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MIST Should I Buy

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Intellectia

Should You Buy Milestone Pharmaceuticals Inc (MIST) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
1.160
1 Day change
14.36%
52 Week Range
3.060
Analysis Updated At
2026/03/27
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Milestone Pharmaceuticals Inc (MIST) is not a good buy for a beginner investor with a long-term strategy at this time. The technical indicators are bearish, the options data shows weak sentiment, and the company's financial performance is poor with consistent losses. Additionally, analysts have downgraded the stock to a 'Sell' rating, and there are no strong positive catalysts to justify an investment.

Technical Analysis

The technical indicators for MIST are bearish. The MACD histogram is negative and expanding downward, the RSI is neutral but low at 22.38, and the moving averages indicate a bearish trend (SMA_200 > SMA_20 > SMA_5). The stock is trading below key support levels, with the next support at 1.199 and resistance at 1.458.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

The low put-call ratios indicate weak bearish sentiment, but the overall low trading activity and high implied volatility (193.48) suggest significant uncertainty and risk.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
9
Buy
6

Positive Catalysts

  • The company has announced plans for a Phase 3 program for Etripamil, which could be a long-term growth driver if successful.

Neutral/Negative Catalysts

  • The company reported a net loss of $17.4 million in Q4 2025 and a full-year loss of $63.1 million. Analysts have downgraded the stock to a 'Sell' rating following poor financial performance. Additionally, the stock's technical indicators and options data do not support a bullish outlook.

Financial Performance

In Q4 2025, the company reported $1.55 million in revenue, which remained flat YoY. Net income improved to -$17.4 million, up 40.82% YoY, but EPS dropped to -$0.16, down 15.79% YoY. The company continues to operate at a loss, and its financials do not indicate strong growth potential.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts have downgraded the stock to a 'Sell' rating following the company's poor financial performance and limited revenue growth.

Wall Street analysts forecast MIST stock price to rise
3 Analyst Rating
Wall Street analysts forecast MIST stock price to rise
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 1.010
sliders
Low
8
Averages
8
High
8
Current: 1.010
sliders
Low
8
Averages
8
High
8
Wells Fargo
Mohit Bansal
upgrade
$4 -> $8
AI Analysis
2025-12-16
Reason
Wells Fargo
Mohit Bansal
Price Target
$4 -> $8
AI Analysis
2025-12-16
upgrade
Reason
Wells Fargo analyst Mohit Bansal raised the firm's price target on Milestone Pharmaceuticals to $8 from $4 and keeps an Overweight rating on the shares. The firm says Cardamyst's robust label, its reasonable pricing and management's launch strategy bode well for a strong launch. Wells continues to see upside potential to stock despite recent strong performance.
H.C. Wainwright
Brandon Folkes
Buy
upgrade
$5 -> $8
2025-12-15
Reason
H.C. Wainwright
Brandon Folkes
Price Target
$5 -> $8
2025-12-15
upgrade
Buy
Reason
H.C. Wainwright analyst Brandon Folkes raised the firm's price target on Milestone Pharmaceuticals to $8 from $5 and keeps a Buy rating on the shares following the approval of Cardamyst for the treatment of paroxysmal supraventricular tachycardia. The shares at curet levels underappreciate the commercial opportunity of Cardamyst in PSVT, the analyst tells investors in a research note. H.C. Wainwright expects commercial outperformance and the re-initiation of the AFib-RVR trial to drive share momentum over the next 12 to 18 months.
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