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QURE Should I Buy

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Intellectia

Should You Buy Uniqure NV (QURE) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
17.560
1 Day change
-3.83%
52 Week Range
71.500
Analysis Updated At
2026/03/06
Should I buy Analysis is updated weekly. For real time "Should I Buy" analysis, please sign up to get free answers.
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Uniqure NV (QURE) is not a good buy at this time for a beginner investor with a long-term strategy. The stock faces significant regulatory hurdles, negative sentiment from analysts, and weak financial performance. Despite a slight revenue increase, the company's net income and EPS have significantly declined. The technical indicators also suggest bearish momentum. Given the lack of positive catalysts and the uncertain future of its key drug pipeline, holding off on this investment is the prudent choice.

Technical Analysis

The technical indicators for QURE are bearish. The MACD histogram is negative and contracting, RSI is neutral but leaning towards oversold territory, and the moving averages indicate a downward trend (SMA_200 > SMA_20 > SMA_5). The stock is trading near its support level of 10.633, with resistance levels at 17.009 and 23.384.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
8
Buy
3

Positive Catalysts

  • The company's gross margin increased to 92.19%, up 4.59% YoY, which is a positive sign for operational efficiency.

Neutral/Negative Catalysts

  • The FDA's requirement for a new sham surgery-controlled Phase 3 trial for AMT-130 in Huntington's disease is a significant setback. Analysts have downgraded the stock and drastically reduced price targets. Additionally, a class action lawsuit has been filed against the company, further damaging investor sentiment.

Financial Performance

In Q4 2025, revenue increased by 6.65% YoY to $5,568,000. However, net income dropped by 49.38% YoY to -$37,086,000, and EPS fell by 60.67% YoY to -0.59, indicating worsening profitability.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts have overwhelmingly downgraded the stock, with price targets significantly reduced. The consensus is that the regulatory hurdles for AMT-130 will delay approval by several years, diminishing investor confidence in the company's pipeline and future growth prospects.

Wall Street analysts forecast QURE stock price to rise
10 Analyst Rating
Wall Street analysts forecast QURE stock price to rise
8 Buy
2 Hold
0 Sell
Strong Buy
Current: 18.260
sliders
Low
33
Averages
49.88
High
70
Current: 18.260
sliders
Low
33
Averages
49.88
High
70
Mizuho
Neutral -> Outperform
upgrade
$12 -> $35
AI Analysis
2026-03-10
New
Reason
Mizuho
Price Target
$12 -> $35
AI Analysis
2026-03-10
New
upgrade
Neutral -> Outperform
Reason
Mizuho upgraded uniQure to Outperform from Neutral with a price target of $35, up from $12.
Mizuho
Neutral -> Outperform
upgrade
$12 -> $35
2026-03-10
New
Reason
Mizuho
Price Target
$12 -> $35
2026-03-10
New
upgrade
Neutral -> Outperform
Reason
As previously reported, Mizuho upgraded uniQure to Outperform from Neutral with a price target of $35, up from $12, arguing that Friday's "unexpected" announcement that Dr. Vinay Prasad will depart the FDA, just days after a highly public dispute with uniQure, "appears to signal an administration-level desire to restore greater regulatory flexibility in rare disease development." The firm believes this leadership change is "constructive for uniQure," potentially reopening a path to a BLA based on the existing Phase 1/2 data or a Phase 3 trial leveraging natural history controls, the analyst tells investors.
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