Psyence Biomedical Surges on U.S. Executive Order for Ibogaine Research
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jul 31 2025
0mins
Should l Buy PBM?
Psyence Biomedical Ltd. (PBM) shares surged by 70.02%, reaching a 20-day high, following positive developments regarding U.S. regulatory support for ibogaine research.
The company welcomed the U.S. administration's preparation of an executive order to evaluate ibogaine's safety and therapeutic potential, which may advance its clinical research in PTSD and addiction. CEO Jody Aufrichtig emphasized the importance of structured, evidence-based research to clarify ibogaine's efficacy, enhancing patient safety and the company's competitive position. Additionally, Psyence's strategic investment in PsyLabs positions it favorably in GMP-compliant manufacturing of ibogaine, supporting global clinical research and future therapeutic development.
This surge in stock price reflects strong market interest in psychedelic research and the potential for increased federal funding for studies on PTSD and traumatic brain injuries. The positive sentiment around PBM stock indicates a robust investor outlook for the company's future in the biopharmaceutical sector.
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Analyst Views on PBM
About PBM
Psyence Biomedical Ltd is a multi-asset, vertically integrated biopharmaceutical company specializing in psychedelic-based therapeutics. The Company is focused on developing nature-derived (non-synthetic) psilocybin-based psychedelic medicine. It is dedicated to addressing unmet mental health needs, particularly in palliative care. Its ongoing Phase IIb psilocybin clinical trial in Australia focuses on adjustment disorder in patients diagnosed with cancer.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Trump Accelerates Psychedelic Research, PBM Stock Soars
- Policy-Driven Funding: Trump signed an executive order directing the FDA to expedite reviews of psychedelic medicines while committing $50 million for clinical research, providing robust policy support for the legalization and application of psychedelics.
- Stock Surge Performance: Following Trump's announcement, Psyence Biomedical (PBM) shares surged over 111% in premarket trading on Monday and achieved a remarkable 185% increase last week, indicating strong market performance and renewed investor confidence in the psychedelic sector.
- Production Capacity Enhancement: Psyence has established a GMP-compliant platform for producing medical-grade ibogaine, ensuring its application in clinical research and drug development, and has sourced high-purity ibogaine hydrochloride from Africa, showcasing its competitive edge in the global market.
- Market Sentiment Extremely Bullish: Retail sentiment for PBM on Stocktwits has remained extremely bullish, with message volumes surging 15,100% over the past month, reflecting strong market expectations and confidence in PBM's future, particularly regarding the potential demand for psychedelic therapies.
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- Strait of Hormuz Tensions: Iran's announcement to keep the critical shipping route restricted, coupled with President Trump's confirmation of seizing an Iranian cargo ship, has reignited market focus on oil price volatility, prompting renewed interest in oil-linked stocks like BATL and EONR.
- Psychedelic Stocks Surge: Following President Trump's executive order to expedite psychedelic drug approvals, stocks like Psyence Biomedical (PBM), Definium Therapeutics (DFTX), and Compass Pathways (CMPS) are gaining retail investor attention, reflecting a growing market interest in mental health treatments.
- Tesla's Positive Outlook: Tesla is on track for its first positive month this year, with Elon Musk downplaying competitive fears from China's BYD, emphasizing that execution, rather than competition, is the key challenge for the EV maker, showcasing the company's confidence in its future performance.
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Trump Administration to Examine Safety of Psychedelic Drug for PTSD
- Psychedelic Research Advancement: The Trump administration is drafting an executive order indicating a willingness to further investigate the safety and efficacy of ibogaine, a psychedelic used for treating PTSD, which is expected to accelerate clinical research in this area.
- Positive Market Reaction: Following the announcement, stocks of companies like Clearmind Medicine (CMND), Atai Beckley (ATAI), and Cybin (HELP) rose, reflecting market optimism regarding the potential applications of psychedelics in mental health treatment.
- Strait of Hormuz Passage Statement: Iran's Foreign Minister declared that commercial vessels can fully pass through the Strait of Hormuz during the ceasefire in Lebanon, while Trump confirmed normal passage but maintained a naval blockade against Iran, highlighting the complexities of geopolitical tensions in the region.
- AI Model Utilization: The U.S. government is preparing to make Anthropic PBC's AI model Mythos available to major federal agencies despite cybersecurity risks, indicating a balancing act between promoting technological innovation and ensuring data security.
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- Strong Performance in Health Care: The NYSE Health Care Index rose 1.4% late Friday afternoon, indicating a rebound in investor confidence towards the healthcare sector, likely driven by an overall improvement in market sentiment.
- Signs of Market Recovery: The rise in healthcare stocks suggests that investors may be reassessing the growth potential of the healthcare industry while seeking safe-haven assets amid increasing economic uncertainty.
- Increased Investor Attention: The uptick in healthcare stocks could attract more investor interest, particularly as the healthcare sector is viewed as a relatively stable investment choice in the current economic climate, potentially leading to increased capital inflows.
- Optimistic Industry Outlook: The upward trend in the healthcare sector may reflect market optimism regarding future medical innovations and policy support, further driving stock price increases for related companies.
See More
Trump to Sign Executive Order on Psychedelic Research
- Stock Surge: Psyence Biomedical Ltd. (PBM) shares closed over 100% higher on Thursday and continued to rally by 42% on Friday, indicating the company is on track for its best trading week in over two years, reflecting strong market interest in psychedelic research.
- Executive Order Impact: The Trump administration is expected to sign an executive order this week aimed at opening federal funding for research on PTSD and traumatic brain injuries, although ibogaine will remain classified as a Schedule I drug, indicating a cautious governmental approach to psychedelic research.
- Strategic Investment: Psyence highlighted its strategic investment in Psylabs, a biopharmaceutical company in Southern Africa specializing in the cultivation and extraction of nature-derived psychedelic active pharmaceutical ingredients, showcasing the company's long-term commitment to the psychedelic sector.
- Market Sentiment: Retail sentiment around PBM stock has remained in the 'extremely bullish' territory over the past 24 hours, with message volume jumping from 'high' to 'extremely high', indicating strong investor interest in the upcoming research opportunities.
See More
Psyence Supports U.S. Regulated Research on Ibogaine
- Regulatory Research Support: Psyence Biomedical Ltd. expresses support for emerging U.S. regulatory efforts aimed at advancing research into Ibogaine, a naturally occurring psychedelic compound being studied for PTSD and addiction treatment.
- Drug Regulation Dynamics: Although Ibogaine remains a Schedule I substance in the U.S., with patients often seeking unregulated access abroad, the anticipated federal action indicates a growing recognition of the need for controlled evidence-based research, particularly for treatment-resistant conditions.
- Safety and Accessibility: CEO Jody Aufrichtig emphasizes that as global interest in Ibogaine accelerates, structured research and regulated development pathways are essential for improving patient safety and long-term access to these therapies.
- Business Development and Market Performance: PsyLabs, the company's Active Pharmaceutical Ingredient development arm, is federally licensed to cultivate, extract, and export psychedelic compounds, and the company recently executed a 16-for-100 reverse stock split, with current trading at $8.27, reflecting a 40.72% increase.
See More
Trump Accelerates Psychedelic Research, PBM Stock Soars
- Policy-Driven Funding: Trump signed an executive order directing the FDA to expedite reviews of psychedelic medicines while committing $50 million for clinical research, providing robust policy support for the legalization and application of psychedelics.
- Stock Surge Performance: Following Trump's announcement, Psyence Biomedical (PBM) shares surged over 111% in premarket trading on Monday and achieved a remarkable 185% increase last week, indicating strong market performance and renewed investor confidence in the psychedelic sector.
- Production Capacity Enhancement: Psyence has established a GMP-compliant platform for producing medical-grade ibogaine, ensuring its application in clinical research and drug development, and has sourced high-purity ibogaine hydrochloride from Africa, showcasing its competitive edge in the global market.
- Market Sentiment Extremely Bullish: Retail sentiment for PBM on Stocktwits has remained extremely bullish, with message volumes surging 15,100% over the past month, reflecting strong market expectations and confidence in PBM's future, particularly regarding the potential demand for psychedelic therapies.
See More
U.S. Stock Futures Retreat Amid Renewed Geopolitical Tensions
- Futures Pullback: U.S. stock futures retreated early Monday after last week's record highs, with S&P 500 and Nasdaq futures down 0.6% and 0.7% respectively, indicating rising investor concerns over geopolitical risks.
- Strait of Hormuz Tensions: Iran's announcement to keep the critical shipping route restricted, coupled with President Trump's confirmation of seizing an Iranian cargo ship, has reignited market focus on oil price volatility, prompting renewed interest in oil-linked stocks like BATL and EONR.
- Psychedelic Stocks Surge: Following President Trump's executive order to expedite psychedelic drug approvals, stocks like Psyence Biomedical (PBM), Definium Therapeutics (DFTX), and Compass Pathways (CMPS) are gaining retail investor attention, reflecting a growing market interest in mental health treatments.
- Tesla's Positive Outlook: Tesla is on track for its first positive month this year, with Elon Musk downplaying competitive fears from China's BYD, emphasizing that execution, rather than competition, is the key challenge for the EV maker, showcasing the company's confidence in its future performance.
See More
Trump Administration to Examine Safety of Psychedelic Drug for PTSD
- Psychedelic Research Advancement: The Trump administration is drafting an executive order indicating a willingness to further investigate the safety and efficacy of ibogaine, a psychedelic used for treating PTSD, which is expected to accelerate clinical research in this area.
- Positive Market Reaction: Following the announcement, stocks of companies like Clearmind Medicine (CMND), Atai Beckley (ATAI), and Cybin (HELP) rose, reflecting market optimism regarding the potential applications of psychedelics in mental health treatment.
- Strait of Hormuz Passage Statement: Iran's Foreign Minister declared that commercial vessels can fully pass through the Strait of Hormuz during the ceasefire in Lebanon, while Trump confirmed normal passage but maintained a naval blockade against Iran, highlighting the complexities of geopolitical tensions in the region.
- AI Model Utilization: The U.S. government is preparing to make Anthropic PBC's AI model Mythos available to major federal agencies despite cybersecurity risks, indicating a balancing act between promoting technological innovation and ensuring data security.
See More
Health Care Stocks Rise 1.4% on NYSE
- Strong Performance in Health Care: The NYSE Health Care Index rose 1.4% late Friday afternoon, indicating a rebound in investor confidence towards the healthcare sector, likely driven by an overall improvement in market sentiment.
- Signs of Market Recovery: The rise in healthcare stocks suggests that investors may be reassessing the growth potential of the healthcare industry while seeking safe-haven assets amid increasing economic uncertainty.
- Increased Investor Attention: The uptick in healthcare stocks could attract more investor interest, particularly as the healthcare sector is viewed as a relatively stable investment choice in the current economic climate, potentially leading to increased capital inflows.
- Optimistic Industry Outlook: The upward trend in the healthcare sector may reflect market optimism regarding future medical innovations and policy support, further driving stock price increases for related companies.
See More
Trump to Sign Executive Order on Psychedelic Research
- Stock Surge: Psyence Biomedical Ltd. (PBM) shares closed over 100% higher on Thursday and continued to rally by 42% on Friday, indicating the company is on track for its best trading week in over two years, reflecting strong market interest in psychedelic research.
- Executive Order Impact: The Trump administration is expected to sign an executive order this week aimed at opening federal funding for research on PTSD and traumatic brain injuries, although ibogaine will remain classified as a Schedule I drug, indicating a cautious governmental approach to psychedelic research.
- Strategic Investment: Psyence highlighted its strategic investment in Psylabs, a biopharmaceutical company in Southern Africa specializing in the cultivation and extraction of nature-derived psychedelic active pharmaceutical ingredients, showcasing the company's long-term commitment to the psychedelic sector.
- Market Sentiment: Retail sentiment around PBM stock has remained in the 'extremely bullish' territory over the past 24 hours, with message volume jumping from 'high' to 'extremely high', indicating strong investor interest in the upcoming research opportunities.
See More
Psyence Supports U.S. Regulated Research on Ibogaine
- Regulatory Research Support: Psyence Biomedical Ltd. expresses support for emerging U.S. regulatory efforts aimed at advancing research into Ibogaine, a naturally occurring psychedelic compound being studied for PTSD and addiction treatment.
- Drug Regulation Dynamics: Although Ibogaine remains a Schedule I substance in the U.S., with patients often seeking unregulated access abroad, the anticipated federal action indicates a growing recognition of the need for controlled evidence-based research, particularly for treatment-resistant conditions.
- Safety and Accessibility: CEO Jody Aufrichtig emphasizes that as global interest in Ibogaine accelerates, structured research and regulated development pathways are essential for improving patient safety and long-term access to these therapies.
- Business Development and Market Performance: PsyLabs, the company's Active Pharmaceutical Ingredient development arm, is federally licensed to cultivate, extract, and export psychedelic compounds, and the company recently executed a 16-for-100 reverse stock split, with current trading at $8.27, reflecting a 40.72% increase.
See More
