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DSGN Overview

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ET
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0.000
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ET
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Intellectia

Loading chart...

High
15.620
Open
15.620
VWAP
14.85
Vol
297.00K
Mkt Cap
908.12M
Low
14.400
Amount
4.41M
EV/EBITDA(TTM)
--
Total Shares
62.46M
EV
685.30M
EV/OCF(TTM)
--
P/S(TTM)
--
Design Therapeutics, Inc. is a biotechnology company. It is engaged in the research and development of GeneTACT molecules, which are small-molecule gene targeted chimera therapeutic candidates designed to be disease-modifying by addressing the underlying cause of diseases caused by inherited nucleotide repeat expansion mutations. Its Friedreich ataxia (FA) program is focused on the development of a disease-modifying treatment. Its DT-216 is developed to overcome the FXN transcription impairment that causes FA. DT-216 is in Phase I clinical trial. It is also engaged in developing DT-216 to enable higher exposure and chronic administration for treatment of FA, known as DT-216P2, which uses the same drug substance, DT-216. Its FECD program is focused on the development of a potentially disease-modifying medical treatment for FECD, DT-168, which is in Phase I clinical trial. Its Huntington's Disease program is focused on the development of a potentially disease-modifying treatment for HD.
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Events Timeline

(ET)
2026-05-12
16:20:00
Major Averages Finish Mixed as Semiconductor Stocks Pull Back
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2026-05-12
10:50:00
Trump Plans to Reduce Beef Import Tariffs
select
2026-05-11 (ET)
2026-05-11
12:30:00
Trump Approves Firing of FDA Commissioner Makary
select
link
2026-05-08 (ET)
2026-05-08
16:30:00
Dow Jones Slightly Up, Nasdaq Surges After Jobs Report
select
2026-05-08
13:40:00
Trump Signs Plan to Fire FDA Commissioner Makary
select
link
2026-04-28 (ET)
2026-04-28
16:10:00
Design Therapeutics Continues Advancing Clinical Programs
select

News

CNBC
6.5
00:03 AMCNBC
Investor Perspectives on Silicon Motion and BillionToOne
  • Silicon Motion Outlook: Investors express a positive outlook on Silicon Motion Technology (SIMO), with analysts recommending buying during pullbacks despite significant stock volatility, indicating confidence in its long-term growth potential.
  • Wynn's Challenges: Wynn Resorts faces significant investment issues in the Gulf region, and while its stock performance has been strong, management indicates a need to observe developments before making decisions, reflecting a cautious approach to market uncertainties.
  • Design Therapeutics Risks: Design Therapeutics is viewed as a high-risk investment, with investors needing to be aware of the potential for total loss, although the potential for doubling returns exists, highlighting the market's high uncertainty regarding its future performance.
  • BillionToOne Investment Advice: BillionToOne is favored by investors, with analysts suggesting a buy, indicating optimism about its business model and growth prospects, which may attract more investor attention.
Yahoo Finance
2.0
04-29Yahoo Finance
RESTORE-FA Trial Progressing Well with Promising Data Expected
  • Trial Progress: The RESTORE-FA trial is progressing well, with data expected in the second half of 2026, aiming to provide a go/no-go decision for the FA program and establish clinical proof of concept to inform future regulatory pathways.
  • Biomarker Evaluation: The study is evaluating endogenous frataxin levels in both blood and muscle, focusing on mRNA and protein to identify a potential primary surrogate biomarker that could reasonably predict clinical benefit.
  • Mechanism of DT216: DT216 is a heterobifunctional gene-targeted chimera designed to recognize long GA repeat expansions and increase normal frataxin RNA transcription, with cellular data suggesting that 10 nanomolar levels may be sufficient to increase frataxin with adequate exposure duration.
  • Dosing Structure: The dosing structure of the RESTORE-FA study began with escalations from 0.1 mg/kg to 0.6 mg/kg over four weeks, and a 1 mg/kg group has been initiated, incorporating 12-week treatment cohorts to generate additional exposure and data.
NASDAQ.COM
9.5
04-29NASDAQ.COM
Design Therapeutics Reports Q1 2026 Financial Results and Milestones
  • Improved Financial Performance: In Q1 2026, Design Therapeutics reported a net loss of $17.64 million, or $0.29 per share, down from $17.72 million and $0.31 per share in the previous year, indicating positive progress in cost control and operational efficiency.
  • Strong Cash Position: As of March 31, 2026, the company had $222.8 million in cash, cash equivalents, and investment securities, which is expected to fund operations into 2029, enhancing investor confidence in the company's long-term growth prospects.
  • Clinical Trial Progress: The ongoing RESTORE-FA trial for DT-216P2 in Friedreich's Ataxia patients is evaluating multiple ascending doses, with an update on its effect on endogenous frataxin levels anticipated in the second half of 2026, potentially offering new hope for treatment.
  • New Project Launch: In the Myotonic Dystrophy Type-1 (DM1) program, Design Therapeutics plans to initiate dosing of DM1 patients in the Phase 1 multiple-ascending dose trial for DT-818 in the first half of 2026, marking further expansion in the gene therapy space.
seekingalpha
9.5
03-09seekingalpha
Design Therapeutics Q4 Earnings Beat Expectations
  • Earnings Performance: Design Therapeutics reported a Q4 GAAP EPS of -$0.27, beating market expectations of -$0.37, indicating improvements in financial management and operational efficiency.
  • Strong Cash Reserves: As of December 31, 2025, the company held $219.8 million in cash, cash equivalents, and investment securities, which is expected to fund its operations through 2029, bolstering investor confidence in its long-term viability.
  • Increased Market Attention: The release of the earnings report has heightened interest in Design Therapeutics, with its Quant Rating on Seeking Alpha drawing significant attention, potentially attracting more investors and driving stock price appreciation.
  • Historical Financial Data Insights: The ongoing improvement in the company's historical financial data suggests that Design Therapeutics is gradually achieving its business objectives, positioning itself for a stronger market presence in the biopharmaceutical sector.
NASDAQ.COM
2.0
01-13NASDAQ.COM
FibroBiologics (FBLG) Stock Rises 7.68%, Attracts Market Attention
  • FibroBiologics Outperformance: FibroBiologics, Inc. (FBLG) surged 7.68% in after-hours trading to close at $0.41, indicating speculative interest or technical momentum despite no specific news.
  • Nyxoah Earnings Boost Confidence: Nyxoah SA (NYXH) advanced 3.94% to $5.28 after reporting preliminary Q4 and full-year 2025 results, with guidance for Q1 2026 enhancing investor confidence in its growth trajectory.
  • Fortress Biotech's Continued Volatility: Fortress Biotech, Inc. (FBIO) climbed 6.90% to $4.49 in after-hours trading, continuing a trend of volatility without any fresh news impacting the stock.
  • Revvity Collaboration Drives Growth: Revvity, Inc. (RVTY) posted a 4.92% gain to close at $109.00, as investors digest the January announcement of a collaboration with Eli Lilly to expand access to predictive models via the Revvity Signals platform.
NASDAQ.COM
8.0
2025-12-17NASDAQ.COM
Significant Options Trading on Wednesday: UTHR, URGN, DSGN
  • UroGen Pharma Options Activity: UroGen Pharma Ltd (URGN) has seen a significant options volume of 20,539 contracts today, equating to about 2.1 million underlying shares, which is 192% of its average daily trading volume over the past month.

  • High Volume Call Option for URGN: The $24 strike call option expiring on February 20, 2026, has particularly high activity with 10,010 contracts traded, representing approximately 1.0 million underlying shares.

  • Design Therapeutics Options Activity: Design Therapeutics Inc (DSGN) has recorded an options volume of 5,000 contracts today, representing around 500,000 underlying shares, which is 164.8% of its average daily trading volume over the past month.

  • High Volume Call Option for DSGN: The $9 strike call option expiring on January 16, 2026, has seen all 5,000 contracts traded today, corresponding to approximately 500,000 underlying shares.

Wall Street analysts forecast DSGN stock price to rise
4 Analyst Rating
Wall Street analysts forecast DSGN stock price to rise
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
13.00
Averages
15.00
High
18.00
Current: 0.000
sliders
Low
13.00
Averages
15.00
High
18.00
Cantor Fitzgerald
Overweight
initiated
AI Analysis
2026-05-12
New
Reason
Cantor Fitzgerald
Price Target
AI Analysis
2026-05-12
New
initiated
Overweight
Reason
Cantor Fitzgerald initiated coverage of Design Therapeutics with an Overweight rating. The firm expects DT-216P2, the company's lead asset which is designed to elicit improvements in endogenous frataxin production for Friedreich's ataxia, to continue to show clean safety and for some patients to see 20%-30%+ improvement in frataxin protein levels in the blood, the analyst tells investors in a research note. DT-216P2 is the clear near-term value driver of the Design Therapeutics story, the firm says.
Cantor Fitzgerald
Overweight
initiated
2026-05-12
New
Reason
Cantor Fitzgerald
Price Target
2026-05-12
New
initiated
Overweight
Reason
Cantor Fitzgerald initiated coverage of Design Therapeutics with an Overweight rating with no price target.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for DSGN
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Valuation Metrics

The current forward P/E ratio for Design Therapeutics Inc (DSGN.O) is 0.00, compared to its 5-year average forward P/E of -8.50. For a more detailed relative valuation and DCF analysis to assess Design Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-8.50
Current PE
0.00
Overvalued PE
-0.78
Undervalued PE
-16.23

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.38
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
2.08
Undervalued EV/EBITDA
-8.84

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

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DSGN logo
DSGN
Design Therapeutics Inc
596.41M

Whales Holding DSGN

B
Baker Bros. Advisors LP
Holding
DSGN
+6.07%
3M Return
F
Frazier Life Sciences Management, LP
Holding
DSGN
+4.47%
3M Return

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Frequently Asked Questions

What is Design Therapeutics Inc (DSGN) stock price today?

The current price of DSGN is 14.54 USD — it has decreased -6.91

What is Design Therapeutics Inc (DSGN)'s business?

Design Therapeutics, Inc. is a biotechnology company. It is engaged in the research and development of GeneTACT molecules, which are small-molecule gene targeted chimera therapeutic candidates designed to be disease-modifying by addressing the underlying cause of diseases caused by inherited nucleotide repeat expansion mutations. Its Friedreich ataxia (FA) program is focused on the development of a disease-modifying treatment. Its DT-216 is developed to overcome the FXN transcription impairment that causes FA. DT-216 is in Phase I clinical trial. It is also engaged in developing DT-216 to enable higher exposure and chronic administration for treatment of FA, known as DT-216P2, which uses the same drug substance, DT-216. Its FECD program is focused on the development of a potentially disease-modifying medical treatment for FECD, DT-168, which is in Phase I clinical trial. Its Huntington's Disease program is focused on the development of a potentially disease-modifying treatment for HD.

What is the price predicton of DSGN Stock?

Wall Street analysts forecast DSGN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for DSGN is15.00 USD with a low forecast of 13.00 USD and a high forecast of 18.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Design Therapeutics Inc (DSGN)'s revenue for the last quarter?

Design Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Design Therapeutics Inc (DSGN)'s earnings per share (EPS) for the last quarter?

Design Therapeutics Inc. EPS for the last quarter amounts to -0.29 USD, decreased -6.45

How many employees does Design Therapeutics Inc (DSGN). have?

Design Therapeutics Inc (DSGN) has 54 emplpoyees as of May 15 2026.

What is Design Therapeutics Inc (DSGN) market cap?

Today DSGN has the market capitalization of 908.12M USD.