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ANNX Should I Buy

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Intellectia

Should You Buy Annexon Inc (ANNX) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
6.080
1 Day change
8.77%
52 Week Range
7.180
Analysis Updated At
2026/03/05
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Annexon Inc (ANNX) is not a strong buy at the moment for a beginner investor with a long-term strategy. While the technical indicators show some bullish signs, the lack of significant positive catalysts, weak financial performance, and absence of strong trading signals suggest that it is better to hold off on investing in this stock right now.

Technical Analysis

The MACD is positive and contracting, indicating mild bullish momentum. The RSI is neutral at 53.192, showing no clear overbought or oversold conditions. Moving averages are bullish (SMA_5 > SMA_20 > SMA_200), and the stock is trading near its pivot level of 5.263. However, the price has declined by 2.86% in the regular market and 0.55% in post-market trading, suggesting short-term weakness.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
4
Buy
10

Positive Catalysts

  • Analyst Daniil Gataulin from Chardan has initiated a Buy rating with a $16 price target, citing the commercial potential of the company's complement C1q inhibitors in multiple indications. This could indicate long-term growth potential.

Neutral/Negative Catalysts

  • No significant news or recent trading trends from hedge funds or insiders. The financial performance remains weak with no revenue, significant net losses, and negative EPS despite YoY improvements. The stock has a low chance of significant short-term gains based on historical patterns.

Financial Performance

In Q3 2025, the company reported no revenue growth (0% YoY), a net loss of $54.92M (improved by 57.71% YoY), and an EPS of -0.37 (up 48% YoY). While losses are narrowing, the financials remain weak overall.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Chardan analyst initiated a Buy rating with a $16 price target, citing the potential of the company's pipeline in Guillain-Barre syndrome, geographic atrophy, and Huntington's disease. This indicates optimism for long-term growth but lacks immediate impact.

Wall Street analysts forecast ANNX stock price to rise
6 Analyst Rating
Wall Street analysts forecast ANNX stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 5.590
sliders
Low
8
Averages
16.4
High
27
Current: 5.590
sliders
Low
8
Averages
16.4
High
27
Chardan
Daniil Gataulin
Buy
initiated
$16
AI Analysis
2025-12-23
Reason
Chardan
Daniil Gataulin
Price Target
$16
AI Analysis
2025-12-23
initiated
Buy
Reason
Chardan analyst Daniil Gataulin initiated coverage of Annexon with a Buy rating and $16 price target. The firm cites the commercial potential of the company's complement C1q inhibitors tanruprubart in Guillain-Barre syndrome and vonaprument in geographic atrophy for the Buy rating. It sees additional upside potential from tanruprubart in Huntington's disease.
Wells Fargo
NULL
to
Overweight
upgrade
$14 -> $27
2025-11-19
Reason
Wells Fargo
Price Target
$14 -> $27
2025-11-19
upgrade
NULL
to
Overweight
Reason
Wells Fargo raised the firm's price target on Annexon to $27 from $14 and keeps an Overweight rating on the shares. The firm is raising its probability of success to 55% from 10% that vonaprument's Phase 3 trial in GA will be positive in the second half of 2026. Wells believes the setup offers a significant, asymmetric risk/reward skew with the potential for VC-like upside in the next 12 months.
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