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MNPR Should I Buy

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Intellectia

Should You Buy Monopar Therapeutics Inc (MNPR) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
58.470
1 Day change
0.69%
52 Week Range
105.000
Analysis Updated At
2026/03/06
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Monopar Therapeutics Inc (MNPR) is not a strong buy for a beginner, long-term investor at this time. The lack of significant positive financial performance, absence of recent news catalysts, and neutral trading trends suggest that the stock does not currently present a compelling long-term investment opportunity. The technical indicators and lack of proprietary trading signals further reinforce a hold recommendation.

Technical Analysis

The MACD is positive and expanding, suggesting slight bullish momentum. However, the RSI is neutral at 53.357, and the moving averages indicate a bearish trend (SMA_200 > SMA_20 > SMA_5). The stock is trading near its pivot level of 55, with resistance at 59.733 and support at 51.657. Overall, the technical indicators do not strongly support a buy decision.

Positive Catalysts

  • Morgan Stanley's Overweight rating and $115 price target, citing the potential of ALXN1840 as a differentiated therapy for Wilson's disease, provide a positive long-term outlook.

Neutral/Negative Catalysts

  • No recent news or significant trading trends from hedge funds or insiders. Financial performance remains weak, with no revenue and negative net income. Stock trend analysis indicates a potential short-term decline (-1.97% in the next day, -3.65% in the next week).

Financial Performance

In Q3 2025, the company reported no revenue growth (0% YoY) and a net income of -$3,437,601, which improved by 163.56% YoY but remains negative. EPS improved to -0.48, up 29.73% YoY, but still negative. Gross margin remains at 0%. Overall, the financials do not indicate strong growth or profitability.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Morgan Stanley initiated coverage with an Overweight rating and a $115 price target, citing the potential of ALXN1840 as a differentiated therapy for Wilson's disease. This suggests a positive long-term outlook but does not align with the current weak financials and trading sentiment.

Wall Street analysts forecast MNPR stock price to rise
11 Analyst Rating
Wall Street analysts forecast MNPR stock price to rise
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 58.070
sliders
Low
95
Averages
112.91
High
130
Current: 58.070
sliders
Low
95
Averages
112.91
High
130
Morgan Stanley
Maxwell Skor
Overweight
initiated
$115
AI Analysis
2026-01-09
Reason
Morgan Stanley
Maxwell Skor
Price Target
$115
AI Analysis
2026-01-09
initiated
Overweight
Reason
Morgan Stanley analyst Maxwell Skor initiated coverage of Monopar Therapeutics with an Overweight rating and $115 price target. The firm says ALXN1840 demonstrated "meaningful" copper mobilization and neurological benefit in a Phase 3 study as a "differentiated therapy" for Wilson's disease with a once-daily profile. The analyst sees an "encouraging set-up" for the shares.
Raymond James
Christopher Raymond
Strong Buy -> Outperform
downgrade
$142 -> $123
2025-11-14
Reason
Raymond James
Christopher Raymond
Price Target
$142 -> $123
2025-11-14
downgrade
Strong Buy -> Outperform
Reason
Raymond James analyst Christopher Raymond downgraded Monopar Therapeutics to Outperform from Strong Buy with a price target of $123, down from $142. The firm cites a higher risk profile than anticipated for the downgrade. The firm's key opinion leader feedback indicates a "heavier commercial" lift than first imagined for Monopar in Wilson disease. A " higher risk premium to our estimates is warranted here," the analyst tells investors in a research note.
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