TG Therapeutics (TGTX) Q1 2026 Earnings Transcript
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 2 days ago
0mins
Should l Buy TGTX?
Source: NASDAQ.COM
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Analyst Views on TGTX
Wall Street analysts forecast TGTX stock price to rise
4 Analyst Rating
3 Buy
0 Hold
1 Sell
Moderate Buy
Current: 43.025
Low
15.00
Averages
43.50
High
60.00
Current: 43.025
Low
15.00
Averages
43.50
High
60.00
About TGTX
TG Therapeutics, Inc. is a fully integrated, commercial stage biotechnology company focused on the acquisition, development and commercialization of novel treatments for B-cell diseases. Its products include Ublituximab IV (anti-CD20 mAb), Ublituximab IV Simplified Dosing Schedule, Ublituximab Subcutaneous (anti-CD20 mAb), and Azer-cel. It is engaged in late-stage clinical development of BRIUMVI. BRIUMVI is an anti-CD20 monoclonal antibody that can be administered to adults with relapsing forms of multiple sclerosis (RMS) in a one-hour infusion every 24 weeks, following the starting dose. It is used for treatment of adults with clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. The Company is also engaged in ULTIMATE I & II Trials Evaluating Single Agent Ublituximab in RMS. Its ENHANCE Phase 3b Trial is an ongoing, multi-center, open-label study designed to evaluate alternative dosing regimens for BRIUMVI in patients with RMS.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Revenue Beat: TG Therapeutics reported approximately $195 million in U.S. BRIUMVI net product revenue for Q1 2026, exceeding guidance of $185 million to $190 million, indicating strong market performance and sustained growth potential.
- Share Buyback Program: The company repurchased $100 million of its stock this quarter, which not only enhances shareholder value but also reflects management's confidence in future growth, likely increasing market recognition of its shares.
- Guidance Upgrade: Following a strong Q1, the company raised its 2026 U.S. revenue guidance to $885 million to $900 million, with global revenue guidance increased to approximately $925 million, signaling optimism about future performance.
- Clinical Trial Progress: Management expects to release top-line data from the ENHANCE study in the coming weeks and plans to launch subcutaneous BRIUMVI by 2028, pending regulatory approval, which could open new market opportunities for the company.
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- Market Rally: The S&P 500 and Nasdaq reached new highs fueled by optimistic expectations surrounding an Iran deal, indicating a significant rebound in investor confidence that could lead to increased capital inflows into the stock market.
- Tech Stocks Lead: Nvidia emerged as a market leader, driving a new wave of buying activity, reflecting strong investor confidence in its future growth potential, which may further enhance its market valuation.
- Arm Earnings Impact: Arm's earnings performance has become a focal point for the market, expected to positively influence related tech stocks and potentially trigger M&A activity within the industry, thereby invigorating market dynamics.
- Improved Investor Sentiment: As optimism about economic recovery grows, investors may reassess their allocations to risk assets, propelling the overall market upward and further solidifying the bullish trend in equities.
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- Revenue Outlook Raised: TG Therapeutics has raised its full-year 2026 revenue outlook to approximately $925 million from the previous range of $875 to $900 million, reflecting strong confidence in Briumvi sales and indicating significant future growth potential.
- Strong Q1 Performance: The company reported total revenue of $204.9 million for Q1, primarily driven by U.S. Briumvi sales of $194.8 million, exceeding Wall Street's estimate of $201.2 million, which highlights robust market demand for its lead product.
- Clinical Trial Progress: TG expects to report topline Phase 3 results from the Enhance trial of Briumvi around mid-2026, and plans to share early Phase 1 data for azer-cel in progressive multiple sclerosis in the second half of 2026, further enhancing its competitive position in the market.
- Investor Sentiment Shift: Following the release of positive financial guidance, TG Therapeutics' shares surged over 8% in just one day, with retail investor sentiment shifting from 'neutral' to 'extremely bullish', reflecting optimistic expectations for the company's future growth.
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- Earnings Highlights: TG Therapeutics reported a Q1 GAAP EPS of $0.12, missing expectations by $0.15, yet achieved revenues of $204.92 million, reflecting a 69.6% year-over-year increase and surpassing market expectations by $3.71 million, indicating robust market performance.
- Product Revenue Surge: The net product revenue for Q1 2026 reached $201.3 million, significantly up from $119.7 million in Q1 2025, primarily driven by BRIUMVI's sales in the U.S., which totaled $194.8 million, further solidifying its market position.
- Guidance Upgrade: The company raised its full-year 2026 global revenue target to approximately $925 million, exceeding the consensus of $900.34 million, while also increasing the U.S. net product revenue target for BRIUMVI to $885-$900 million, reflecting confidence in future performance.
- Cost Management: The projected operating expenses for 2026, defined as R&D and SG&A, are approximately $350 million, in addition to $100 million associated with BRIUMVI manufacturing costs, indicating effective cost control while pursuing expansion.
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