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MLYS Should I Buy

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Intellectia

Should You Buy Mineralys Therapeutics Inc (MLYS) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Buy
Latest Price
28.530
1 Day change
5.32%
52 Week Range
47.650
Analysis Updated At
2026/03/27
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Mineralys Therapeutics Inc (MLYS) presents a strong long-term investment opportunity for a beginner investor with $50,000-$100,000 available for investment. Despite short-term technical weakness, the significant upside potential of 114.78% based on analyst targets, hedge fund buying activity, and promising clinical developments for its lead drug lorundrostat make this a compelling buy.

Technical Analysis

The technical indicators suggest a bearish short-term trend. The MACD is below zero and negatively contracting, RSI is neutral at 38.702, and moving averages show a bearish alignment (SMA_200 > SMA_20 > SMA_5). The stock is currently trading near its support level (S1: 22.742).

Options Data

Bearish
Open Interest Put-Call Ratio
Bearish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
5
Buy
5

Positive Catalysts

  • Analysts have raised the price target to $51, citing underappreciated peak sales potential for lorundrostat.

  • Hedge funds are significantly increasing their positions, with a 516.79% increase in buying over the last quarter.

  • The stock has a potential upside of 114.78% based on current price and analyst target.

Neutral/Negative Catalysts

  • Weak financial performance in Q4 2025, with net income dropping by 34.14% YoY and EPS declining by 59.18%.

  • Short-term technical indicators are bearish, suggesting potential near-term price weakness.

Financial Performance

In Q4 2025, the company reported no revenue growth (0% YoY), a net income loss of -$32.23M (down 34.14% YoY), and a significant EPS decline of 59.18%. Gross margin remained at 0%.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are bullish, with BofA raising the price target to $51 from $46 and maintaining a Buy rating. They believe the peak sales opportunity for lorundrostat is underappreciated, signaling confidence in the company's future growth.

Wall Street analysts forecast MLYS stock price to rise
6 Analyst Rating
Wall Street analysts forecast MLYS stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 27.090
sliders
Low
46
Averages
52.6
High
56
Current: 27.090
sliders
Low
46
Averages
52.6
High
56
BofA
Buy
maintain
$46 -> $51
AI Analysis
2026-03-13
Reason
BofA
Price Target
$46 -> $51
AI Analysis
2026-03-13
maintain
Buy
Reason
BofA raised the firm's price target on Mineralys Therapeutics to $51 from $46 and keeps a Buy rating on the shares following some corporate updates on the clinical development progress of lead drug lorundrostat for the treatment of uncontrolled hypertension that came with Q4 earnings. The firm's view is that lorundrostat's peak sales opportunity remains "underappreciated," the analyst tells investors.
Stifel
Buy
maintain
$45 -> $52
2025-12-19
Reason
Stifel
Price Target
$45 -> $52
2025-12-19
maintain
Buy
Reason
Stifel raised the firm's price target on Mineralys Therapeutics to $52 from $45 and keeps a Buy rating on the shares as part of a 2026 outlook note for the analyst's Biopharma coverage.
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