' ATNM-400 Demonstrates Enhanced Anti-Tumor Efficacy
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Oct 27 2025
0mins
ATNM-400 Preclinical Data: Actinium Pharmaceuticals presented the first preclinical data for ATNM-400 in non-small cell lung cancer (NSCLC), showing superior efficacy with 3-5 times greater tumor growth inhibition compared to standard therapies.
Synergistic Activity: The combination of ATNM-400 with osimertinib resulted in complete tumor regression in all tested animals, indicating a strong synergistic effect that outperformed either treatment alone.
Improved Survival Rates: Data showed that combining external beam radiotherapy with osimertinib improved progression-free survival compared to osimertinib alone, supporting the clinical rationale for this combination therapy.
Targeted Therapy Potential: ATNM-400 demonstrated significant tumor growth inhibition in human lung cancer models, suggesting its potential as a promising treatment option for EGFR-mutant NSCLC.
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Analyst Views on AZN
Wall Street analysts forecast AZN stock price to rise
14 Analyst Rating
13 Buy
0 Hold
1 Sell
Strong Buy
Current: 208.620
Low
157.61
Averages
213.64
High
252.18
Current: 208.620
Low
157.61
Averages
213.64
High
252.18
About AZN
AstraZeneca PLC is a United Kingdom-based science-led biopharmaceutical company. The Company focuses on the discovery, development, and commercialization of prescription medicines. The Company operates across therapy areas, including Oncology; Cardiovascular, Renal and Metabolism (CVRM); Respiratory and Immunology (R&I); Vaccines and Immune Therapies (V&I), and Rare Disease. In the Oncology area, its key products include Tagrisso, Imfinzi, Calquence, Lynparza, and Enhertu. The key products of CVRM area include Farxiga/Forxiga, Brilinta/Brilique, Crestor, and Lokelma. In the R&I area, the key products are Symbicort, Fasenra, Breztri/Trixeo, and Tezspire. In the V&I Therapies area, the products are Beyfortus and FluMist. The products in the Rare Disease area are Ultomiris, Soliris, Strensiq, and Koselugo. It has about 191 projects in its development pipeline, including 19 new molecular entities (NMEs) in the late-stage pipeline. The Company distributes its products in over 125 countries.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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