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PFE Should I Buy

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Intellectia

Should You Buy Pfizer Inc (PFE) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
27.300
1 Day change
0.52%
52 Week Range
27.940
Analysis Updated At
2026/03/06
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Pfizer Inc (PFE) is not a strong buy at the moment for a beginner investor with a long-term strategy. While the stock offers a high dividend yield and has positive news regarding its obesity drug approval in China, the company's financial performance is weak, and technical indicators suggest a bearish trend. Analyst ratings are mixed, with significant concerns about revenue declines and loss of exclusivity for key drugs. Given the investor's preference for long-term growth, it would be prudent to wait for clearer signs of recovery or stronger growth catalysts before investing.

Technical Analysis

The MACD is negatively expanding (-0.127), indicating bearish momentum. RSI is at 36.789, suggesting the stock is approaching oversold territory but not yet at a buy signal. Moving averages are converging, showing indecision. Key support is at $26.387, with resistance at $27.51. Pre-market price is $26.44, slightly above support, but the overall trend is bearish with a potential for further downside (-1.48% next day, -4% next week, -8.46% next month).

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Open interest and volume ratios suggest a moderately bullish sentiment in the options market, but not strong enough to counteract the bearish technical and fundamental signals.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
0
Buy
9

Positive Catalysts

  • China's approval of Pfizer's obesity drug Ecnoglutide expands its market presence. The company's dividend yield of 6.3% is attractive for income-focused investors. Argus upgraded the stock to Buy with a $35 price target, citing confidence in its GLP-1 and oncology pipelines.

Neutral/Negative Catalysts

  • Weak financial performance in Q4 2025, with revenue down 1.16% YoY, net income down 501.95% YoY, and EPS down 514.29% YoY. Analysts have expressed concerns about revenue cliffs from loss of exclusivity for key drugs, with no near-term catalysts to offset these losses. Technical indicators suggest a bearish trend, and stock trend analysis predicts further downside in the short term.

Financial Performance

In Q4 2025, revenue decreased by 1.16% YoY to $17.56 billion. Net income dropped significantly to -$1.65 billion, a decline of 501.95% YoY. EPS fell to -$0.29, down 514.29% YoY. However, gross margin improved to 64.15%, up 6% YoY, indicating some operational efficiency improvements.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analyst ratings are mixed. Argus recently upgraded the stock to Buy with a $35 price target, citing confidence in its pipeline. However, RBC Capital and Barclays initiated coverage with Underperform and Underweight ratings, respectively, citing revenue cliffs and lack of near-term catalysts. The average price target ranges between $25 and $35, reflecting uncertainty in the stock's near-term performance.

Wall Street analysts forecast PFE stock price to rise
16 Analyst Rating
Wall Street analysts forecast PFE stock price to rise
5 Buy
11 Hold
0 Sell
Moderate Buy
Current: 27.160
sliders
Low
24
Averages
28.56
High
35
Current: 27.160
sliders
Low
24
Averages
28.56
High
35
Argus
Hold
to
Buy
upgrade
$35
AI Analysis
2026-03-02
Reason
Argus
Price Target
$35
AI Analysis
2026-03-02
upgrade
Hold
to
Buy
Reason
Argus upgraded Pfizer to Buy from Hold with a $35 price target. The firm is positive on the company's recent additions to its GLP-1 pipeline along with its "robust" programs in oncology and hematology, saying it has greater confidence in Pfizer's ability to grow the top and bottom lines in post-2028 period, the analyst tells investors in a research note. Beyond 2028, Argus notes Pfizer's accelerated R&D, successful launch of new products and bolt-on business development.
Argus
Hold
to
Buy
upgrade
$35
2026-03-02
Reason
Argus
Price Target
$35
2026-03-02
upgrade
Hold
to
Buy
Reason
Argus upgraded Pfizer to Buy from Hold with a $35 price target.
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