Krystal Biotech Inc Earnings
Krystal Biotech Inc., a commercial-stage biotechnology company, has reported significant earnings growth driven by their innovation in genetic medicines for rare diseases. The company’s 2024 financial performance reflects their strategic advancements in both product commercialization and clinical development. Krystal Biotech has demonstrated a remarkable increase in revenues and net income, underscoring the strength of their business model and the growing demand for their flagship product, VYJUVEK.
Krystal Biotech Inc Results
Below is a table summarizing Krystal Biotech’s key financial metrics for the fourth quarter and full year ended December 31, 2024, compared to the previous year’s performance:
| Metric | Q4 2024 | Q4 2023 | % Change Year-over-Year | Full Year 2024 | Full Year 2023 | % Change Year-over-Year |
|---|---|---|---|---|---|---|
| Total Revenue ($ Million) | 91.1 | 42.1 | 116% | 290.5 | 50.7 | 473% |
| Net Income ($ Million) | 45.5 | 8.7 | 423% | 89.2 | 10.9 | 718% |
| Earnings per Share (Basic) | 1.58 | 0.31 | 410% | 3.12 | 0.40 | 680% |
| Earnings per Share (Diluted) | 1.52 | 0.30 | 407% | 3.00 | 0.39 | 669% |
Krystal Biotech’s earnings reveal robust growth, marked by a substantial increase in net income and earnings per share due to heightened revenue streams primarily from VYJUVEK.
Revenue Breakdown
The company’s revenue predominantly stems from their pioneering gene therapy product, VYJUVEK. For a deeper understanding, here is a breakdown of the revenue performance:
| Segment | Q4 2024 Revenue ($ Million) | Q4 2023 Revenue ($ Million) | % Change Year-over-Year |
|---|---|---|---|
| VYJUVEK Net Product Revenue | 91.1 | – | – |
This extraordinary growth is attributed to VYJUVEK’s high demand and successful market penetration. The company’s focus on securing reimbursement approvals has significantly enhanced accessibility, with over 510 approvals achieved in the U.S. by the start of 2025.
Key Developments
During this quarter, Krystal Biotech achieved several operational milestones:
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VYJUVEK Launch Success : The company's premier gene therapy, VYJUVEK, for treating Dystrophic Epidermolysis Bullosa, recorded net product revenue of $91.1 million during the fourth quarter alone, supported by a gross margin of 95%.
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Advancements in Clinical Trials : - Cystic Fibrosis: The CFF's Therapeutic Development Network sanctioned the KB407 Phase 1 protocol, emphasizing promising advances for cystic fibrosis treatment. - Oncology: Initial clinical data for KB707 in lung cancer therapy showed encouraging results with a notable objective response rate and disease control rate in heavily pre-treated patients, suggesting potential for further development.
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Strong Financial Position : The company maintained a solid balance sheet with $749.6 million in cash and investments at year-end.
Comments from Company Officers
Krish S. Krishnan, Chairman and CEO, commented: “Our commercial and financial strength this past year has been transformative. Building on this foundation, our focus in 2025 will be on maximizing the potential of VYJUVEK globally and advancing our clinical programs.”
Dividends and Share Repurchases
Krystal Biotech’s report does not specify any dividend payouts or share repurchase plans. The focus remains on reinvesting earnings into clinical advancements and supporting infrastructure to sustain growth and development.
Krystal Biotech Inc Stock Forecast
Considering Krystal Biotech's substantial earnings growth and innovative pipeline, the company's stock holds promising potential. Based on current financial performance, ongoing clinical trials, and strategic market expansion, analysts might project a stock price range between a high of $120 to a low of $80 within the next year. These estimates factor in the current market capitalization at over $5.2 billion and the significant post-event price increase of 2.25%.
In summary, Krystal Biotech Inc.’s latest financial results highlight a pivotal year of growth, driven largely by the success of VYJUVEK. The company remains well-positioned to sustain this trajectory as it continues its strategic advancements in genetic medicine, reaffirming its leadership in the biotechnology sector.




