CRBU News & Events

Caribou announced that the FDA has granted Regenerative Medicine Advanced Therapy designation to CB-011 for relapsed or refractory multiple myeloma. CB-011, an allogeneic anti-BCMA CAR-T cell therapy, is being evaluated in the company's ongoing open-label, multicenter CaMMouflage phase 1 clinical trial evaluating patients with r/r MM.

Reports Q4 revenue $3.94M vs. $2.08M last year. "2025 was a year of strong execution for Caribou as we advance two potentially best-in-class allogeneic CAR-T cell therapy programs," said Rachel Haurwitz, Caribou's president and CEO. "The vispa-cel ANTLER phase 1 data in second-line LBCL patients demonstrated efficacy and durability on par with autologous CAR-T therapy and solidified our confidence that this program is delivering on the promise of an off-the-shelf CAR-T cell therapy with speed, scalability, and access. We continue to engage with the FDA on the pivotal trial design and look forward to reporting longer follow up on the phase 1 data later this year. In addition, we initiated dose expansion of the CB-011 CaMMouflage phase 1 clinical trial for patients with multiple myeloma and look forward to sharing initial dose expansion data and longer follow-up on dose escalation data later this year."