Teva Pharmaceutical reaches 52-week high amid Eylea biosimilar agreement
Teva Pharmaceutical Industries Ltd experienced a price increase of 3.01%, reaching a 52-week high. This movement comes amid broader market strength, with the Nasdaq-100 up 0.35% and the S&P 500 up 0.65%.
The surge is attributed to the settlement agreement between Alvotech and Teva, allowing for the U.S. launch of their biosimilar AVT06 in Q4 2026. This strategic partnership not only enhances Alvotech's market entry strategy but also solidifies Teva's position in the competitive biopharmaceutical landscape, boosting investor confidence.
This collaboration is expected to significantly enhance Teva's market share and brand influence, particularly as Alvotech has received marketing approval for AVT06 in multiple international markets, laying a solid foundation for future revenue growth.
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- Earnings Beat: Teva Pharmaceutical's fiscal Q4 2025 revenue reached $4.71 billion, reflecting an 11.4% year-over-year growth that exceeded Wall Street estimates by $385.8 million, showcasing strong performance from innovative brands like AUSTEDO, AJOVY, and UZEDY, which collectively surpassed $1 billion in revenue for the first time.
- Analyst Rating Upgrade: Goldman Sachs analyst Matthew Dellatorre reiterated a Buy rating on Teva, raising the price target from $36 to $45, indicating strong market confidence in the company's growth potential, while Trust Financial also increased its target from $36 to $38, reflecting a positive outlook among analysts.
- Stock Price Surge: Teva's stock has surged over 105% in the past year, driven by the resolution of key challenges and improved execution across its portfolio; despite trading above historical multiples, the valuation remains attractive due to enhanced business profile, revenue growth, and debt reduction.
- Future Growth Potential: Analysts at Truist highlight that Teva is in the early stages of expansion, with an FDA decision on Olanzapine LAI potentially yielding a $3 billion peak sales opportunity, further boosting investor confidence in the company's future prospects.
- Long-Term Efficacy: The RELIEVE UCCD LTE study demonstrated that duvakitug maintained robust efficacy over 44 weeks in ulcerative colitis (UC) and Crohn's disease (CD) patients, with 58% of the 900mg group achieving the primary endpoint of clinical remission, highlighting its potential in IBD treatment.
- Good Safety Profile: The safety of duvakitug was consistent with prior induction studies, with the most common adverse events being upper respiratory tract infections and nasopharyngitis, each occurring in over 5% of patients, indicating good tolerability of the drug.
- Clinical Research Progress: The study enrolled 130 patients who entered a 44-week maintenance period, where they were re-randomized to receive either 450mg or 900mg of duvakitug, further validating its efficacy and safety in treating IBD.
- Future Development Outlook: Teva and Sanofi are advancing duvakitug into phase 3 clinical trials, expected to provide new treatment options for IBD patients, reinforcing duvakitug's position as a leading TL1A-targeted therapy.
- Patent Dispute Loss: Corcept Therapeutics' shares plummeted over 20% following a federal appeals court ruling against the company in a patent dispute with Israeli drugmaker Teva, highlighting the company's vulnerability in market competition.
- FDA Approval of Generic: Teva received FDA approval in August 2020 to market a generic version of Korlym, a once-daily oral medication for Cushing's syndrome, which intensifies the market pressure on Corcept.
- Court Ruling Impact: The U.S. Court of Appeals upheld the New Jersey District Court's ruling that Teva did not infringe Corcept's U.S. patents, indicating significant challenges for Corcept in protecting its intellectual property.
- Market Reaction: The sharp decline in Corcept's stock price reflects investor concerns about the company's future profitability, particularly in light of generic competition and setbacks in patent protection.
- Investment Strategy Shift: David Einhorn invested tens of millions in Q4 2025 to increase stakes in Graphic Packaging and Capri Holdings by over 70%, reflecting his concerns about AI-driven market overvaluation and indicating a strategic pivot away from big tech.
- Stock Performance Volatility: Despite Graphic Packaging's shares dropping about 23% in Q4 2025 and over 44% for the year, Wall Street analysts remain optimistic, with an average price target suggesting more than 35% upside, indicating expectations for a rebound in the stock.
- Healthcare Investments: Einhorn more than doubled his position in Acadia Healthcare to over $58 million, despite a 43% plunge in Q4; however, analysts maintain a buy rating with a price target suggesting over 16% upside in the next 12 months, reflecting confidence in its recovery.
- Cautious on Tech Stocks: While expressing concerns about tech valuations, Einhorn established a $35 million stake in Global Payments, which fell 31% in 2025 but rebounded nearly 5% in 2026, with analysts' price targets implying over 25% upside, suggesting market optimism for its future performance.
- Significant Clinical Efficacy: The RELIEVE UCCD study by Teva and Sanofi revealed that 58% (900mg) and 47% (450mg) of ulcerative colitis patients achieved clinical remission, while 55% (900mg) and 41% (450mg) of Crohn's disease patients reached endoscopic response, indicating duvakitug's potential to transform IBD treatment.
- Good Tolerability: Among 130 patients, both doses of duvakitug demonstrated good tolerability with no severe adverse reactions reported during the 58-week treatment, enhancing the drug's market prospects and patient acceptance.
- Market Performance Analysis: Teva's stock is currently priced at $34.94, trading 6.3% below its 20-day simple moving average, indicating some short-term pressure; however, it has surged 105.07% over the past 12 months, nearing its 52-week high, reflecting market confidence in its long-term potential.
- Optimistic Analyst Ratings: Teva's stock carries a Buy rating with an average price target of $31.75, with Goldman Sachs raising its target to $45, and Barclays and Scotiabank adjusting theirs to $38 and $40 respectively, showcasing analysts' confidence in its future growth.
- Significant Clinical Outcomes: Teva and Sanofi's TL1A antibody duvakitug demonstrated sustained clinical and endoscopic benefits through 44 weeks in ulcerative colitis and Crohn's disease patients, reinforcing efficacy seen in the RELIEVE UCCD phase 2b study.
- Robust Study Design: The RELIEVE UCCD LTE is a double-blind randomized study focused on evaluating the long-term efficacy, safety, and tolerability of duvakitug in these common inflammatory bowel diseases, ensuring the reliability and scientific rigor of the data.
- Positive Market Reaction: Teva's shares rose 2.7% in premarket trading, while Sanofi gained 0.46%, indicating a favorable investor response to the study results, which could enhance future market performance.
- Strategic Implications: The study results not only solidify duvakitug's market potential but may also provide new growth momentum for Teva and Sanofi in the inflammatory bowel disease sector, further advancing their positioning in the biopharmaceutical market.









