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PCVX Should I Buy

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Intellectia

Should You Buy Vaxcyte Inc (PCVX) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
54.670
1 Day change
-2.27%
52 Week Range
73.760
Analysis Updated At
2026/03/20
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Vaxcyte Inc (PCVX) does not currently present a strong buy opportunity for a beginner investor with a long-term strategy. While the company has promising catalysts like the VAX-31 Phase 3 data and strong analyst support, the technical indicators and financial performance suggest caution. The stock is trading near a key support level, and there are no immediate signals or news to suggest a significant upward movement in the short term.

Technical Analysis

The MACD is below 0 and negatively contracting, indicating bearish momentum. RSI is neutral at 25.473, and moving averages are converging, showing no clear trend. The stock is trading near its S1 support level of 53.96, with resistance at 56.714. Overall, the technical indicators suggest a lack of strong upward momentum.

Options Data

Bearish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

The high Open Interest Put-Call Ratio indicates bearish sentiment, while the low Option Volume Put-Call Ratio suggests limited trading activity on the bearish side.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
6
Buy
5

Positive Catalysts

  • Strong analyst support with multiple Buy ratings and increased price targets, driven by the promising potential of VAX-31 and its Phase 3 data. Analysts view the vaccine as having best-in-class potential for both adults and children.

Neutral/Negative Catalysts

  • No significant news or events in the past week. Financial performance remains weak, with negative net income and EPS despite YoY improvement. Hedge funds and insiders show neutral trading trends, indicating no strong institutional or insider confidence.

Financial Performance

In Q4 2025, the company reported a net income of -$246.5 million, improving 79.83% YoY. EPS increased to -1.81, up 79.21% YoY. However, revenue and gross margin remain at 0, indicating no revenue generation yet.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are bullish overall, with multiple Buy ratings and price targets ranging from $67 to $133. Key catalysts include the upcoming Phase 3 adult data and Phase 2 pediatric readouts for VAX-31. However, one analyst maintains a Neutral rating, citing slower-than-expected competitive developments.

Wall Street analysts forecast PCVX stock price to rise
6 Analyst Rating
Wall Street analysts forecast PCVX stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 54.670
sliders
Low
50
Averages
104.8
High
163
Current: 54.670
sliders
Low
50
Averages
104.8
High
163
TD Cowen
Tara Bancroft
Buy
upgrade
$50 -> $75
AI Analysis
2026-02-25
Reason
TD Cowen
Tara Bancroft
Price Target
$50 -> $75
AI Analysis
2026-02-25
upgrade
Buy
Reason
TD Cowen analyst Tara Bancroft raised the firm's price target on Vaxcyte to $75 from $50 and keeps a Buy rating on the shares. The firm said Vaxcyte enters 2026 with a largely de-risked path for VAX-31, supported by differentiated Phase II data and a comprehensive Phase III OPUS program targeting BLA filing in 2027.
Goldman Sachs
Neutral
maintain
$38 -> $67
2026-02-25
Reason
Goldman Sachs
Price Target
$38 -> $67
2026-02-25
maintain
Neutral
Reason
Goldman Sachs raised the firm's price target on Vaxcyte to $67 from $38 and keeps a Neutral rating on the shares. Since coverage initiation, shares have risen steadily due to clinical progress on VAX-31, a slower-than-expected competitive landscape, and stable policy around the 4-dose infant schedule, contributing to year-to-date outperformance, the analyst tells investors in a research note. Upcoming VAX-31 Phase 3 adult data, Phase 2 pediatric readouts, and competitive developments viewed as key de-risking catalysts, the firm adds.
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