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CRSP Should I Buy

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Intellectia

Should You Buy CRISPR Therapeutics AG (CRSP) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
44.340
1 Day change
-3.08%
52 Week Range
78.480
Analysis Updated At
2026/03/27
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CRISPR Therapeutics AG (CRSP) is not a strong buy for a beginner, long-term investor at the moment. While the company has potential due to its innovative pipeline and clinical updates, the technical indicators, insider selling, and recent financial performance suggest caution. The stock may be worth monitoring for future entry points, but it is not an ideal buy right now.

Technical Analysis

The technical indicators suggest a bearish trend. The MACD is below zero and negatively contracting, RSI is neutral at 40.968, and moving averages are bearish (SMA_200 > SMA_20 > SMA_5). The current price of $47.72 is near the pivot level of $47.64, with resistance at $49.576 and support at $45.703.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

The low put-call ratios indicate bullish sentiment in the options market, but the overall volume is relatively low, suggesting limited trading activity.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
10
Buy
3

Positive Catalysts

  • Analysts have raised price targets recently, with Piper Sandler setting a target of $110 and Citi at $80, reflecting optimism about the company's pipeline and clinical updates.

  • The company raised $585.2 million through a convertible note offering, strengthening its cash position to $2.56 billion.

Neutral/Negative Catalysts

  • Insiders are selling heavily, with a 476.16% increase in selling activity over the last month.

  • The company's Q4 financials showed a significant revenue drop of -97.58% YoY, and net income remains negative at -$130.6 million.

  • Technical indicators are bearish, and the stock is trading below key moving averages.

Financial Performance

In Q4 2025, revenue dropped significantly by -97.58% YoY to $864,000. Net income improved but remains negative at -$130.6 million, up 250.07% YoY. EPS also improved to -1.37, up 211.36% YoY. While gross margin is at 100%, the revenue decline and ongoing losses are concerning.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are mixed but slightly optimistic. Piper Sandler raised the price target to $110 with an Overweight rating, while Citi and Chardan also raised targets to $80 and $76, respectively, with Buy ratings. However, Morgan Stanley maintains an Underweight rating with a target of $33, and JPMorgan lowered its target to $67 while keeping an Overweight rating.

Wall Street analysts forecast CRSP stock price to rise
10 Analyst Rating
Wall Street analysts forecast CRSP stock price to rise
8 Buy
2 Hold
0 Sell
Strong Buy
Current: 45.750
sliders
Low
50
Averages
78.89
High
105
Current: 45.750
sliders
Low
50
Averages
78.89
High
105
Piper Sandler
Overweight
maintain
$105 -> $110
AI Analysis
2026-03-17
Reason
Piper Sandler
Price Target
$105 -> $110
AI Analysis
2026-03-17
maintain
Overweight
Reason
Piper Sandler raised the firm's price target on Crispr Therapeutics to $110 from $105 and keeps an Overweight rating on the shares. The firm notes the company issued $600M note due in March 2031 convertible at $76.56 per share with an effective coupon of 1.73%. Piper estimates Crispr now holds pro forma cash of $2.56B.
Morgan Stanley
Morgan Stanley
Underweight
maintain
$32 -> $33
2026-02-17
Reason
Morgan Stanley
Morgan Stanley
Price Target
$32 -> $33
2026-02-17
maintain
Underweight
Reason
Morgan Stanley raised the firm's price target on Crispr Therapeutics (CRSP) to $33 from $32 and keeps an Underweight rating on the shares. The firm refreshed its Crispr estimates and reviewed incremental pipeline progress after partner Vertex Pharmaceuticals (VRTX) recently reported Q4 Casgevy sales.
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