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QURE Should I Buy

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Intellectia

Should You Buy Uniqure NV (QURE) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
27.100
1 Day change
-2.02%
52 Week Range
71.500
Analysis Updated At
2026/04/24
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Uniqure NV (QURE) is not a strong buy for a beginner, long-term investor at this moment. While there are some positive catalysts, the financial performance and regulatory uncertainties make it prudent to hold off on investment until clearer signals emerge.

Technical Analysis

The technical indicators are neutral. The MACD is positive but contracting, RSI is neutral at 54.598, and moving averages are converging. The stock is trading near its pivot level of 16.575, with resistance at 18.874 and support at 14.275.

Options Data

Bullish
Open Interest Put-Call Ratio
Bearish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
5
Buy
10

Positive Catalysts

  • Analysts like Mizuho, RBC, and Wells Fargo have upgraded the stock recently, citing potential for regulatory approval and commercial uptake.

Neutral/Negative Catalysts

  • The company faces regulatory uncertainty, with a potential Phase 3 trial for AMT-130 that could delay progress by three-plus years. Insider and hedge fund trading trends are neutral, and there is no recent news to drive momentum.

Financial Performance

In Q4 2025, revenue increased by 6.65% YoY to $5.57 million, but net income dropped by -49.38% YoY to -$37.09 million. EPS fell by -60.67% YoY to -0.59. Gross margin improved to 92.19%, up 4.59% YoY, but the overall financials indicate significant losses.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analyst sentiment is mixed. Recent upgrades from Mizuho, RBC, and Wells Fargo highlight potential regulatory improvements and a positive outlook for AMT-130. However, Barclays and Chardan have expressed concerns about regulatory delays and uncertainty, leading to lower price targets.

Wall Street analysts forecast QURE stock price to rise
10 Analyst Rating
Wall Street analysts forecast QURE stock price to rise
8 Buy
2 Hold
0 Sell
Strong Buy
Current: 27.660
sliders
Low
33
Averages
49.88
High
70
Current: 27.660
sliders
Low
33
Averages
49.88
High
70
H.C. Wainwright
Patrick Trucchio
Buy
downgrade
$70 -> $50
AI Analysis
2026-05-06
New
Reason
H.C. Wainwright
Patrick Trucchio
Price Target
$70 -> $50
AI Analysis
2026-05-06
New
downgrade
Buy
Reason
H.C. Wainwright analyst Patrick Trucchio lowered the firm's price target on uniQure to $50 from $70 and keeps a Buy rating on the shares after the company reported Q1 results and provided updates across its gene therapy pipeline. AMT-130 timing risk has increased in the U.S., but the U.K. path "now provides a credible route to first approval" and the firm continues to view AMT-130 as having "the strongest clinical dataset generated" in Huntington's disease, the analyst tells investors.
Stifel
Paul Matteis
Buy
maintain
$14 -> $28
2026-05-05
Reason
Stifel
Paul Matteis
Price Target
$14 -> $28
2026-05-05
maintain
Buy
Reason
Stifel analyst Paul Matteis raised the firm's price target on uniQure to $28 from $14 and keeps a Buy rating on the shares. The firm reiterated its Buy view following the company's Q1 update, where the company remains on track to have a Type B meeting with the FDA in 2Q26. While the firm isn't expecting an imminent FDA 180, what will be interesting here is tot see how uniQure can try to preserve some optionality with the four-year data cut, the analyst tells investors in a research note.
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