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MNPR Should I Buy

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Intellectia

Should You Buy Monopar Therapeutics Inc (MNPR) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
65.520
1 Day change
3.06%
52 Week Range
105.000
Analysis Updated At
2026/04/24
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Monopar Therapeutics Inc (MNPR) is not a strong buy at this time for a beginner investor with a long-term focus. The technical indicators are bearish, the financial performance is weak, and there are no significant positive trading trends or proprietary trading signals. While the recent clinical trial results are promising, they are not immediate catalysts for price growth, and the company's financial health raises concerns for long-term investment.

Technical Analysis

The technical indicators are bearish. The MACD is negatively expanding (-0.271), the RSI is neutral at 31.919, and the moving averages show a bearish trend (SMA_200 > SMA_20 > SMA_5). The stock is trading near its support level (S1: 52.559), with resistance levels at R1: 58.992 and R2: 60.979.

Positive Catalysts

  • Monopar released positive clinical trial results for ALXN1840, showing significant neurologic improvements in Wilson disease patients. The company plans to submit a New Drug Application to the FDA in mid-2026, indicating potential long-term growth opportunities.

Neutral/Negative Catalysts

  • Additionally, there are no significant insider or hedge fund trading trends, and the stock's technical indicators are bearish.

Financial Performance

In Q4 2025, Monopar reported zero revenue growth (0.00% YoY), a net income drop to -$5,200,795 (-52.40% YoY), and a significant EPS decline to -0.61 (-72.65% YoY). Gross margin remained at 0, showing no improvement.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

No analyst rating or price target changes are available for MNPR at this time.

Wall Street analysts forecast MNPR stock price to rise
11 Analyst Rating
Wall Street analysts forecast MNPR stock price to rise
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 63.575
sliders
Low
95
Averages
112.91
High
130
Current: 63.575
sliders
Low
95
Averages
112.91
High
130
Morgan Stanley
Maxwell Skor
Overweight
initiated
$115
AI Analysis
2026-01-09
Reason
Morgan Stanley
Maxwell Skor
Price Target
$115
AI Analysis
2026-01-09
initiated
Overweight
Reason
Morgan Stanley analyst Maxwell Skor initiated coverage of Monopar Therapeutics with an Overweight rating and $115 price target. The firm says ALXN1840 demonstrated "meaningful" copper mobilization and neurological benefit in a Phase 3 study as a "differentiated therapy" for Wilson's disease with a once-daily profile. The analyst sees an "encouraging set-up" for the shares.
Raymond James
Christopher Raymond
Strong Buy -> Outperform
downgrade
$142 -> $123
2025-11-14
Reason
Raymond James
Christopher Raymond
Price Target
$142 -> $123
2025-11-14
downgrade
Strong Buy -> Outperform
Reason
Raymond James analyst Christopher Raymond downgraded Monopar Therapeutics to Outperform from Strong Buy with a price target of $123, down from $142. The firm cites a higher risk profile than anticipated for the downgrade. The firm's key opinion leader feedback indicates a "heavier commercial" lift than first imagined for Monopar in Wilson disease. A " higher risk premium to our estimates is warranted here," the analyst tells investors in a research note.
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