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AQST Should I Buy

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Intellectia

Should You Buy Aquestive Therapeutics Inc (AQST) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
4.200
1 Day change
2.44%
52 Week Range
7.550
Analysis Updated At
2026/05/01
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AQST is not a good buy right now for a beginner long-term investor with $50,000-$100,000 available. The stock has some upside potential if Anaphylm gets back on track, but the current setup is dominated by legal overhang, weak technicals, and no confirmed trading signal. For an impatient buyer, this is not a clean entry.

Technical Analysis

AQST is in a weak near-term trend. MACD histogram is negative, RSI at 45.15 is neutral, and the moving averages are bearish with SMA_200 > SMA_20 > SMA_5, which signals downward pressure. Price at 4.09 is below the pivot 4.196 and only slightly above support at 4.042, so the stock is sitting near support but has not confirmed a reversal. The short-term pattern data suggests only modest upside probability over the next week and month.

Options Data

Bullish
Open Interest Put-Call Ratio
Bearish
Option Volume Put-Call Ratio

Options sentiment is mixed-to-bearish in the near term. Open interest put-call ratio of 0.4 suggests more calls than puts outstanding, but the option volume put-call ratio of 8.91 shows much heavier put activity today, which points to defensive or bearish positioning. Total option volume is elevated versus the 30-day average, implying active speculation. Implied volatility is high at 78.68, so the market is pricing in a large move.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
4
Buy
7

Positive Catalysts

  • ["Oppenheimer initiated coverage with an Outperform rating and $8 target, citing Anaphylm regulatory execution as the key catalyst.", "Alliance Global kept a Buy rating and $9 target, viewing the resubmission path as manageable.", "The March 2026 Type A meeting reportedly gave constructive FDA feedback on PK and human factors study design.", "Revenue in Q4 2025 grew 9.67% year over year."]

Neutral/Negative Catalysts

  • ["Multiple class action lawsuits and securities fraud investigations were filed in late April and May 2026.", "The FDA issued a Complete Response Letter for Anaphylm, delaying the main catalyst.", "Insiders are selling, and selling increased 140.84% over the last month.", "Hedge funds are neutral with no strong accumulation trend.", "Gross margin declined 10.90% year over year in the latest quarter.", "Analyst price targets were cut previously after the CRL, showing reduced confidence in timing."]

Financial Performance

In Q4 2025, revenue rose to $13.02 million, up 9.67% year over year, which is a positive growth sign. However, profitability remains weak: net income was -$31.86 million and EPS was -$0.26, even though both losses improved versus last year. Gross margin fell to 55.16%, down 10.90% year over year, so operational quality is still under pressure.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Recent analyst sentiment is still mostly constructive but cautious. Oppenheimer began coverage with Outperform and an $8 target, while Alliance Global, Leerink, and Lake Street all maintained Buy/Outperform views despite cutting targets after the CRL. The bullish case is that Wall Street sees Anaphylm as a viable approval story with a defined remediation path. The bearish case is that approval timing is delayed, execution risk remains, and the legal/news overhang is now significant.

Wall Street analysts forecast AQST stock price to rise
7 Analyst Rating
Wall Street analysts forecast AQST stock price to rise
7 Buy
0 Hold
0 Sell
Strong Buy
Current: 4.100
sliders
Low
6
Averages
9
High
12
Current: 4.100
sliders
Low
6
Averages
9
High
12
Oppenheimer
Mazahir Alimohamed
Outperform
initiated
$8
AI Analysis
2026-04-24
Reason
Oppenheimer
Mazahir Alimohamed
Price Target
$8
AI Analysis
2026-04-24
initiated
Outperform
Reason
Oppenheimer analyst Mazahir Alimohamed assumed coverage of Aquestive Therapeutics with an Outperform rating and $8 price target. The firm views Aquestive as a regulatory execution story for Anaphylm, with NDA resubmission in Q3 2026 and approval as the primary catalysts. Following the January 2026 CRL, the debate has shifted from differentiation to execution against a defined remediation path centered on packaging, administration, human factors, and a supportive PK study. Importantly, the March 2026 Type A meeting provided clarifying FDA feedback on PK and HF study designs, which Oppenheimer views as constructive, though the path remains not fully de-risked.
Alliance Global
Buy
downgrade
$12 -> $9
2026-03-05
Reason
Alliance Global
Price Target
$12 -> $9
2026-03-05
downgrade
Buy
Reason
Alliance Global lowered the firm's price target on Aquestive Therapeutics to $9 from $12 and keeps a Buy rating on the shares after the company held its Q4 earnings call, highlighting its New Drug Application resubmission scheduled for Q3 2026 for Anaphylm. This comes following the Complete Response Letter issued by the FDA after June 2025 NDA acceptance. Alliance Global values Anaphylm for anaphylaxis at $7.50/share, Libervant for pediatric epilepsy at 25c/share, the base manufacturing revenues, license/royalties, fees, and other tech at $1/share, and net cash less debt at 25c/share for its $9/share value.
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