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MNPR Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
54.970
Open
53.540
VWAP
53.89
Vol
77.93K
Mkt Cap
361.53M
Low
51.760
Amount
4.20M
EV/EBITDA(TTM)
--
Total Shares
6.68M
EV
221.13M
EV/OCF(TTM)
--
P/S(TTM)
--
Monopar Therapeutics Inc. is a clinical-stage biopharmaceutical company. The Company developing treatments for Wilson disease and novel radiopharmaceuticals for oncology. The Company’s product candidates are ALXN1840, MNPR-101, MNPR-101-Zr, MNPR-101-Lu, and MNPR-101-Ac. The Company’s Wilson disease product candidate is ALXN1840, a late-stage, investigational once-daily, oral medicine. Its radiopharmaceutical program consists of MNPR-101, a proprietary humanized monoclonal antibody that is being developed across multiple product candidates conjugated with different radioisotopes, for the treatment of advanced solid tumors. MNPR-101-Zr is the Company’s clinical-stage radiodiagnostic imaging agent comprised of MNPR-101 conjugated to zirconium-89. MNPR-101-Lu is its clinical-stage radiotherapeutic comprised of MNPR-101 conjugated to lutetium-177. MNPR-101-Ac is late-preclinical stage radiotherapeutic comprised of MNPR-101 conjugated to actinium-225.
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Events Timeline

(ET)
2026-03-02
08:10:00
Monopar Therapeutics Appoints Susan Rodriguez as Chief Commercial and Strategy Officer
select
2025-11-13 (ET)
2025-11-13
08:02:27
Monopar Therapeutics Announces Quarterly EPS of 48 Cents, Exceeding Consensus Estimate of 40 Cents
select
2025-11-09 (ET)
2025-11-09
13:31:07
Monopar unveils fresh data and analyses from the Phase 2 ALXN1840-WD-204 study
select

News

seekingalpha
9.5
03-27seekingalpha
Monopar Therapeutics Reports Q4 Earnings Miss
  • Earnings Report Disappointment: Monopar Therapeutics reported a Q4 GAAP EPS of -$0.61, missing expectations by $0.16, indicating challenges in profitability that may affect investor confidence.
  • Cash Position Overview: As of December 31, 2025, the company had $140.4 million in cash, cash equivalents, and short-term investments, which, while providing some liquidity, raises concerns about capital efficiency and future funding needs.
  • Market Reaction Analysis: The earnings miss has led to market concerns regarding Monopar's growth potential, likely putting downward pressure on the stock price and impacting its competitive position in the biopharmaceutical sector.
  • Investor Focus: Analysts' quant ratings on Monopar Therapeutics reflect market scrutiny over its financial health, prompting investors to closely monitor future financial performance and strategic adjustments.
Newsfilter
9.5
03-27Newsfilter
Monopar Reports 2025 Financial Results and Drug Development Updates
  • Financial Performance Boost: Monopar completed an underwritten public offering generating approximately $91.9 million in 2025, significantly strengthening its balance sheet, with current funds expected to support operations through December 31, 2027, ensuring smooth regulatory and commercial activities for ALXN1840.
  • Significant R&D Progress: The NDA for ALXN1840 targeting Wilson disease is planned for submission in mid-2026, with recent presentations at EASL and ANA showcasing long-term efficacy and safety data from 255 patients, indicating statistically significant improvements in copper balance.
  • Leadership Team Strengthening: Monopar appointed Susan Rodriguez as Chief Commercial and Strategy Officer to prepare for the potential launch of ALXN1840, further enhancing the company's competitive position in the Wilson disease treatment market.
  • R&D Expense Control: R&D expenses for Q4 2025 were $3.9 million, significantly down from $9.9 million in Q4 2024, primarily due to the absence of one-time costs, while reflecting increased investments in personnel and clinical materials.
moomoo
9.5
03-27moomoo
MONOPAR RELEASES FINANCIAL RESULTS FOR FOURTH QUARTER AND FULL YEAR 2025 ALONG WITH BUSINESS UPDATE
  • Financial Results Overview: The report presents the financial results for the fourth quarter and the full year of 2025, highlighting key performance metrics and overall financial health.

  • Business Update: The document provides a comprehensive business update, detailing operational developments and strategic initiatives undertaken during the reporting period.

CNBC
6.0
01-09CNBC
Goldman Sachs Cuts Netflix Price Target to $112 Ahead of Earnings
  • Price Target Adjustment: Goldman Sachs has cut its price target for Netflix from $130 to $112, reflecting a cautious outlook ahead of the upcoming earnings report, which is expected to show solid performance by the end of 2025 as management executes its core strategic focus.
  • Content Strategy: Goldman emphasizes that Netflix will continue to rely on original and returning original content to drive user engagement and growth, a strategy that may impact user retention and market share in the competitive streaming landscape.
  • Market Expectations: While Goldman maintains a neutral rating on Netflix, the market's reaction to the forthcoming earnings report could lead to stock price volatility, particularly given the uncertainties in the macroeconomic environment.
  • Competitive Pressure: Netflix faces competitive pressures from other streaming platforms, especially regarding content richness and user experience, which could affect its growth potential moving forward.
Benzinga
7.5
2025-12-31Benzinga
Biotech Stocks Surge at Year-End 2025, ETFs Gain 35.84%
  • Sector Recovery: The iShares Biotechnology ETF surged 29.51% year-to-date by December 2025, while the State Street SPDR S&P Biotech ETF achieved an even higher gain of 35.84%, indicating a significant recovery in investor confidence in the biotech sector.
  • Surge in M&A Activity: Six of the year's ten largest biopharma deals occurred in Q4, with Johnson & Johnson spending $14.6 billion on Intra Cellular Therapies, signaling a strong commitment from big pharma to expand their pipelines through acquisitions.
  • FDA Approvals Boost Innovation: The FDA approved 44 new therapies in 2025, with 26 approvals in the second half, including Cytokinetics' Myqorzo after 27 years, highlighting a supportive regulatory environment for innovation.
  • Clinical Trial Successes: Structure Therapeutics saw its stock more than double after its obesity drug trials showed over 15% weight loss in patients, demonstrating the direct impact of clinical success on company valuations.
NASDAQ.COM
5.0
2025-12-29NASDAQ.COM
Monopar CFO Vu Acquires 1,500 Shares of MNPR for $104,925
  • Insider Purchase: Monopar Therapeutics CFO Quan Anh Vu purchased 1,500 shares of MNPR at $69.95 each on Friday, totaling an investment of $104,925, indicating confidence in the company's future prospects.
  • Market Reaction: Despite Vu's purchase signaling optimism about the company's outlook, MNPR's stock fell approximately 1.1% on Monday, reflecting market caution regarding the company's current situation.
  • Purchase Frequency: This marks Vu's first stock purchase in the past 12 months, potentially indicating a reassessment of the company's value or expectations for future performance.
  • Investor Confidence: Insider buying is generally viewed as a positive signal for the company's future, which may bolster confidence among other investors, even though the stock's short-term performance remains weak.
Wall Street analysts forecast MNPR stock price to rise
11 Analyst Rating
Wall Street analysts forecast MNPR stock price to rise
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
95.00
Averages
112.91
High
130.00
Current: 0.000
sliders
Low
95.00
Averages
112.91
High
130.00
Morgan Stanley
Maxwell Skor
Overweight
initiated
$115
AI Analysis
2026-01-09
Reason
Morgan Stanley
Maxwell Skor
Price Target
$115
AI Analysis
2026-01-09
initiated
Overweight
Reason
Morgan Stanley analyst Maxwell Skor initiated coverage of Monopar Therapeutics with an Overweight rating and $115 price target. The firm says ALXN1840 demonstrated "meaningful" copper mobilization and neurological benefit in a Phase 3 study as a "differentiated therapy" for Wilson's disease with a once-daily profile. The analyst sees an "encouraging set-up" for the shares.
Raymond James
Christopher Raymond
Strong Buy -> Outperform
downgrade
$142 -> $123
2025-11-14
Reason
Raymond James
Christopher Raymond
Price Target
$142 -> $123
2025-11-14
downgrade
Strong Buy -> Outperform
Reason
Raymond James analyst Christopher Raymond downgraded Monopar Therapeutics to Outperform from Strong Buy with a price target of $123, down from $142. The firm cites a higher risk profile than anticipated for the downgrade. The firm's key opinion leader feedback indicates a "heavier commercial" lift than first imagined for Monopar in Wilson disease. A " higher risk premium to our estimates is warranted here," the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for MNPR
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Valuation Metrics

The current forward P/E ratio for Monopar Therapeutics Inc (MNPR.O) is -22.16, compared to its 5-year average forward P/E of -6.28. For a more detailed relative valuation and DCF analysis to assess Monopar Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-6.28
Current PE
-22.16
Overvalued PE
1.13
Undervalued PE
-13.69

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
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Quarterly

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Whales Holding MNPR

V
Vivo Capital, LLC
Holding
MNPR
+7.46%
3M Return
A
Artal Group S.A.
Holding
MNPR
+0.12%
3M Return
T
TCG Crossover Management, LLC
Holding
MNPR
-4.78%
3M Return
R
RA Capital Management, L.P.
Holding
MNPR
-7.24%
3M Return
D
Deep Track Capital, LP
Holding
MNPR
-15.40%
3M Return

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Frequently Asked Questions

What is Monopar Therapeutics Inc (MNPR) stock price today?

The current price of MNPR is 54.93 USD — it has increased 1.53

What is Monopar Therapeutics Inc (MNPR)'s business?

Monopar Therapeutics Inc. is a clinical-stage biopharmaceutical company. The Company developing treatments for Wilson disease and novel radiopharmaceuticals for oncology. The Company’s product candidates are ALXN1840, MNPR-101, MNPR-101-Zr, MNPR-101-Lu, and MNPR-101-Ac. The Company’s Wilson disease product candidate is ALXN1840, a late-stage, investigational once-daily, oral medicine. Its radiopharmaceutical program consists of MNPR-101, a proprietary humanized monoclonal antibody that is being developed across multiple product candidates conjugated with different radioisotopes, for the treatment of advanced solid tumors. MNPR-101-Zr is the Company’s clinical-stage radiodiagnostic imaging agent comprised of MNPR-101 conjugated to zirconium-89. MNPR-101-Lu is its clinical-stage radiotherapeutic comprised of MNPR-101 conjugated to lutetium-177. MNPR-101-Ac is late-preclinical stage radiotherapeutic comprised of MNPR-101 conjugated to actinium-225.

What is the price predicton of MNPR Stock?

Wall Street analysts forecast MNPR stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MNPR is112.91 USD with a low forecast of 95.00 USD and a high forecast of 130.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Monopar Therapeutics Inc (MNPR)'s revenue for the last quarter?

Monopar Therapeutics Inc revenue for the last quarter amounts to -6.16M USD, decreased -44.42

What is Monopar Therapeutics Inc (MNPR)'s earnings per share (EPS) for the last quarter?

Monopar Therapeutics Inc. EPS for the last quarter amounts to -3370070.00 USD, increased 68.64

How many employees does Monopar Therapeutics Inc (MNPR). have?

Monopar Therapeutics Inc (MNPR) has 22 emplpoyees as of March 31 2026.

What is Monopar Therapeutics Inc (MNPR) market cap?

Today MNPR has the market capitalization of 361.53M USD.