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JAGX Overview

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Intellectia

Loading chart...

High
7.997
Open
7.260
VWAP
7.30
Vol
49.29K
Mkt Cap
2.93M
Low
6.950
Amount
359.94K
EV/EBITDA(TTM)
--
Total Shares
13.02M
EV
45.43M
EV/OCF(TTM)
--
P/S(TTM)
1.28
Jaguar Health, Inc. is a commercial stage pharmaceuticals company. The Company is developing prescription medicines sustainably derived from plants from rainforest areas for people and animals with gastrointestinal distress, specifically associated with overactive bowel, which includes symptoms such as chronic debilitating diarrhea, urgency, bowel incontinence, and cramping pain. Its marketed drug Mytesi, (crofelemer 125 mg delayed-release tablets), is a first-in-class oral botanical drug product approved by the FDA for the symptomatic relief of noninfectious diarrhea in adults with HIV/AIDS on antiretroviral therapy. Its Canalevia-CA1, crofelemer delayed-release tablets drug, is an oral plant-based prescription product that is FDA conditionally approved to treat chemotherapy-induced diarrhea in dogs. It has an exclusive distribution agreement for the sale of Gelclair. It is developing a pipeline of prescription drug product candidates to address unmet needs in gastrointestinal health.
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Events Timeline

(ET)
2026-04-29
20:00:00
Jaguar Animal Health Trading Halted, News Pending
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2026-04-29
08:40:00
Jaguar Health Announces Effectiveness Trial Results for Canalevia-CA1 in Dogs
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2026-04-24 (ET)
2026-04-24
08:40:00
Napo Pharmaceuticals Presents Pediatric IF Study at ESPGHAN Meeting
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2026-04-13 (ET)
2026-04-13
08:40:00
Jaguar Health Leverages AI to Enhance Crofelemer Programs
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2026-04-08 (ET)
2026-04-08
08:40:00
Jaguar Health Completes Effectiveness Study for Canalevia-CA1 in Dogs
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2026-04-07 (ET)
2026-04-07
08:40:00
Mytesi Reports Net Product Revenue of $11.5M in 2025
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2026-03-18 (ET)
2026-03-18
09:10:00
Napo Pharmaceuticals Initiates Single-Blind Extension Phase for MVID Clinical Trial
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News

Newsfilter
9.0
04-29Newsfilter
Jaguar Health Advances Towards Full FDA Approval of Crofelemer
  • Clinical Trial Results: Jaguar Health announced the completion of its effectiveness trial for Crofelemer (Canalevia-CA1) in treating chemotherapy-induced diarrhea, revealing that dogs treated with Canalevia-CA1 achieved normal average daily stool after three days, indicating the drug's potential in canine diarrhea treatment.
  • Positive Owner Feedback: At the study's conclusion, 83% of dog owners reported that Canalevia-CA1 was effective for their dog's diarrhea, with around 40% stating that their dog's diarrhea was completely resolved, showcasing significant efficacy and market demand for the drug.
  • Comparative Analysis: In contrast, only 12.5% of owners whose dogs did not receive any treatment reported improvements, highlighting Canalevia-CA1's unique advantages in treating chemotherapy-induced diarrhea, which could lead to increased market share for the company.
  • Future Plans: Jaguar intends to submit the complete trial data to support full regulatory approval for Crofelemer and seek scientific publication, demonstrating the company's strategic vision to expand treatment options for canine diarrhea, potentially driving future business growth.
NASDAQ.COM
8.5
04-14NASDAQ.COM
Jaguar Health Leverages AI for Crofelemer Treatment Advancement
  • AI Technology Application: Jaguar Health plans to utilize artificial intelligence platforms to advance Crofelemer's application in treating intestinal failure (IF) in both adults and children, mining large datasets to identify links between genetics, histopathology, and clinical manifestations, thereby accelerating the development and FDA approval of new therapies.
  • Orphan Disease Treatment: Crofelemer is used to relieve diarrhea symptoms in HIV/AIDS patients undergoing antiretroviral therapy, and currently, there are no alternative treatments for pediatric microvillus inclusion disease (MVID), highlighting the drug's significance for specific patient populations.
  • Market Performance Recovery: Jaguar Health's stock price rose 5.69% to $0.39 at Monday's close, with premarket trading further increasing by 6.10% to $0.41, reflecting positive market expectations regarding its AI strategy and the potential of Crofelemer.
  • Strategic Implications: By integrating AI technology with the development of Crofelemer, Jaguar Health not only enhances treatment efficacy but also potentially opens new market opportunities in the orphan disease sector, strengthening the company's competitive position in the biopharmaceutical industry.
Yahoo Finance
9.5
04-11Yahoo Finance
Jaguar Health Reports Q4 2025 Earnings Highlights
  • Revenue Growth: Jaguar Health reported a net revenue of approximately $3.2 million for Q4 2025, reflecting a 5% increase from Q3 2025, although it represents an 8% decline compared to Q4 2024, indicating challenges in revenue stability.
  • Strategic Partnership: The transformative out-license agreement with Future Pak for Mytesi provides $18 million upfront, with $16 million already received, which will support the development of its rare disease pipeline, enhancing Crofelemer's profitability.
  • Clinical Advancements: The company is in late-stage clinical development for rare disease intestinal failure, with promising data showing a reduction in parenteral support needs by up to 37%, and aims to file a new drug application by 2027, targeting a market opportunity estimated at $8 billion.
  • Market Challenges: Despite the partnership with Future Pak enhancing commercialization capabilities, prescription volume for Mytesi decreased by approximately 12.2% in Q4 2025 compared to the previous year, and the company faces regulatory approval challenges for new drug applications, which may impact future revenue growth.
Newsfilter
9.0
04-08Newsfilter
Jaguar Health Completes Study on Chemotherapy-Induced Diarrhea in Dogs
  • Study Completion: Jaguar Health announced the completion of its effectiveness study on crofelemer delayed-release tablets for chemotherapy-induced diarrhea in dogs, with results expected to be submitted in Q2 2026, potentially paving the way for full drug approval.
  • FDA Approval Renewal: The FDA has granted a fifth and final renewal of conditional approval for Canalevia-CA1 until December 21, 2026, underscoring the drug's significance in treating chemotherapy-induced diarrhea and addressing the market's need for effective solutions.
  • Significant Clinical Results: The use of crofelemer in dogs receiving neratinib chemotherapy resulted in a 30% reduction in both the incidence and severity of diarrhea, providing strong support for the drug's clinical application and effectiveness.
  • Large Market Potential: With approximately 90 million dogs in the U.S., over 11 million of which suffer from diarrhea annually, there is a pressing demand for effective treatment options, positioning Jaguar Health's product to fill this market gap.
seekingalpha
9.5
04-08seekingalpha
Jaguar Health Reports Q4 2025 Financial Results
  • Revenue Decline: Jaguar Health reported Q4 2025 revenue of $3.2 million, an 8.6% year-over-year decrease, indicating significant market pressure and sales challenges that could impact future liquidity and investor confidence.
  • Widening Net Loss: The net loss attributable to common shareholders increased to $53.6 million in 2025 from $38.5 million in 2024, reflecting a $15.1 million rise that highlights severe challenges in cost control and profitability, potentially raising shareholder concerns about the company's future.
  • Prescription Volume Drop: Mytesi prescription volume decreased by approximately 3.7% in 2025 compared to 2024, with a 5.8% decline in Q4 2025 over Q3 2025, suggesting weak market demand that may affect future revenue growth and market share.
  • Minimal License Revenue: The company recognized only $42,500 in license fees from a securities purchase agreement with a European partner in Q4 2025, indicating that revenues from non-prescription Neonorm products were negligible, which may limit the company's investment capacity in new product development.
Newsfilter
9.0
03-18Newsfilter
Jaguar Announces Extension of MVID Clinical Trial
  • Clinical Trial Extension: Napo Pharmaceuticals announced the initiation of a single-blind extension phase for its MVID trial, supported by the FDA, aiming to improve clinical outcomes by reducing parenteral support (PS) requirements, which could significantly lower co-morbidity risks associated with MVID.
  • Patient Participation: Currently, approximately 30% of MVID patients have completed the double-blind treatment phase, with clinical investigators supporting their participation in the single-blind extension phase to further assess the clinical benefits of crofelemer, enhancing treatment efficacy.
  • Regulatory Pathway Exploration: Jaguar anticipates that this extension phase may facilitate obtaining Breakthrough Therapy designation from the FDA, potentially providing expedited regulatory pathways for new drug approval to address the urgent treatment needs of this ultrarare disease.
  • Global Clinical Network: The clinical trial has sites in the US, Italy, and the UAE, having received approvals from the FDA, EMA, and respective health ministries, demonstrating Jaguar's commitment and capability to advance MVID treatment on a global scale.

Valuation Metrics

The current forward P/E ratio for Jaguar Health Inc (JAGX.O) is 200.00, compared to its 5-year average forward P/E of 1.16. For a more detailed relative valuation and DCF analysis to assess Jaguar Health Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
1.16
Current PE
200.00
Overvalued PE
24.57
Undervalued PE
-22.25

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.48
Current EV/EBITDA
-0.51
Overvalued EV/EBITDA
1.92
Undervalued EV/EBITDA
-2.88

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
1.98
Current PS
0.22
Overvalued PS
4.82
Undervalued PS
-0.87

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Frequently Asked Questions

What is Jaguar Health Inc (JAGX) stock price today?

The current price of JAGX is 6.96 USD — it has decreased -11.62

What is Jaguar Health Inc (JAGX)'s business?

Jaguar Health, Inc. is a commercial stage pharmaceuticals company. The Company is developing prescription medicines sustainably derived from plants from rainforest areas for people and animals with gastrointestinal distress, specifically associated with overactive bowel, which includes symptoms such as chronic debilitating diarrhea, urgency, bowel incontinence, and cramping pain. Its marketed drug Mytesi, (crofelemer 125 mg delayed-release tablets), is a first-in-class oral botanical drug product approved by the FDA for the symptomatic relief of noninfectious diarrhea in adults with HIV/AIDS on antiretroviral therapy. Its Canalevia-CA1, crofelemer delayed-release tablets drug, is an oral plant-based prescription product that is FDA conditionally approved to treat chemotherapy-induced diarrhea in dogs. It has an exclusive distribution agreement for the sale of Gelclair. It is developing a pipeline of prescription drug product candidates to address unmet needs in gastrointestinal health.

What is the price predicton of JAGX Stock?

Wall Street analysts forecast JAGX stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for JAGX is USD with a low forecast of USD and a high forecast of USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Jaguar Health Inc (JAGX)'s revenue for the last quarter?

Jaguar Health Inc revenue for the last quarter amounts to 3.23M USD, decreased -7.81

What is Jaguar Health Inc (JAGX)'s earnings per share (EPS) for the last quarter?

Jaguar Health Inc. EPS for the last quarter amounts to -4.38 USD, decreased -78.97

How many employees does Jaguar Health Inc (JAGX). have?

Jaguar Health Inc (JAGX) has 47 emplpoyees as of May 01 2026.

What is Jaguar Health Inc (JAGX) market cap?

Today JAGX has the market capitalization of 2.93M USD.