Eli Lilly's Gene Editing Drug Shows Significant Progress
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jun 03 2026
0mins
Source: Fool
- Weight Loss Market Growth: Eli Lilly's weight-loss drug Zepbound has become a best-seller, and the recently approved oral weight-loss pill Foundayo is also performing well, showcasing the company's strong competitive position in the rapidly growing weight-loss drug market.
- Gene Editing Potential: Eli Lilly's clinical trial results for VERVE-102 indicate that a one-time infusion can significantly lower LDL cholesterol with durable effects, potentially offering a revolutionary treatment option for high-risk cardiovascular patients and further solidifying its position in the gene editing space.
- Market Competition Landscape: While CRISPR Therapeutics' CTX310 also aims to reduce LDL and triglycerides, both target different patient populations and have distinct mechanisms, suggesting that the gene editing market could accommodate multiple winners, with Eli Lilly's entry posing a threat to smaller gene editing firms.
- Investment Choice Analysis: As an established pharmaceutical company, Eli Lilly offers stable revenue and profits, with its exploration in gene editing providing a relatively safe option for investors, whereas CRISPR Therapeutics presents a higher-risk, higher-reward investment opportunity suitable for those with a greater risk tolerance.
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Analyst Views on LLY
Wall Street analysts forecast LLY stock price to rise
20 Analyst Rating
18 Buy
2 Hold
0 Sell
Strong Buy
Current: 1112.000
Low
950.00
Averages
1192
High
1500
Current: 1112.000
Low
950.00
Averages
1192
High
1500
About LLY
Eli Lilly and Company is a medicine company, which discovers, develops, manufactures, and market products in a single business segment called human pharmaceutical products. The Company manufacture and distribute its products through facilities in the United States, including Puerto Rico, and in Europe and Asia. The Company’s products are sold in approximately 90 countries. Its Cardiometabolic Health products Basaglar; Humalog, Humalog Mix 75/25, Humalog U-100, Humalog U-200, Humalog Mix 50/50, insulin lispro, and others; Humulin, Humulin 70/30, and others; Jardiance; Mounjaro; Trulicity; Zepbound, and others. Its oncology products include Cyramza, Erbitux, Tyvyt, Verzenio, Retevmo, Jaypirca, and others. Its immunology products include Ebglyss, Olumiant, Omvoh, and Taltz. Its neuroscience products include Emgality and Kisunla. Its LillyDirect, a direct-to-patient digital health care platform, provides delivery of select Lilly medicines dispensed by third-party pharmacies to patients.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Massive Acquisition Scale: Eli Lilly has announced over $25 billion in acquisitions in 2026, covering areas such as sleep medicine, blood cancers, cell therapy, and vaccines, indicating a strategic diversification beyond metabolic medicine.
- New Oncology Platform: By acquiring Kelonia Therapeutics, Lilly deepens its position in oncology cell therapy, with an upfront payment of $3.3 billion and potential milestone payments of up to $7 billion, which could drive future growth.
- Expansion in Blood Cancer: The acquisition of Ajax Therapeutics will provide Lilly with a JAK2 inhibitor for bone marrow cancer, with a total deal value of up to $2.3 billion, enhancing its technological and data capabilities in blood cancer treatment.
- Breakthrough in Sleep Medicine: The $6.3 billion acquisition of Centessa Pharmaceuticals grants Lilly access to advanced clinical assets for treating narcolepsy, marking a significant advancement in sleep medicine and expected to substantially enhance the company's product portfolio.
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- Weight Loss Market Potential: Eli Lilly's weight loss drugs, Zepbound and oral GLP-1 medication Foundayo, are experiencing rapid sales growth, particularly after Foundayo's approval for chronic weight management, with 80% of prescriptions coming from new GLP-1 users, indicating significant market potential and likely enhancing the company's leadership in this sector.
- Pipeline Diversification Investment: Eli Lilly is investing billions through acquisitions and licensing agreements to diversify its product lineup, particularly in oncology and neuroscience, with the acquisition of Morphic Holdings' MORF-057 oral medication for inflammatory bowel diseases poised to capture a significant market share, thereby reducing reliance on diabetes and obesity drugs.
- Dividend Growth Appeal: Although Eli Lilly's dividend yield is around 0.6%, the company has achieved a remarkable 239% increase in dividends over the past decade, showcasing its potential for healthy dividend growth, which attracts income-seeking investors and enhances its investment appeal.
- Strengthening Market Leadership: Eli Lilly's strong position in the weight loss market, combined with robust pipeline investments and ongoing revenue and earnings growth, positions the company to continue leading the industry over the next decade, making it a focal point for investors.
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- Intensifying Market Competition: Novo Nordisk's Wegovy pill has quickly reached three million prescriptions, indicating consumer preference for oral medications, despite competition from Eli Lilly's new drug Foundayo, which appears less effective and faces a tougher market introduction.
- Transition Year Challenges: Novo Nordisk's stock has plummeted 70% from its 2024 highs, with the company warning of a difficult 2026 due to drug price reductions in the U.S. and generic competition in India, leading to a bearish sentiment among investors in the short term.
- Long-Term Growth Potential: Despite the uncertain short-term outlook, Novo Nordisk anticipates accelerated growth as demand for GLP-1 drugs increases, particularly with the rapid uptake of the Wegovy pill indicating market acceptance and potential for future expansion.
- Attractive Investment Opportunity: With a price-to-earnings ratio of 10x, significantly lower than Eli Lilly's 40x, and a 4.1% dividend yield, Novo Nordisk presents a compelling value proposition for income-focused investors looking for growth opportunities in the pharmaceutical sector.
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- Intensifying Market Competition: Novo Nordisk's Wegovy pill has quickly reached three million prescriptions, indicating strong demand in the weight-loss drug market, despite competition from Eli Lilly's more effective drugs, suggesting a growing preference for oral medications.
- Pricing Strategy Adjustment: Novo Nordisk has agreed to lower drug prices in the U.S. market and faces generic competition in India, a strategy aimed at addressing potential difficulties in 2026; despite a 70% stock price drop in the short term, long-term growth potential remains.
- Shift in Investor Focus: Although Wall Street's confidence in Novo Nordisk has waned, with concerns about its future, the company believes growth will accelerate as demand for GLP-1 drugs increases, indicating that the market may be underestimating its value and growth potential.
- Attracting Income Investors: With a price-to-earnings ratio of 10x, significantly lower than Eli Lilly's 40x, and a 4.1% dividend yield, Novo Nordisk appeals to income-focused investors, highlighting its long-term opportunities in the weight-loss drug market.
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- Drug Innovation: Novo Nordisk's Wegovy pill has quickly gained market traction, reaching 3 million prescriptions, indicating a strong consumer preference for oral medications, which could further enhance the company's market share in the GLP-1 space.
- Intensifying Competition: While Novo Nordisk leads in the GLP-1 drug market, competitor Eli Lilly has launched the oral drug Foundayo, which, despite being less effective, poses a threat to Novo Nordisk, particularly in terms of market education and consumer acceptance.
- Negative Market Reaction: Novo Nordisk's stock has fallen 70% from its 2024 highs, and although it faces short-term challenges, the company anticipates long-term growth potential as demand for GLP-1 drugs increases, especially with drug price reductions.
- Investment Opportunity Assessment: With a price-to-earnings ratio of 10x, significantly lower than Eli Lilly's 40x, and a 4.1% dividend yield, Novo Nordisk may attract income-focused investors, despite the market's pessimistic outlook on its short-term performance.
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- Massive Acquisition Scale: Eli Lilly has announced over $25 billion in biotech acquisitions in 2026 through approximately 10 deals, with seven completed in the last three months, reflecting its aggressive expansion strategy amid a windfall from obesity drugs.
- Cell Therapy Positioning: The $3.3 billion acquisition of Kelonia Therapeutics aims to strengthen Lilly's foothold in oncology cell therapy, with Kelonia's multiple myeloma candidate still in early clinical trials, yet its technology holds significant potential to enhance treatment efficiency.
- New Technology Acquisition: By acquiring CrossBridge Bio, Lilly gains access to a dual-payload antibody-drug conjugate platform, which, despite lacking clinical candidates, could open new avenues for cancer drug development in the future.
- Strategic Investment: Lilly's $6.3 billion acquisition of Centessa Pharmaceuticals secures a clinically advanced asset for treating narcolepsy, expanding its product line and potentially providing new revenue streams, thereby enhancing its competitiveness outside metabolic medicine.
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