AC IMMUNE SA TO RECEIVE CHF 10 MILLION UPFRONT PAYMENT AND PHASE 1 MILESTONE PAYMENT UNDER AMENDMENT

Written by Emily J. Thompson, Senior Investment Analyst

Source: moomoo

Updated: 2 days ago

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Source: moomoo

Amendment Overview: The article discusses a recent amendment related to a financial agreement or contract.
Payment Details: It highlights a front payment of 10 million and mentions a milestone payment as part of the agreement.

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About ACIU

AC Immune SA is a Switzerland-based clinical-stage biopharmaceutical company. The Company focuses on precision medicine for neurodegenerative diseases. It designs, discovers and develops therapeutic, as well as diagnostic products for prevention, diagnosis and treatment of diseases caused by misfolding proteins. Its SupraAntigen and Morphomer technology platforms to create antibodies, small molecules and vaccines designed to address a broad range of neurodegenerative indications, such as Alzheimer's disease (AD). The Company's pipeline includes nine therapeutic product candidates with five in clinical trials, and three diagnostic candidates. Its lead product candidate is Crenezumab, a humanized and monoclonal anti-Abeta antibody for Alzheimer’s disease. It has collaborations with pharmaceutical companies, including Roche/Genentech, Eli Lilly, Biogen, Janssen Pharmaceuticals, Nestle Institute of Health Sciences, Life Molecular Imaging (formerly Piramal Imaging) and Essex Bio-Technology.

About the author

Emily J. Thompson

Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.

AC Immune Revises Collaboration Agreement with Eli Lilly

1 day agoFool

Collaboration Agreement Revision: AC Immune has amended its collaboration agreement with Eli Lilly, which will pay 10 million Swiss francs ($12.5 million) as an upfront payment, demonstrating confidence in AC Immune's development of treatments for Alzheimer's and other neurodegenerative diseases.
Significant Potential Revenue: If AC Immune successfully develops a drug and meets clinical, regulatory, and commercial milestones, total payments could exceed 1.7 billion Swiss francs ($2.1 billion), significantly enhancing the company's financial position and market standing.
Clinical Trial Progress: CEO Andrea Pfeifer indicated that the company expects to initiate Investigational New Drug (IND)-enabling studies imminently, marking a new stage in its development that could accelerate the path to market for new therapies.
Positive Market Reaction: Following this favorable collaboration news, AC Immune's stock surged nearly 15% on Tuesday, reflecting investor optimism about the company's future prospects and increasing its visibility in the biotech sector.

AC Immune Amends Collaboration Agreement with Eli Lilly

1 day agoseekingalpha

Agreement Amendment: AC Immune has amended its 2018 collaboration agreement with Eli Lilly, continuing to cover R&D efforts for the new class of neurology therapies, Morphomer Tau, indicating ongoing partnership in neurodegenerative diseases like Alzheimer's.
Increased Funding: The amendment allows AC Immune to receive an upfront payment of CHF 10 million and a milestone payment upon the start of Phase 1 dosing, providing crucial financial support for its R&D efforts and enhancing its financial stability.
R&D Timeline: AC Immune plans to initiate investigational new drug (IND)-enabling studies in H1 2026, establishing a timeline that will bolster the company's competitive position in the neurodegenerative disease treatment market.
Positive Market Reaction: Following the agreement amendment, AC Immune's stock price rose, reflecting investor optimism regarding the company's future R&D potential, which may attract more investor interest in its innovative capabilities within the biotech sector.

AC Immune Amends Tau Collaboration Agreement with Lilly

2 days agoNewsfilter

Collaboration Agreement Amendment: AC Immune has amended its 2018 collaboration agreement with Eli Lilly to develop Tau aggregation inhibitors for Alzheimer's and other neurodegenerative diseases, reflecting growing excitement for intracellular Tau targeting.
Financial Support: Under the amended agreement, AC Immune will receive a CHF 10 million upfront payment and subsequent milestone payments upon Phase 1 dosing, along with over CHF 1.7 billion in potential development and commercial milestones, showcasing the company's strong funding capabilities in this area.
Clinical Research Plans: Investigational New Drug (IND)-enabling studies are expected to commence in H1 2026, marking significant progress in the development of small molecule therapeutics for early intervention and long-term prevention of neurodegenerative diseases.
Technology Platform Advantage: AC Immune's Morphomer platform has demonstrated robust preclinical data indicating its small molecules can effectively inhibit Tau protein aggregation, further solidifying the company's leadership in precision prevention of neurodegenerative diseases.

AC IMMUNE SA - QUALIFIES FOR OVER CHF1.7 BILLION IN MILESTONES AND TIERED ROYALTIES

2 days agomoomoo

Eligibility for Overchf: The article discusses the eligibility criteria for a program or initiative referred to as "Overchf."
Financial Milestones: It highlights a significant financial milestone of 1.7 billion, indicating a substantial achievement or target within the context of the program.